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Study uncovers mechanisms by which microRNAs drive atherogenesis in a cell-type-specific manner

Researchers at the University of Eastern Finland have uncovered potential mechanisms by which microRNAs (miRNA) drive atherogenesis in a cell-type-specific manner.

2 Jun 2021

Optic nerve activity may trigger the formation of vision-harming tumors in children

In a study of mice, researchers showed how the act of seeing light may trigger the formation of vision-harming tumors in young children who are born with neurofibromatosis type 1 (NF1) cancer predisposition syndrome.

2 Jun 2021

Scientists test antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus

Army scientists working as part of an international consortium have developed and tested an antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus (CCHFV), which is carried by ticks and kills up to 60 percent of those infected.

2 Jun 2021

New algorithm could be an important step toward adaptive deep brain stimulation

By delivering small electrical pulses directly to the brain, deep brain stimulation (DBS) can ease tremors associated with Parkinson's disease or help relieve chronic pain.

1 Jun 2021

Malaria parasites may survive, replicate within the spleen of asymptomatic individuals, study suggests

Malaria, a disease caused mainly by the parasites Plasmodium falciparum and Plasmodium vivax, (P. vivax) is associated with over 400,000 deaths each year.

1 Jun 2021

NIH starts Phase 1/2 clinical trial evaluating mixed COVID-19 vaccine schedules

The National Institutes of Health has started a Phase 1/2 clinical trial in which adult volunteers who have been fully vaccinated against COVID-19 will receive booster doses of different COVID-19 vaccines to determine the safety and immunogenicity of mixed boosted regimens.

1 Jun 2021

Unique observational tool developed for assessing children with concussion

A research team led by scientists at Université de Montréal has developed a unique observational tool for assessing children up to 5 years of age who have had a concussion.

1 Jun 2021

Study supports the need for improving early TB diagnosis and care in Irish prisons

Investigators from Trinity College Dublin, the Irish Mycobacteria Reference Laboratory, St James's Hospital, and the Department of Public Health HSE East believe tuberculosis (TB) care in Irish Prisons should be supported, considering the findings of their study which is published today (Tuesday, 1st June, 2021) in the International Journal of Tuberculosis and Lung Disease.

1 Jun 2021

Odor-based test could serve as a non-invasive approach to screen for harder-to-detect cancers

An odor-based test that sniffs out vapors emanating from blood samples was able to distinguish between benign and pancreatic and ovarian cancer cells with up to 95 percent accuracy, according to a new study from researchers at the University of Pennsylvania and Penn's Perelman School of Medicine.

1 Jun 2021

New discovery in Ewing sarcoma may prevent tumor metastasis from occurring

A new discovery in Ewing sarcoma, an aggressive and often fatal childhood cancer, has uncovered the potential to prevent cancer cells from spreading beyond their primary tumor site.

1 Jun 2021

UTokyo researchers study worms to understand the neuroplasticity of learning

As anyone who has ever procrastinated knows, remembering that you need to do something and acting on that knowledge are two different things. To understand how learning changes nerve cells and leads to different behaviors, researchers studied the much simpler nervous system of worms.

1 Jun 2021

New genetic resource may lead to prevention and treatment strategies for malaria

A new extensive genetic resource of rat-infecting malaria parasites may help advance the development of malaria prevention and treatment strategies.

1 Jun 2021

Can depression increase the likelihood of rapid kidney function decline?

In a recent study, the presence of depressive symptoms in normally healthy individuals was found to correlate with rapid kidney function decline.

1 Jun 2021

FDA approves investigational monoclonal antibody therapy sotrovimab for COVID-19

The U.S. Food and Drug Administration (FDA) has given the green light on the investigational monoclonal antibody therapy, sotrovimab, as a coronavirus disease (COVID-19) treatment.

1 Jun 2021

Using Sotrovimab to treat COVID-19 early

A new study published on the medRxiv* preprint server hypothesized that a monoclonal antibody that has the capability to neutralize all sarbecoviruses could also be used to target a highly conserved epitope. This conserved sequence has a high probability of remaining unchanged in SARS-CoV-2 variants.

31 May 2021

Function and regeneration of dendritic cells impaired in COVID-19

A group of researchers from Germany has investigated and analyzed circulating dendritic cells and monocyte subsets in 65 hospitalized COVID-19 patients with mild to severe presentations of the infection. A variety of patients were included in their study, from those who exhibited minor signs of acute disease to convalescents, as well as healthy controls

31 May 2021

Report on the effectiveness of mRNA-1273 and BNT162b2 COVID-19 vaccines in Canada

The report has recently been published on the preprint server medRxiv* by Kwong et al. (May 28th, 2021) and focused on the Pfizer-BioNTech or Moderna vaccines, confirming the supposed greater efficacy in preventing infection or severe outcomes following the administration of two doses.

31 May 2021

Cognitive reappraisal may reduce compulsive drug-seeking behavior in cocaine-addicted individuals

An emotion regulation strategy known as cognitive reappraisal helped reduce the typically heightened and habitual attention to drug-related cues and contexts in cocaine-addicted individuals, a study by Mount Sinai researchers has found.

31 May 2021

AI models look for shortcuts that could lead to errors in diagnosis of COVID-19

Artificial intelligence promises to be a powerful tool for improving the speed and accuracy of medical decision-making to improve patient outcomes.

31 May 2021

Expanding genomic research into different ancestries yields more and better results

Today The Lundquist Institute announced that its investigators contributed data from several studies, including data on Hispanics, African-Americans and East Asians, to the international MAGIC collaboration, composed of more than 400 global academics, who conducted a genome-wide association meta-analysis led by the University of Exeter.

31 May 2021

Laboratory News and Research

Study uncovers mechanisms by which microRNAs drive atherogenesis in a cell-type-specific manner

Optic nerve activity may trigger the formation of vision-harming tumors in children

Scientists test antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus

New algorithm could be an important step toward adaptive deep brain stimulation

Malaria parasites may survive, replicate within the spleen of asymptomatic individuals, study suggests

NIH starts Phase 1/2 clinical trial evaluating mixed COVID-19 vaccine schedules

Unique observational tool developed for assessing children with concussion

Study supports the need for improving early TB diagnosis and care in Irish prisons

Odor-based test could serve as a non-invasive approach to screen for harder-to-detect cancers

New discovery in Ewing sarcoma may prevent tumor metastasis from occurring

UTokyo researchers study worms to understand the neuroplasticity of learning

New genetic resource may lead to prevention and treatment strategies for malaria

Can depression increase the likelihood of rapid kidney function decline?

FDA approves investigational monoclonal antibody therapy sotrovimab for COVID-19

Using Sotrovimab to treat COVID-19 early

Function and regeneration of dendritic cells impaired in COVID-19

Report on the effectiveness of mRNA-1273 and BNT162b2 COVID-19 vaccines in Canada

Cognitive reappraisal may reduce compulsive drug-seeking behavior in cocaine-addicted individuals

AI models look for shortcuts that could lead to errors in diagnosis of COVID-19

Expanding genomic research into different ancestries yields more and better results

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Advancing degrader and proximity-based drug development

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo