Amputation News and Research

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New treatment for severe frostbite

Using imaging to visualize areas lacking blood flow and deliver drugs via catheter, interventional radiologists are reopening recently frozen, clotted arteries with clot-busting and anti-spasmodic drugs.

18 Mar 2008

Genetic mutation linked to peripheral artery disease

The finding, appearing online in the journal Circulation, is the first to document a genetic mutation linked to PAD. Although the work was done in mice, researchers say it is likely to give them new insight into how PAD develops and progresses in humans.

26 Feb 2008

Researcher transplants stem cells to try to save patients' legs

A Northwestern University Feinberg School of Medicine researcher has launched the first U.S. trial in which a purified form of subjects' own adult stem cells was transplanted into their leg muscles with severely blocked arteries to try to grow new small blood vessels and restore circulation in their legs.

23 Jan 2008

Racial and ethnic differences among patients with extremity soft-tissue sarcomas

A new study reveals significant racial and ethnic differences in the treatment and survival of patients with soft-tissue sarcomas, a rare but dangerous cancer that begins in muscle, fat, blood vessels or other supporting tissue of the body.

23 Jan 2008

New meningitis vaccine a potential new weapon against the deadly disease

In a joint venture British and Canadian researchers have found that a new type of meningitis vaccine offers immunity to infants as young as six months from the deadly disease.

9 Jan 2008

Threat women face from vascular disease not widely understood

Though arterial vascular disease is widespread and often deadly among older American women, doctors too often fail to spot and treat it, according to a new report by a team of vascular surgeons from the Columbia University Medical Center and Weill Cornell Medical College campuses of NewYork-Presbyterian Hospital.

21 Nov 2007

GlaxoSmithKline implements changes to the US product label for Avandia

GlaxoSmithKline announced today that it is implementing changes to the US product label for Avandia(R) (rosiglitazone maleate), based on an extensive and thorough review by the FDA of myocardial ischemia data on Avandia, the most widely studied oral anti-diabetic medicine available.

15 Nov 2007

More than six out of ten people with diabetes are walking around in the wrong-sized shoes

More than six out of ten people with diabetes are walking around in the wrong-sized shoes, exposing themselves to serious foot problems that could lead to amputation, according to research in the November issue of IJCP, the International Journal of Clinical Practice.

14 Nov 2007

Targeted muscle reinnervation allows prosthetic arms to brain's signals

Motorized prosthetic arms can help amputees regain some function, but these devices take time to learn to use and are limited in the number of movements they provide.

13 Nov 2007

French clay fights flesh-eating bug

French clay that kills several kinds of disease-causing bacteria is at the forefront of new research into age-old, nearly forgotten, but surprisingly potent cures.

25 Oct 2007

Charcot foot becoming more common

Charcot foot is a sudden softening of the foot's bones caused by severe neuropathy, or nerve damage, a common diabetic foot complication. It can trigger an avalanche of problems, including joint loss, fractures, collapse of the arch, massive deformity, ulcers, amputation, and even death. As the disorder progresses, the bottom of the foot can become convex, bulging like the hull of a ship.

24 Oct 2007

FDA expands approved age range for Menactra, bacterial meningitis vaccine

The U.S. Food and Drug Administration has expanded the approved age range for Menactra, a bacterial meningitis vaccine, to include children ages 2 to 10 years.

19 Oct 2007

Honey for wound healing

Surgeons are being advised to consider the supermarket as well as the drugs cupboard when it comes to effective wound healing, according to a research review published in the October issue of IJCP, the International Journal of Clinical Practice.

18 Oct 2007

Neural prosthetic devices

MIT researchers have developed a new algorithm to help create prosthetic devices that convert brain signals into action in patients who have been paralyzed or had limbs amputated.

4 Oct 2007

Discovery of genetic roadblock could lead to novel treatments for type 2 diabetes

A team of Mount Sinai Hospital researchers has found that a “genetic roadblock” identified in a recent study could pave the way toward novel treatments for type 2 diabetes.

3 Oct 2007

Caribbean health authorities promise to reduce healthcare-associated infections

Health authorities from the Caribbean say they will work to reduce healthcare-associated infections through a series of actions that include getting healthcare providers to improve hand hygiene.

2 Oct 2007

Many patients with diabetes say burden of care rivals complications of disease

Many patients with diabetes say that the inconvenience and discomfort of constant therapeutic vigilance, particularly multiple daily insulin injections, has as much impact on their quality of life as the burden of intermediate complications, researchers from the University of Chicago report in the October 2007 issue of Diabetes Care.

27 Sep 2007

Clinical trials for diabetes drugs should measure outcomes important to patients

Most clinical trials for new diabetes drugs do not consider the impact medication will have on a patient's quality of life or other outcomes that are important to patients, such as the risk of developing complications associated with diabetes, according to a Mayo Clinic commentary in the current issue of The Lancet.

27 Sep 2007

African American and Latino diabetics far less likely to blood sugar under control

Despite decades of advances in diabetes care, African Americans and Latinos are still far less likely than whites to have their blood sugar under control, even with the help of medications, a new nationally representative study finds.

25 Sep 2007

New device for clearing blocked arteries in the legs receives FDA approval

Cardiovascular Systems, Inc. (CSI) has announced that the U.S. Food and Drug Administration (FDA) has cleared the use of the Diamondback 360 Orbital Atherectomy System (OAS) for removing plaque blockages in the legs (peripherals) and restoring blood flow.

25 Sep 2007