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New approach may prove useful in labor anesthesia, orthopedics and more

One of the holy grails of local anesthesia is the ability to achieve a long-lasting nerve block that eliminates pain sensation while not affecting motor function. Now, researchers at Children's Hospital Boston have discovered an anesthetic approach that seems to do just that.

2 Feb 2010

Tips to ease prenatal back and neck pain from LSI

One of the most common discomforts experienced by women during pregnancy is back pain. Expectant mothers endure a variety of different types of backache as their hormones and posture change during pregnancy.

2 Feb 2010

Genetic mutations may trigger suicidal behavior in depressed patients

Single mutations in genes involved with nerve cell formation and growth appear to be associated with the risk of attempting suicide among individuals with depression, according to a report posted online today that will appear in the April print issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

2 Feb 2010

FDA approves neurostimulation treatment for heart failure

The FDA recently approved the first study of neurostimulation as a treatment for heart failure, a chronic disease that affects nearly six million Americans and is the leading cause of hospitalization in America.

2 Feb 2010

Evidence suggests antidepressants may improve post-stroke recovery

Patients who received the antidepressant escitalopram following a stroke appeared to recover more of their thinking, learning and memory skills than those taking placebo or participating in problem-solving therapy, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

2 Feb 2010

Cochlear implantation enables quality of life equal to normal hearing peers

Children who have cochlear implants (CI) rank their quality of life (QOL) equal to their normally hearing (NH) peers, indicates new research in the February 2010 issue of Otolaryngology - Head and Neck Surgery.

1 Feb 2010

Muscle-sparing treatments could improve patient outcomes and reduce costs

A University of Kentucky researcher is investigating respiratory weakness as a factor in the morbidity of intensive-care patients and will soon be testing new treatments that could improve long-term patient outcomes while reducing costs of care.

30 Jan 2010

Study may lead to preventative and therapeutic treatments for MS patients

Previous studies have shown multiple sclerosis (MS) patients are more often born in spring than in any other season, indicating that there is an environmental risk factor for the disease. A paper in the journal Neurology, reviewed for f1000 Medicine by Emmanuelle Waubant and Ellen Mowry, now suggests that this seasonal effect is mediated by the gene HLA-DRB1.

30 Jan 2010

Diamyd Medical announces share capital and total number of shares as of January 29, 2010

As of January 29, 2010, the share capital in Diamyd Medical AB (publ.) is 14 330 494 SEK. The total number of votes is 4 160 187 and the total number of shares is 28 660 988, divided among 1 437 876 shares of series A (1 vote) and 27 223 112 shares of series B (1/10 vote).

29 Jan 2010

Diabetes vaccine: Diamyd Medical to file for market approval in 2011

In her comments in today’s quarterly report Elisabeth Lindner, President and CEO of Diamyd Medical, says that the Company’s objective is to file the Diamyd® diabetes vaccine for market approval in 2011 - a goal that isn’t very far off now.

29 Jan 2010

Surgeons have a lower preference for back surgery than family doctors

Surgeons are less likely than family physicians or patients to view surgery as the preferred treatment option for low back pain, according to a study in the January 1 issue of Spine.

29 Jan 2010

Regis Technologies' 4-Aminopyridine manufacturing facility receives FDA's EIR and PAI approval

Regis Technologies, Inc., a leading provider of cGMP and non-GMP synthesis and separations services for active pharmaceutical ingredients (APIs) and intermediates, announced it has received an Establishment Inspection Report (EIR) from the U.S. Food and Drug Administration (FDA) stating that Regis passed the FDA’s pre-approval inspection (PAI) for its manufacture of 4-Aminopyridine the active ingredient in Ampyra™.

29 Jan 2010

New Jersey surgeons perform multi-process procedure for spinal cord injuries

The Plastic Surgery Center today announced that in a highly rare procedure for spinal cord injuries, a New Jersey medical team led by Dr. Matthew Kaufman enabled a 51-year-old man to breathe on his own - without a ventilator - for the first time since becoming paralyzed.

29 Jan 2010

Scientists discover mechanism that regulates prolactin hormone

A mechanism for regulating the hormone prolactin has newly been revealed by scientists at Karolinska Institutet. The results are to be published in the scientific journal Neuron, and may be significant for conditions and functions such as breast-feeding, sexual libido, and metabolism.

28 Jan 2010

Research suggests pomegranate seed extract could stimulate uterine contractions

The team identified beta-sitosterol - a steroid that can inhibit the absorption of cholesterol in the intestine - as the main constituent of pomegranate seed extract. The research suggests that pomegranate extract could be used as a natural stimulant to encourage the uterus to contract during labour.

28 Jan 2010

Researchers to test newest implant in restoring vision damaged by disease

Researchers trying to restore vision damaged by disease have found promise in a tiny implant that sows seeds of new cells in the eye.

28 Jan 2010

New insight into reprogramming of cells

A discovery by Babraham scientists brings new insight into how cells are reprogrammed and a greater understanding of how the environment, or factors like nutritional signals, can interact with our genes to affect health. As an embryo develops, cells acquire a particular fate, for example becoming a nerve or skin cell. The findings, reported online in the journal Nature, pinpoint a protein called AID as being important for complete cellular reprogramming in mammals.

28 Jan 2010

Blocking CRF may prevent excessive alcohol consumption

A team of scientists from The Scripps Research Institute has found that a specific stress hormone, the corticotropin-releasing factor (CRF), is key to the development and maintenance of alcohol dependence in animal models.

28 Jan 2010

Pfizer's new pipeline shows growth and diversity in research and development

Pfizer Inc. today provided an update to its pipeline for the first time since the close of the acquisition of Wyeth in October, 2009. The new development pipeline, composed of assets from both legacy companies, includes 133 programs from phase 1 through registration, and shows growth and increased diversity in each of the areas where the company invests in research and development.

28 Jan 2010

MedCI forms new strategic alliance with Genta

MedCI LLC, a life-science business consulting services company, announced the formation of a new strategic alliance with Genta Incorporated to secure licensing partners for Genta’s small molecule oncology compound, tesetaxel.

28 Jan 2010