Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Study identifies cancer biomarkers based on a type of genetic modification

Biomarkers are often used during the management of cancer to guide treatment decisions and predict patient outcomes. However, it is often difficult to identify appropriate biomarkers that can be consistently reproduced and are easily analyzed with limited patient specimens.

18 May 2022

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

A research team at LKS Faculty of Medicine, The University of Hong Kong discovered that exosomes derived from γδ-T cells (γδ-T-Exos) synergised with radiotherapy can control nasopharyngeal carcinoma (NPC) by overcoming the radioresistance of NPC cancer stem cells (CSCs) and preserve their tumor-killing and T cell-promoting activities in the immunosuppressive NPC microenvironment.

18 May 2022

Immunotherapy after bladder cancer surgery helps reduce cancer recurrence

Immunotherapy after surgery helped reduce cancer recurrence in patients with urothelial cancer of the bladder or other sites in the urinary tract that had invaded the muscle and therefore posed a high risk for recurrence, according to clinical trial results presented at the American Urological Association annual meeting in May.

15 May 2022

Analysis reveals increasing prevalence of esophageal cancer and Barrett’s esophagus in middle-aged adults

Adults aged 45 to 64 experienced a nearly doubled rate of esophageal cancer and a 50 percent increase in the precancerous condition Barrett's esophagus between 2012 and 2019, according to a database analysis of roughly five million patients to be presented at Digestive Disease Week 2022.

13 May 2022

Penn study finds low uptake of first mutation-targeted bladder cancer drug

The first bladder cancer drug targeting a cancer-driving gene mutation has been used relatively little despite its clear efficacy in a clinical trial, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

12 May 2022

Perceived stigmatization is common among patients with NAFLD, study finds

About seven out of ten patients (69%) who suffer from non-alcoholic fatty liver disease (NAFLD) perceive some stigmatization in their daily life, according to a study led by a team of the University of Barcelona, the Liver and Digestive Diseases Networking Biomedical Research Centre, the Hospital Clínic de Barcelona and the August Pi i Sunyer Biomedical Research Institute.

12 May 2022

Research looks at potential of pantethine against SARS-CoV-2

In a recent study posted to the Research Square preprint server, researchers assessed the antiviral activity of pantethine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 May 2022

Deep learning reveals genetic determinants of COVID-19-associated mortality

In a recent study posted to the medRxiv* preprint server, researchers applied deep learning methods and identified genetic variants linked to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-caused mortality.

11 May 2022

Low-cost handheld device could cut the rate of unnecessary skin biopsies

Skin biopsies are no fun: doctors carve away small lumps of tissue for laboratory testing, leaving patients with painful wounds that can take weeks to heal.

5 May 2022

UrFU researchers propose the use of polyoxometallate nanoclusters as chemotherapy drug carrier

Researchers at Ural Federal University have proposed the use of polyoxometallate nanoclusters as a carrier for chemotherapy drug. It will help to deliver medications precisely to the focus of a pathological process, such as a cancerous tumor, without toxic effects on healthy cells.

28 Apr 2022

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

About one-fifth of often deadly head and neck cancers harbor genetic mutations in a pathway that is key to normal cell growth, and scientists report those mutations, which enable abnormal cancer cell growth, can also make the cancer vulnerable.

28 Apr 2022

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Researchers utilized a CRISPR/Cas9 system to evaluate the usage of tRNA by deleting two tRNA genes from the genomes of hyper hepatocellular carcinoma and human near-haploid chronic myeloid leukemia cells.

27 Apr 2022

Researchers reveal how not-yet-malignant cells “turn on” and become metastatic breast cancer

Mount Sinai researchers have discovered a previously unknown mechanism in which not-yet-malignant cells from early breast cancer tumors travel to other organs and, eventually, "turn on" and become metastatic breast cancer.

26 Apr 2022

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

New therapeutic option for HPV-positive head and neck carcinoma discovered

The various manifestations of head and neck carcinomas rank sixth in frequency worldwide and are fatal for about half a million people every year. In a quarter of cases, head and neck squamous cell carcinoma (HNSCC) is caused by human papillomavirus (HPV) and, currently, is not always treatable.

19 Apr 2022