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New gene-silencing drugs cut cholesterol levels by half in early research

The first in a new class of gene-silencing drugs, known as inclisiran, has been shown to halve cholesterol levels in patients at risk of cardiovascular disease.

21 Mar 2017

TSRI researchers develop novel drug delivery method for treating cancers

Scientists from the Florida campus of The Scripps Research Institute have developed a new drug delivery method that produces strong results in treating cancers in animal models, including some hard-to-treat solid and liquid tumors.

16 Mar 2017

Study shows how mutations allow HCV to elude immune responses and vaccines

Unlike its viral cousins hepatitis A and B, hepatitis C virus (HCV) has eluded the development of a vaccine and infected more than 170 million people worldwide.

16 Mar 2017

Research findings advance development of HIV vaccines that induce broadly neutralizing antibodies

A Duke Health-led research team has described both the pathway of HIV protective antibody development and a synthetic HIV outer envelope mimic that has the potential to induce the antibodies with vaccination.

16 Mar 2017

Antibody treats pediatric brain tumors safely and effectively in mice

Five types of pediatric brain cancer were safely and effectively treated in mice by an antibody that causes immune cells to engulf and eat tumors without hurting healthy brain cells, according to a new study by researchers at the Stanford University School of Medicine.

15 Mar 2017

Study: Investigational Ebola vaccine regimen induced immune response that persisted for one year

A two-vaccine regimen intended to protect against Ebola virus disease induced an immune response that persisted for approximately one year in healthy adult volunteers, according to results from a Phase 1 clinical trial published in the March 14th issue of the Journal of the American Medical Association.

15 Mar 2017

New study examines immune responses to Ebola vaccines at one year after immunization

Immune responses to Ebola vaccines at one year after vaccination are examined in a new study appearing in the March 14 issue of JAMA.

14 Mar 2017

New technique opens door for biochemists to create better therapeutic antibodies

Antibodies are the foot soldiers of our immune system. These specialized, Y-shaped proteins attach to bacteria and viruses, where they either block the pathogen's activity directly, or signal the immune system's cells to destroy the invader.

14 Mar 2017

Study finds vaccines to be successful in preventing pandemic flu

Vaccines are successful in preventing pandemic flu and reducing the number of patients hospitalised as a result of the illness, a study led by academics at The University of Nottingham has found.

13 Mar 2017

Pre-existing immunity to dengue virus modulates T cell response to Zika infection

Although Zika and dengue are considered different virus "species," they are so closely related that the immune system treats Zika just like another version of dengue, report researchers at La Jolla Institute for Allergy and Immunology.

13 Mar 2017

Evolution of immuno-oncology

Immuno-oncology did not exist four years ago, it's a term coined by Dr. Axel Hoos, Head of the newly defined immuno-oncology department at GSK. He is also Senior Vice President Therapeutic Area (TA) and Head for Oncology R&D. Previously, it was referred to as cancer immunotherapy, but now it is called immuno-oncology (IO).

13 Mar 2017

Investigational RSV vaccine protects cattle from respiratory diseases

A novel vaccine developed by scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, protected cattle from respiratory syncytial virus (RSV) infection, according to research published online in npj Vaccines on March 8.

10 Mar 2017

New biomarkers may help in diagnosis and management of Crohn's disease

The diagnosis, understanding and management of Crohn's disease may have just received a helping hand from a joint ASU Biodesign Institute and Mayo Clinic study aimed at developing a better blood test for the disease.

9 Mar 2017

Mice study shows role of yeast in aggravating IBD symptoms

During the past decade, the gut has experienced a renaissance as investigations focus on the role of the microbiome on human health.

8 Mar 2017

Mayo Clinic researchers find new experimental drug that shrinks tumors in multiple myeloma patients

Mayo Clinic researchers have found that an experimental drug, LCL161, stimulates the immune system, leading to tumor shrinkage in patients affected by multiple myeloma. The findings are published in Nature Medicine.

8 Mar 2017

UCI chemists develop cheap, effective way to neutralize deadly snake venom

Chemists at the University of California, Irvine have developed a way to neutralize deadly snake venom more cheaply and effectively than with traditional anti-venom -- an innovation that could spare millions of people the loss of life or limbs each year.

7 Mar 2017

New drug-like compound shows potential to treat symptoms of lupus

Lupus, a chronic autoimmune disease, has proved difficult to treat, but a new international study co-led by a Rush University Medical Center researcher suggests that a drug starting through the pipeline could ameliorate or even eliminate the symptoms in most sufferers.

7 Mar 2017

Scientists use cargo-carrying red blood cells to alleviate autoimmune diseases in mouse models

Using red blood cells modified to carry disease-specific antigens, scientists in the laboratories of Hidde Ploegh and Harvey Lodish have prevented and alleviated two autoimmune diseases—multiple sclerosis (MS) and type 1 diabetes—in early stage mouse models.

7 Mar 2017

Researchers uncover new genetic clues linked to autoimmune kidney disease

Researchers have uncovered new genetic clues to understanding IgA nephropathy (IgAN), or Berger's disease, an autoimmune kidney disease and a common cause of kidney failure.

6 Mar 2017

EuroPrevent 2017 to explore innovative ideas in preventive cardiology

Innovations to prevent heart disease will take centre stage at EuroPrevent 2017 in Malaga, Spain. EuroPrevent is the annual congress of the European Association of Preventive Cardiology, a registered branch of the European Society of Cardiology.

6 Mar 2017