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AUA updates clinical practice guideline on female stress urinary incontinence

A complete evaluation, including an assessment of post-void residual volume, is key when evaluating a female patient for surgery to treat stress urinary incontinence (SUI), according to a new clinical practice guideline released today by the American Urological Association (AUA).

8 Jan 2010

Chinese researchers become the world's fifth most prolific contributors to regenerative medicine

Chinese researchers have become the world's fifth most prolific contributors to peer-reviewed scientific literature on clock-reversing regenerative medicine even as a skeptical international research community condemns the practice of Chinese clinics administering unproven stem cell therapies to domestic and foreign patients.

8 Jan 2010

Majority of long-term cancer survivors do not have access to personalized care services

An increasing number of people are surviving cancer, but many do not receive the services and support they need in the long term, Macmillan Cancer Support has said.

8 Jan 2010

Findings shed new light on the molecular mechanisms of visual system in brain

The laboratory of Dr. Fr-d-ric Charron, a researcher at the Institut de recherches cliniques de Montr-al (IRCM), has discovered a new molecular mechanism that permits the guidance of visual nerves towards the brain.

8 Jan 2010

University Hospitals Case Medical Center conducts Phase 2 clinical trial of gene therapy for AD

University Hospitals Case Medical Center is one of 12 sites conducting the first Phase 2 clinical trial of a gene therapy for Alzheimer's disease (AD). The study uses a viral-based gene transfer system called CERE-110, which is designed to deliver nerve growth factor (NGF) into the brain.

8 Jan 2010

New genetic findings may lead to better interventional therapies for obsessive compulsive disorders

A collaboration between the University of Massachusetts Medical School, the Cummings School of Veterinary Medicine at Tufts University and the Broad Institute at the Massachusetts Institute of Technology has identified a genetic locus on canine chromosome 7 which coincides with an increased risk of obsessive compulsive disorder (OCD) susceptibility.

7 Jan 2010

Researchers seek to defeat Alzheimer's disease by modifying mice's immune system

Using laboratory mice that had been bred to have brain changes similar to Alzheimer's disease, scientists were able to reduce two characteristic features of the disease by modifying the mice's immune systems with a special peptide (MOG45D) related to the myelin sheath that insulates nerve cells and nerve fibers. As a result, anti-inflammatory cells were recruited from the blood into the brain, dampening the local inflammatory response.

7 Jan 2010

Researchers identify new approach to eliminate side effects of drugs

Researchers at the Stanford University School of Medicine have taken an early step toward identifying a new approach to drug discovery that may eventually yield drugs with fewer side effects.

7 Jan 2010

MSU researcher discovers link between diabetes and bone marrow nerve damage

A research team led by a Michigan State University professor has discovered a link between diabetes and bone marrow nerve damage that may help treat one of the disease's most common and potentially blindness-causing complications.

7 Jan 2010

Animal experiments show old antidepressant may reverse heart failure

A team of Johns Hopkins and other researchers have found in animal experiments that an antidepressant developed over 40 years ago can blunt and even reverse the muscle enlargement and weakened pumping function associated with heart failure.

6 Jan 2010

Perturbing DISC1 gene could help researchers treat mental illness, says study

Scientists have long eyed mutations in a gene known as DISC1 as a possible contributor to schizophrenia and mood disorders, including depression and bipolar disorder. Now, new research led by Johns Hopkins researchers suggests that perturbing this gene during prenatal periods, postnatal periods or both may have different effects in mice, leading to separate types of brain alterations and behaviors with resemblance to schizophrenia or mood disorders.

6 Jan 2010

WPI researchers lay groundwork for new generation of advanced prosthetic limbs

The conflicts in Iraq and Afghanistan have left a terrible legacy: more than 1,200 returning American soldiers have lost one or more limbs. To address this growing national need, researchers at Worcester Polytechnic Institute (WPI) are laying the groundwork for a new generation of advanced prosthetic limbs that will be fully integrated with the body and nervous system.

5 Jan 2010

Elevated diabetes risk associated with smoking cessation, but lifestyle changes can help combat risk

Cigarette smoking is a well-known risk factor for type 2 diabetes, but new research from Johns Hopkins suggests that quitting the habit may actually raise diabetes risk in the short term.

5 Jan 2010

Talampanel slows progression of amyotrophic lateral sclerosis

A drug already used to treat symptoms of epilepsy has potential to slow the muscle weakening that comes with amyotrophic lateral sclerosis (ALS), scientists report after completing a Phase II clinical trial-an early, small-scale test to show if the drug works and continues to be safe.

5 Jan 2010

Scientists identify genetic marker to diagnose DFTD

An international team of scientists led by a Cold Spring Harbor Laboratory (CSHL) investigator has discovered that the deadly facial tumors decimating Australia's Tasmanian devil population probably originated in Schwann cells, a type of tissue that cushions and protects nerve fibers.

4 Jan 2010

TENS therapy is not effective against chronic low-back pain

A new guideline issued by the American Academy of Neurology finds that transcutaneous electric nerve stimulation (TENS), a widely used pain therapy involving a portable device, is not recommended to treat chronic low-back pain that has persisted for three months or longer because research shows it is not effective.

31 Dec 2009

Tarantula venom protein promising for MD

University at Buffalo biophysicists have found a protein in tarantula venom that shows promise as a potential therapy for muscular dystrophy (MD). They have formed a start-up biotech company in Buffalo -- Rose Pharmaceuticals -- to advance the drug to clinical trials.

30 Dec 2009

OSU researchers study biological and mechanical principles of cockroach to build robots

The sight of a cockroach scurrying for cover may be nauseating, but the insect is also a biological and engineering marvel, and is providing researchers at Oregon State University with what they call "bioinspiration" in a quest to build the world's first legged robot that is capable of running effortlessly over rough terrain.

29 Dec 2009

Study explains how semaphorin gene regulates synapse formation

By combining a research technique that dates back 136 years with modern molecular genetics, a Johns Hopkins neuroscientist has been able to see how a mammal's brain shrewdly revisits and reuses the same molecular cues to control the complex design of its circuits.

29 Dec 2009

New evidence suggests amyloid beta plays a critical role in synaptic failure

The early stages of Alzheimer's disease are thought to occur at the synapse, since synapse loss is associated with memory dysfunction. Evidence suggests that amyloid beta (Aβ) plays an important role in early synaptic failure, but little has been understood about Aβ's effect on the plasticity of dendritic spines.

29 Dec 2009

Nerve News and Research

AUA updates clinical practice guideline on female stress urinary incontinence

Chinese researchers become the world's fifth most prolific contributors to regenerative medicine

Majority of long-term cancer survivors do not have access to personalized care services

Findings shed new light on the molecular mechanisms of visual system in brain

University Hospitals Case Medical Center conducts Phase 2 clinical trial of gene therapy for AD

New genetic findings may lead to better interventional therapies for obsessive compulsive disorders

Researchers seek to defeat Alzheimer's disease by modifying mice's immune system

Researchers identify new approach to eliminate side effects of drugs

MSU researcher discovers link between diabetes and bone marrow nerve damage

Animal experiments show old antidepressant may reverse heart failure

Perturbing DISC1 gene could help researchers treat mental illness, says study

WPI researchers lay groundwork for new generation of advanced prosthetic limbs

Elevated diabetes risk associated with smoking cessation, but lifestyle changes can help combat risk

Talampanel slows progression of amyotrophic lateral sclerosis

Scientists identify genetic marker to diagnose DFTD

TENS therapy is not effective against chronic low-back pain

Tarantula venom protein promising for MD

OSU researchers study biological and mechanical principles of cockroach to build robots

Study explains how semaphorin gene regulates synapse formation

New evidence suggests amyloid beta plays a critical role in synaptic failure

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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