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CDC warns acute flaccid myelitis is poised for a comeback in kids this fall

As if the novel coronavirus pandemic was not enough! Now the United States Centre for Disease Control and Prevention (CDC) warns parents and pediatricians to be on the watch for a rare condition called Acute Flaccid Myelitis or AFM for short, which could affect young children and cause unexplained muscle paralysis similar to poliomyelitis. Their report is published today in the Morbidity and Mortality Weekly Report.

5 Aug 2020

Study reveals changes in transmissibility of SARS-CoV-2 due to D614G spike mutation

A recent research endeavor from the UK, currently available on the medRxiv preprint server, indicates that spike 614G variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) increases in frequency relative to 614D variant in a selective advantage manner – but without higher coronavirus disease (COVID-19) mortality rates.

5 Aug 2020

Treatment of unruptured intracranial aneurysms substantially reduces mortality rates

Mortality rates after treatment of unruptured intracranial aneurysms have substantially decreased in the past decade, according to new findings presented today at the Society of NeuroInterventional Surgery's (SNIS) 17th Annual Meeting.

5 Aug 2020

SNIS 17th Annual Meeting highlights COVID-19 and racial disparities in stroke treatment

The next frontier in neurointerventional surgery, including advances in stroke triage and management, innovations in artificial intelligence and robotics in endovascular surgery, new findings on racial disparities in stroke treatment and the neurologic impact of COVID-19 are a few of the topics that will be covered at the Society of NeuroInterventional Surgery's (SNIS) 17th Annual Meeting taking place virtually August 4-7, 2020.

5 Aug 2020

Interleukin-6 inhibitors appear to be a more effective treatment for COVID-19

New research from Boston Medical Center found that patients experiencing severe COVID-19 symptoms had improved outcomes when administered an Interleukin-6 (IL6ri) inhibitor, sarilumab or tocilizumab, given to mediate severe systemic inflammatory responses.

5 Aug 2020

Can Vitamin D help combat the coronavirus?

In a new report published in The Lancet, a team of researchers discussed the possibility that vitamin D could offer protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The meta-analyses of randomized controlled trials performed from 2007 to 2020.

4 Aug 2020

ACTG initiates novel clinical trial to evaluate multiple therapeutics for COVID-19

The AIDS Clinical Trials Group, the world's largest and longest established HIV research network, today announced the initiation of the ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies Trial, which will be conducted by the ACTG.

4 Aug 2020

Consumption of inorganic arsenic bearing rice associated with elevated cardiovascular mortality

Rice is the most widely consumed staple food source for a large part of the world's population. It has now been confirmed that rice can contribute to prolonged low-level arsenic exposure leading to thousands of avoidable premature deaths per year.

4 Aug 2020

Despite COVID-19 pressures, hospitals are maintaining emergency cardiac services in majority of cases

The death rate for patients who experienced what is normally a lower-risk heart attack rose sharply during the peak of the COVID-19 pandemic in England, according to an analysis of NHS data.

4 Aug 2020

Targeting LDL cholesterol to reduce heart disease risk now questioned

For many years, health experts have warned that high levels of bad cholesterol or low-density lipoprotein (LDL) are critical drivers for the development of cardiovascular disease. Now, a new study claims that decades of research have failed to show benefit of targeting the bad cholesterol to reduce the risk of cardiovascular disease.

4 Aug 2020

Darolutamide shows indication of considerable added benefit in prostate cancer

Up to now, adult men with non-metastatic castration-resistant prostate cancer (nmCRPC) at high risk of developing metastatic disease usually continued their conventional androgen deprivation therapy (ADT) while the cancer was observed for the occurrence of metastases (so-called watchful waiting).

3 Aug 2020

Research explains recognized sex differences in COVID-19 outcomes

The COVID-19 pandemic has notably taken a more significant toll on men compared to women, in terms of both disease severity and death. Now, a new study by researchers at the Icahn School of Medicine at Mount Sinai and published on the preprint server medRxiv in August 2020 confirms the increased risk that males have for death following COVID-19 while also highlighting worse outcomes in women with coronary artery disease, obesity, and hypoxia compared to men.

3 Aug 2020

Study shows high SARS-CoV-2 seroprevalence, but low death rate in Malawi's health care workers

A study by researchers from Malawi and United Kingdom reveals a significant discrepancy between predicted coronavirus disease (COVID-19) mortality in the observed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence rates in health care workers and reported deaths in urban Malawi in southeastern Africa, indicating early exposure, but a slow progression of the outbreak. Their findings are currently available on the medRxiv preprint server.

3 Aug 2020

Immune system's oldest branches may underpin COVID severity

One of the immune system's oldest branches, called complement, may be influencing the severity of COVID disease, according to a new study from researchers at Columbia University Irving Medical Center.

3 Aug 2020

American baby boomers have lower cognition scores than earlier generations

In a reversal of trends, American baby boomers scored lower on a test of cognitive functioning than did members of previous generations, according to a new nationwide study.

3 Aug 2020

Smartphone alert can aid laypersons in opioid overdose reversal

Without timely reversal, opioid overdose causes respiratory depression that may deteriorate into apnea, leading to brain injury and even death.

3 Aug 2020

Dexamethasone should be a standard drug in severe COVID-19

Many scientists have explored the use of new as well as already approved drugs for this condition, and one of the very few promising leads is dexamethasone. Dexamethasone is a corticosteroid, which has been reported in some earlier studies to reduce mortality in these patients by 18% and 36% in COVID-19 patients who are on oxygen and ventilators, respectively.

3 Aug 2020

Researchers identify differences in clinical features of non-obese patients with NAFLD

Researchers from the University of Tsukuba identify differences in the clinical features of non-obese patients with non-alcoholic fatter liver disease based on their sex and body mass index.

2 Aug 2020

There could be 7 million unplanned pregnancies because of COVID-19

The coronavirus pandemic has rippled across the globe, infecting nearly 18 million individuals worldwide to date. Though the coronavirus disease (COVID-19) affects people from all walks of life, women and girls may experience devastating effects of the outbreak.

2 Aug 2020

Meta-analysis shows 57% mortality reduction with convalescent plasma in COVID-19

Now, a new study published on the preprint server medRxiv in July 2020 reports that an older treatment modality, namely, the use of convalescent antibody-rich plasma, brings down the mortality rate in hospitalized COVID-19 patients by an astonishing 57%. This adds evidence for the use of convalescent plasma in the treatment of high-risk patients.

1 Aug 2020

Mortality News and Research

CDC warns acute flaccid myelitis is poised for a comeback in kids this fall

Study reveals changes in transmissibility of SARS-CoV-2 due to D614G spike mutation

Treatment of unruptured intracranial aneurysms substantially reduces mortality rates

SNIS 17th Annual Meeting highlights COVID-19 and racial disparities in stroke treatment

Interleukin-6 inhibitors appear to be a more effective treatment for COVID-19

Can Vitamin D help combat the coronavirus?

ACTG initiates novel clinical trial to evaluate multiple therapeutics for COVID-19

Consumption of inorganic arsenic bearing rice associated with elevated cardiovascular mortality

Despite COVID-19 pressures, hospitals are maintaining emergency cardiac services in majority of cases

Targeting LDL cholesterol to reduce heart disease risk now questioned

Darolutamide shows indication of considerable added benefit in prostate cancer

Research explains recognized sex differences in COVID-19 outcomes

Study shows high SARS-CoV-2 seroprevalence, but low death rate in Malawi's health care workers

Immune system's oldest branches may underpin COVID severity

American baby boomers have lower cognition scores than earlier generations

Smartphone alert can aid laypersons in opioid overdose reversal

Dexamethasone should be a standard drug in severe COVID-19

Researchers identify differences in clinical features of non-obese patients with NAFLD

There could be 7 million unplanned pregnancies because of COVID-19

Meta-analysis shows 57% mortality reduction with convalescent plasma in COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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