Genes News and Research

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Tumor DNA in spinal fluid can help track children with aggressive brain tumors

For many cancers, doctors are increasingly looking to the DNA that solid tumors shed into the blood stream to help with diagnosis and monitoring. But brain cancer has been a different story thanks to the natural blockade created by the blood-brain barrier.

22 Oct 2020

Study may help develop effective therapeutic strategies against COVID-19

People have different susceptibilities to SARS-CoV-2, the virus behind the COVID-19 pandemic, and develop varying degrees of fever, fatigue, and breathing problems -- common symptoms of the illness. What might explain this variation?

22 Oct 2020

Tryptophan found in turkeys can accelerate intestinal healing in people with celiac disease

People with celiac disease may find themselves more comfortable with extra Thanksgiving turkey dinners.An international team of researchers led by McMaster University has found that tryptophan, an amino acid present in high amounts in turkey, along with some probiotics, may help them heal and respond better to a gluten-free diet.

22 Oct 2020

Researchers assess molecular basis of SARS-CoV-2 severity and poor outcomes in lung disease

A recent study published on the preprint server bioRxiv in October 2020 shows that in patients with chronic lung disease, the pattern of gene expression in the different types of cell changes such that the lung epithelium is prepared to tackle SARS-CoV-2 infection. Also, the altered gene programs have an impact on the immune response.

22 Oct 2020

SARS-CoV-2 mutations dictate severity of COVID-19 disease

A recent study by researchers from Semmelweis University and Pazmany Peter Catholic University in Budapest, Hungary, published on the preprint server medRxiv in October 2020, shows the relationship of specific mutations on the disease's outcome.

22 Oct 2020

Moffitt researchers find immune-oncologic differences in prostate tumors of African American men

Prostate cancer is the most common type of cancer among American men after skin cancer, but the disease does not affect all races equally.

21 Oct 2020

Scientists develop a way to accurately detect and monitor common pediatric brain cancer

A team of scientists at Texas A&M University, Baylor College of Medicine and Texas Children's Hospital have developed a way to more accurately both detect and monitor a common type of pediatric brain cancer, setting the stage for giving clinicians a real-time view into how the cancer responds to treatment.

21 Oct 2020

Study characterizes biochemical mechanism of cancer-linked enzyme

A new study led by scientists at IUPUI and Indiana University Bloomington is the first to describe a biochemical mechanism that increases the activity of a molecule whose presence is observed in many types of cancer.

21 Oct 2020

UCLA researchers discover compound that stimulates muscle cells in mice

UCLA researchers have identified a compound that can reproduce the effect of exercise in muscle cells in mice. The findings are published in the journal Cell Reports Medicine.

21 Oct 2020

Protein delivery to the testes restores male fertility in mice

According to the Mayo Clinic, about 15% of couples are infertile, and male infertility plays a role in over one-third of these cases.

21 Oct 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020

Scientists may be able to prevent cancer by controlling the ANP32E and H2AZ proteins

Someday, scientists may be able to prevent cancer by controlling two proteins that operate deep inside the quagmire of epigenetic cell fate transitions, a new paper suggests.

21 Oct 2020

SARS-CoV-2 hijacks mitochondria

An important phase of the viral protein translation relies on the mitochondrial translation machinery. Towards this goal, the molecular mechanism involved in the SARS-CoV-2 entry into human cells is studied by Zhenguo Cheng et al.

21 Oct 2020

Study shows ssRNA encapsidation results in stabilization of the Ebola virus nucleocapsid

The Ebola virus causes a serious infection with a mortality rate between 50% and 90%. Nucleoproteins in the virus assemble into a helical arrangement and encapsulate a single stranded RNA genome, ssRNA, to form a rodlike complex known as a nucleocapsid, which is critical to the function of the virus.

21 Oct 2020

Researchers find distinct effects of adversity in the genomes of men than women born preterm

Researchers at McMaster University have found distinct effects of adversity early in life in the genomes of men compared to women who were born extremely preterm.

21 Oct 2020

Researchers explore SARS-CoV-2 at single cell resolution in human airway epithelial cells

The cellular tropism of the SARS-CoV-2 virus affects several aspects of infection, such as the spread of the virus within and between hosts, tissue pathology, immune control mechanisms, and the response to treatment with promising antiviral drugs.

21 Oct 2020

Scientists show why zebra finches have problems with reproduction

In birds and other species alike, pairs can face considerable difficulties with reproduction. Scientists at the Max Planck Institute for Ornithology in Seewiesen have now shown in an extensive analysis of 23,000 zebra finch eggs that infertility is mainly due to males, while high embryo mortality is more a problem of the females.

20 Oct 2020

Precision epidemiology could help explain variability in COVID-19 symptoms

Researchers from National Taiwan University have presented a multi-omics view of how mutations in angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) affect infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and progression of coronaviruses disease 2019 (COVID-19).

20 Oct 2020

Researchers study the role of cannabinoids in learning

Cannabinoids have a strong influence on how our brains work and how we behave. Many people are only aware of the recreational aspect of cannabinoids.

20 Oct 2020

Study helps restore retinal and visual functions of mice models of inherited retinal disease

A breakthrough study, led by researchers from the University of California, Irvine, results in the restoration of retinal and visual functions of mice models suffering from inherited retinal disease.

20 Oct 2020

Genes News and Research

Tumor DNA in spinal fluid can help track children with aggressive brain tumors

Study may help develop effective therapeutic strategies against COVID-19

Tryptophan found in turkeys can accelerate intestinal healing in people with celiac disease

Researchers assess molecular basis of SARS-CoV-2 severity and poor outcomes in lung disease

SARS-CoV-2 mutations dictate severity of COVID-19 disease

Moffitt researchers find immune-oncologic differences in prostate tumors of African American men

Scientists develop a way to accurately detect and monitor common pediatric brain cancer

Study characterizes biochemical mechanism of cancer-linked enzyme

UCLA researchers discover compound that stimulates muscle cells in mice

Protein delivery to the testes restores male fertility in mice

New DNA-cutting tool could advance gene editing for novel treatments

Scientists may be able to prevent cancer by controlling the ANP32E and H2AZ proteins

SARS-CoV-2 hijacks mitochondria

Study shows ssRNA encapsidation results in stabilization of the Ebola virus nucleocapsid

Researchers find distinct effects of adversity in the genomes of men than women born preterm

Researchers explore SARS-CoV-2 at single cell resolution in human airway epithelial cells

Scientists show why zebra finches have problems with reproduction

Precision epidemiology could help explain variability in COVID-19 symptoms

Researchers study the role of cannabinoids in learning

Study helps restore retinal and visual functions of mice models of inherited retinal disease

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