Immune Response News and Research

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St. Jude Children's Research Hospital receives patent for genetically modified human immune cells for caner therapy

The United States Patent and Trademark Office today awarded St. Jude Children's Research Hospital U.S. patent number 8,399,645 for St. Jude's invention of compositions for genetically modifying human immune cells so they can destroy some of the most common forms of cancer in children and adults.

20 Mar 2013

Research findings could lead to development of new drugs for gout treatment

Findings from a Loyola University Chicago Stritch School of Medicine study could lead to the development of new drugs to treat gout.

20 Mar 2013

Protein derived from Pacific cod may inhibit prostate cancer, researchers say

Researchers at the University of Maryland School of Medicine have identified a peptide, or protein, derived from Pacific cod that may inhibit prostate cancer and possibly other cancers from spreading, according to preclinical research published online in the Proceedings of the National Academy of Sciences.

20 Mar 2013

Researchers find white blood cells produce and eliminate RBCs

Researchers at Albert Einstein College of Medicine of Yeshiva University and the Icahn School of Medicine at Mount Sinai have found that macrophages - white blood cells that play a key role in the immune response - also help to both produce and eliminate the body's red blood cells (RBCs).

18 Mar 2013

Cytomegalovirus employs a novel trick to hide from immune detection

A virus that most people have probably never heard of, yet most of us carry, is the number 1 infectious cause of congenital birth defects. One in 750 children are born with, or develop, permanent disabilities such as hearing loss or brain damage as a result of CMV (cytomegalovirus) infection in the womb.

17 Mar 2013

Study shows promising benefit of combination therapy in CRPC patients

Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer (CRPC) patients.

16 Mar 2013

Study: Flagellin plays a critical role in regulating host innate defences against UTIs

A new study by British scientists reveals that motile Escherichia coli isolates demonstrated significant activation of NF-κB signaling suggesting that flagellin plays a key role in up-regulating the host innate defences against urinary tract infections (UTIs).

15 Mar 2013

Research finding aids efforts toward cytomegalovirus vaccine

A virus most people probably have never heard of, but that the majority of us carry, is the No. 1 infectious cause of congenital birth defects in the U.S. today. Because of cytomegalovirus (CMV) infection during in utero development, 1 in 750 children are born with or develop permanent disabilities such as hearing loss or brain damage.

14 Mar 2013

UCSF study on T-cell behavior sheds light on how vaccines work

The immune system's T cells, while coordinating responses to diseases and vaccines, act like honey bees sharing information about the best honey sources, according to a new study by scientists at UC San Francisco.

14 Mar 2013

Pneumococcal vaccine pre-clinical development supported by £0.2 million award from Biomedical Catalyst

ImmBio (Immunobiology Ltd), a biopharmaceutical company developing innovative vaccines against serious infectious diseases, today announced that the UK government-backed Biomedical Catalyst has awarded the company approximately £0.2 million ($0.3 million) to support pre-clinical development of its pneumococcal vaccine, PnuBioVax™, which targets a wide range of strains of the bacteria.

12 Mar 2013

Influenza drug: an interview with Dr Jenny McKimm-Breschkin, CSIRO

Influenza or flu for short is caused by a family of viruses, which can be called influenza A or influenza B. Influenza A viruses are found in humans, animals – like swine and horses- and mostly aquatic birds. Influenza B is only found in humans.

11 Mar 2013

Cell fusion studies at Johns Hopkins could lead to improved treatments for muscular dystrophy

Researchers at Johns Hopkins have established a high-efficiency cell-cell fusion system, providing a new model to study how fusion works. The scientists showed that fusion between two cells is not equal and mutual as some assumed, but, rather, is initiated and driven by one of the fusion partners. The discovery, they say, could lead to improved treatments for muscular dystrophy, since muscle regeneration relies on cell fusion to make muscle fibers that contain hundreds or even thousands of nuclei.

8 Mar 2013

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Pfizer Inc. presented today the results from a Phase 3 study demonstrating the immunogenicity, tolerability and safety of Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine Diphtheria CRM197 Protein)in adults infected with human immunodeficiency virus (HIV).

5 Mar 2013

Study instructs how to design new, more powerful vaccine formulas for cancer

Cancer vaccines that attempt to stimulate an immune system assault fail because the killer T cells aimed at tumors instead find the vaccination site a more inviting target, scientists at The University of Texas MD Anderson Cancer Center report in Nature Medicine.

4 Mar 2013

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune response unable to kill off the tumour's cancerous cells.

2 Mar 2013

Combination of two environmental factors contributes to schizophrenia

The interplay between an infection during pregnancy and stress in puberty plays a key role in the development of schizophrenia, as behaviourists from ETH Zurich demonstrate in a mouse model. However, there is no need to panic.

2 Mar 2013

Griffith University's Institute for Glycomics launches human trials for Streptococcus A vaccine

Griffith University's Institute for Glycomics has launched human trials for a vaccine against Streptococcus A, the germ that causes rheumatic fever.

1 Mar 2013

Scientists identify two populations of human cells that migrate to the intestine

Researchers at Wake Forest Baptist Medical Center and colleagues have identified a special population of adult stem cells in bone marrow that have the natural ability to migrate to the intestine and produce intestinal cells, suggesting their potential to restore healthy tissue in patients with inflammatory bowel disease (IBD).

28 Feb 2013

Excess of vitamin D during pregnancy can increase risk of food allergy in children

Pregnant women should avoid taking vitamin D supplements. Substitution appears to raise the risk of children developing a food allergy after birth.

28 Feb 2013

Novel immunotherapy could potentially work like a vaccine against metastatic cancers

Preclinical, laboratory studies suggest a novel immunotherapy could potentially work like a vaccine against metastatic cancers, according to scientists at Virginia Commonwealth University Massey Cancer Center.

28 Feb 2013

Immune Response News and Research

St. Jude Children's Research Hospital receives patent for genetically modified human immune cells for caner therapy

Research findings could lead to development of new drugs for gout treatment

Protein derived from Pacific cod may inhibit prostate cancer, researchers say

Researchers find white blood cells produce and eliminate RBCs

Cytomegalovirus employs a novel trick to hide from immune detection

Study shows promising benefit of combination therapy in CRPC patients

Study: Flagellin plays a critical role in regulating host innate defences against UTIs

Research finding aids efforts toward cytomegalovirus vaccine

UCSF study on T-cell behavior sheds light on how vaccines work

Pneumococcal vaccine pre-clinical development supported by £0.2 million award from Biomedical Catalyst

Influenza drug: an interview with Dr Jenny McKimm-Breschkin, CSIRO

Cell fusion studies at Johns Hopkins could lead to improved treatments for muscular dystrophy

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Study instructs how to design new, more powerful vaccine formulas for cancer

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

Combination of two environmental factors contributes to schizophrenia

Griffith University's Institute for Glycomics launches human trials for Streptococcus A vaccine

Scientists identify two populations of human cells that migrate to the intestine

Excess of vitamin D during pregnancy can increase risk of food allergy in children

Novel immunotherapy could potentially work like a vaccine against metastatic cancers

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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