Genes News and Research

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Reverse phenotyping shows reactive T cell profiles in SARS-CoV-2 infection

A new study appearing as a preprint on the medRxiv* browser in December 2020 employs reverse phenotyping technology to explore T cell responses in COVID-19.

10 Dec 2020

Single N primer sufficient for SARS-CoV-2 molecular diagnosis

There is a huge and growing demand for better molecular diagnostic tests for COVID-19, as the pandemic shows few signs of coming under control.

10 Dec 2020

Skin may help to predict future heart problems

Our skin tells us when we've spent too much time in the sun or when the dry air of winter has sucked away too much moisture. Now Jefferson researchers find that the skin can also foretell issues unrelated to the protective barrier.

10 Dec 2020

UVA researchers identify genes that influence risk for common form of heart disease

Researchers at the University of Virginia have shed light on how our genes affect our risk for coronary artery disease, the most common form of heart disease.

10 Dec 2020

Study: TMEM41B transmembrane protein is a critical factor for SARS-CoV-2 replication

A single protein that appears necessary for the COVID-19 virus to reproduce and spread to other cells is a potential weakness that could be targeted by future therapies.

10 Dec 2020

Cancer Research UK announces dramatic cuts to its life-saving research budget

Cancer Research UK have announced today further dramatic cuts, slashing £45 million from its research budget.

10 Dec 2020

Toxin produced by E. coli bacteria also has nondiarrheal effects on the digestive tract

For people in wealthy countries, diarrhea is usually nothing more than an uncomfortable inconvenience for a few days. But for a poor child in a developing country, repeated bouts of diarrhea can lead to serious health consequences such as malnutrition, stunted growth and cognitive deficits.

9 Dec 2020

Researchers identify new therapeutic target to treat patients with type 1 diabetes

Researchers at the University of Utah School of Medicine have identified a new therapeutic target to treat patients with type 1 diabetes.

9 Dec 2020

Scientists shed light on how neurons form long-term memories

On a late summer day in 1953, a young man who would soon be known as patient H.M. underwent experimental surgery. In an attempt to treat his debilitating seizures, a surgeon removed portions of his brain, including part of a structure called the hippocampus. The seizures stopped.

9 Dec 2020

Study shows association between chemotherapy benefit and menopausal status in breast cancer patients

After a median follow-up of 5.1 years, among women with lymph node-positive early-stage breast cancer and a recurrence score of 25 or lower who received adjuvant endocrine therapy with or without chemotherapy, postmenopausal patients had no added benefit from chemotherapy, while premenopausal patients who received chemotherapy had improved invasive disease-free survival (IDFS) and an early indication of improved overall survival (OS), according to data from the SWOG S1007 RxPONDER clinical trial presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Evolutionary gene mutation unique to humans may be to blame for risk of advanced cancers

Compared to chimpanzees, our closest evolutionary cousins, humans are particularly prone to developing advanced carcinomas -- the type of tumors that include prostate, breast, lung and colorectal cancers -- even in the absence of known risk factors, such as genetic predisposition or tobacco use.

9 Dec 2020

Repair protein may prevent damage to healthy cells during cancer therapy

A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

9 Dec 2020

Scientists determine key molecular processes used by coronavirus to infect human cells

When a coronavirus--including SARS-CoV-2, which causes COVID-19--infects someone, it hijacks the person's cells, co-opting their molecular machinery for its own survival and spread.

9 Dec 2020

Study shows how YTHDF3 plays a significant role in cancer metastasis

Approximately 200,000 cancer patients are diagnosed with brain metastases each year, yet few treatment options exist because the mechanisms that allow cancer to spread to the brain remain unclear.

9 Dec 2020

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

A new study published on the preprint server bioRxiv in December 2020 reveals the role played by certain genetic factors in this group, in particular the FASLG gene belonging to the tumor necrosis factor (TNF) family.

8 Dec 2020

New 'nanoPCR' technology can accurately diagnose COVID-19 in less than 20 minutes

A "nanoPCR" technology was developed for the point-of-care (POC) diagnosis of coronavirus disease-19 (COVID-19).

8 Dec 2020

Researchers identify new gene variants that modify the risk of late-onset Alzheimer's disease

Late-onset Alzheimer's disease (LOAD) is the most common form of dementia in the elderly, affecting almost 44 million people worldwide.

8 Dec 2020

Study findings can guide personalized breast cancer therapies based on melatonin

A Brazilian study published in the Journal of Pineal Research describes a group of genes potentially regulated by the hormone melatonin in some types of cancer, especially breast cancer.

8 Dec 2020

Mice study shows how COVID-19 damages organs other than the lungs

UCLA researchers are the first to create a version of COVID-19 in mice that shows how the disease damages organs other than the lungs.

8 Dec 2020

Researchers identify new mechanism through which plants can regulate gene expression

Just like other organisms, plants must respond dynamically to a variety of cues over their lifetime. Going through different developmental stages, or altering their form in response to a drought or drastic temperature change requires altering which of their genes are expressed into proteins and when those processes occur.

8 Dec 2020

Genes News and Research

Reverse phenotyping shows reactive T cell profiles in SARS-CoV-2 infection

Single N primer sufficient for SARS-CoV-2 molecular diagnosis

Skin may help to predict future heart problems

UVA researchers identify genes that influence risk for common form of heart disease

Study: TMEM41B transmembrane protein is a critical factor for SARS-CoV-2 replication

Cancer Research UK announces dramatic cuts to its life-saving research budget

Toxin produced by E. coli bacteria also has nondiarrheal effects on the digestive tract

Researchers identify new therapeutic target to treat patients with type 1 diabetes

Scientists shed light on how neurons form long-term memories

Study shows association between chemotherapy benefit and menopausal status in breast cancer patients

Evolutionary gene mutation unique to humans may be to blame for risk of advanced cancers

Repair protein may prevent damage to healthy cells during cancer therapy

Scientists determine key molecular processes used by coronavirus to infect human cells

Study shows how YTHDF3 plays a significant role in cancer metastasis

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

New 'nanoPCR' technology can accurately diagnose COVID-19 in less than 20 minutes

Researchers identify new gene variants that modify the risk of late-onset Alzheimer's disease

Study findings can guide personalized breast cancer therapies based on melatonin

Mice study shows how COVID-19 damages organs other than the lungs

Researchers identify new mechanism through which plants can regulate gene expression

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