Vascular News and Research

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New tissue engineering technique may help stem cells generate solid organs

Stem cells can thrive in segments of well-vascularized tissue temporarily removed from laboratory animals, say researchers at the Stanford University School of Medicine.

2 Mar 2009

Angiogenesis inhibitors, study points to limitations, solutions

A new generation of cancer drugs designed to starve tumors of their blood supply - called "angiogenesis inhibitors"-succeeds at first, but then promotes more invasive cancer growth-sometimes with a higher incidence of metastases, according to a new study in animals.

2 Mar 2009

New study finds increased prevalence of left-handedness in children with facial development disorder

A new study by physician researchers from Hasbro Children's Hospital and Children's Hospital Boston has identified an increased prevalence in left-handedness in children with a congenital disorder known as hemifacial microsomia (HFM).

2 Mar 2009

The obesity paradox

It's called the obesity paradox. Although obese people are more apt to suffer from inflammatory diseases, such as diabetes, heart disease, and stroke, they are also more likely to survive a major attack caused by one of those conditions.

26 Feb 2009

Spun-sugar filaments show potential for regenerating nerves

Researchers at Purdue University have developed a technique using spun-sugar filaments to create a scaffold of tiny synthetic tubes that might serve as conduits to regenerate nerves severed in accidents or blood vessels damaged by disease.

26 Feb 2009

Endovascular repair results in decrease of total aneurysm deaths

Elective repair for abdominal aortic aneurysms (AAA) is on the rise, yet total AAA- related deaths continue to decline since the introduction of endovascular repair (EVAR), according to an ongoing, long-term research report from Beth Israel Deaconess Medical Center in Boston.

26 Feb 2009

VIA Pharmaceuticals awarded new patent on lead compound VIA-2291

VIA Pharmaceuticals, Inc. has announced the issuance of United States Patent No. 7,495,024 entitled "Phenylalkyl N-Hydroxyureas for Combating Atherosclerotic Plaque", covering the use of VIA's lead compound, VIA-2291, for the treatment of atherosclerosis.

25 Feb 2009

Plasminogen activator inhibitor type-1 -- a potential link between heart failure and diabetes

Researchers at the University of Vermont Cardiovascular Research Institute, Colchester, Vermont have found that increased expression in the heart of plasminogen activator inhibitor type-1 (PAI-1) is profibrotic.

24 Feb 2009

Metastasis-promoting protein identified; could provide a prognostic test or target for breast cancer

Tumors that are about to progress and metastasize go through a process also seen in normal embryonic development, known as the epithelial to mesenchymal transition (EMT).

23 Feb 2009

Back from the dead twice

“I died twice,” says a teary-eyed DeWayne Lark, “If I didn't believe in miracles before, I believe in them now.”

20 Feb 2009

GlaxoSmithKline starts phase III trial of Syncria (albiglutide) type 2 diabetes medication

GlaxoSmithKline has announced initiation and dosing of the first patient of the Phase III clinical trial programme to evaluate the efficacy, safety and tolerability of the investigational GLP-1 (Glucagon-like peptide 1) agonist Syncria (albiglutide) in men and women with type 2 diabetes.

18 Feb 2009

White patients benefit more than blacks in surviving surgical complications at teaching hospitals

Elderly patients who undergo surgery at teaching-intensive hospitals have better survival rates than at nonteaching hospitals, but these better survival rates apparently occur in white patients, not black patients.

17 Feb 2009

Survival after surgical complications appears better at teaching hospitals for whites but not blacks

Survival after surgery appears higher at teaching hospitals than at non-teaching hospitals, but this benefit is experienced by white patients and not black patients, according to a report in the February issue of Archives of Surgery.

17 Feb 2009

Higher blood sugar levels linked to lower brain function in diabetics

Results of a recent study conducted by researchers at Wake Forest University Baptist Medical Center and colleagues show that cognitive functioning abilities drop as average blood sugar levels rise in people with type 2 diabetes.

16 Feb 2009

Avosentan shows prmoise for diabetic kidney disease

A new drug called avosentan significantly lowers urinary protein excretion-an important marker of kidney disease progression-in patients with diabetic kidney disease, according to an international clinical trial appearing in the March 2009 issue of the Journal of the American Society Nephrology (JASN).

16 Feb 2009

New method to stimulate immune system may be effective at reducing amyloid burden in Alzheimer?s

Researchers at NYU Langone Medical Center have discovered a novel way to stimulate the innate immune system of mice with Alzheimer's disease (AD) - leading to reduced amyloid deposits and the prevention of Alzheimer's disease related pathology - without causing toxic side effects.

15 Feb 2009

Vascular News and Research

New tissue engineering technique may help stem cells generate solid organs

Angiogenesis inhibitors, study points to limitations, solutions

New study finds increased prevalence of left-handedness in children with facial development disorder

The obesity paradox

Spun-sugar filaments show potential for regenerating nerves

Endovascular repair results in decrease of total aneurysm deaths

VIA Pharmaceuticals awarded new patent on lead compound VIA-2291

Plasminogen activator inhibitor type-1 -- a potential link between heart failure and diabetes

Metastasis-promoting protein identified; could provide a prognostic test or target for breast cancer

Back from the dead twice

GlaxoSmithKline starts phase III trial of Syncria (albiglutide) type 2 diabetes medication

White patients benefit more than blacks in surviving surgical complications at teaching hospitals

Survival after surgical complications appears better at teaching hospitals for whites but not blacks

Higher blood sugar levels linked to lower brain function in diabetics

Avosentan shows prmoise for diabetic kidney disease

New method to stimulate immune system may be effective at reducing amyloid burden in Alzheimer?s

Higher blood sugar levels linked to lower brain function in diabetics, study shows

Researcher develops method to combat congenital heart disease in children

New understanding of blinding degenerative eye conditions

Heart drug improve learning and memory in middle-aged rats

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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