Angioplasty News and Research

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In angioplasty procedures, a balloon is fed through a catheter and used to prop open an artery that has become narrowed or blocked. In cases where stenting is appropriate, a stent mounted on a balloon is inserted and inflation of the balloon expands the stent against the blocked artery wall to hold the vessel open. The balloon is then deflated and the catheter is withdrawn. Stent treatment of arteries holds them open and improves blood flow to the heart. In cases where post-dilatation is needed, a high-pressure balloon is inflated inside a stent to help better place the stent against the vessel wall.

The role played by drug-eluting stents in reducing acute myocardial infarction

The safety debate about drug-eluting stents (DES) is still ongoing. In these times of uncertainty about DES safety, the study has shown that DES markedly improve long-term survival compared to modern bare-metal stents (BMS) implantation in patients with acute ST-segment elevation myocardial infarction (STEMI). In our four year investigation, DES demonstrated a significant reduction of mortality in this sick patient subset.

2 Sep 2008

Factor Xa inhibitor Apixaban and antiplatelet therapy after acute coronary syndrome

Data from a phase II study of an investigational drug designed to block formation of blood clots show potential for added protection against a second heart attack or stroke among patients who are already taking state-of-the-art prevention therapy.

2 Sep 2008

Overcoming poor response to standard oral antiplatelet agents

Existing practice surrounding many cardiovascular medications, including anti-hypertensive and lipid-lowering agents, is based on the evaluation of response to therapy. In cases where ideal therapeutic targets (which have been identified through several previous studies) are not met in the single individual, there is evidence to support the need to intensify standard treatment so as to achieve better control of the cardiovascular risk factor under treatment (e.g. blood pressure or cholesterol levels) as this translates into a better outcome.

2 Sep 2008

Researchers say heart bypass a better option than drug-eluting stents

Major clinical research has found that for many patients with clogged arteries, bypass surgery is a better option than drug-eluting stents.

2 Sep 2008

Drug eluting stents: New elements in the debate

Results announced at the 2006 ESC meeting in Barcelona questioned the long-term safety of drug eluting stents (DES) and sparked intense discussion.

31 Aug 2008

Some hospitals require insured patients to make larger upfront payments for elective procedures, surgeries

The South Florida Sun-Sentinel on Tuesday examined how across the U.S., "some insured patients are being asked by hospitals to pay larger portions of their bills upfront -- and sometimes hospitals will not do the procedures until they get their copayments."

28 Aug 2008

Drug-releasing coronary artery stent use linked with decrease in procedures to unblock coronary arteries

The widespread adoption of the use of drug-releasing coronary artery stents into routine practice is associated with a decrease in the need for repeat procedures to unblock coronary arteries and also do not appear to increase the risk of death, compared to bare-metal stents, according to a study in the June 25 issue of JAMA, the Journal of the American Medical Association

24 Jun 2008

New way to limit gene transfer and expression

Researchers from Northwestern University and Texas A & M University have discovered a new way to limit gene transfer and expression to specific tissues in animals.

23 Jun 2008

Chinese red yeast rice reduces repeat heart attacks

A clinical study on patients who have suffered a heart attack found that a partially purified extract of Chinese red yeast rice, Xuezhikang (XZK), reduced the risk of repeat heart attacks by 45%, revascularization (bypass surgery/angioplasty), cardiovascular mortality and total mortality by one-third and cancer mortality by two-thirds.

9 Jun 2008

Increased screening may better predict those at higher risk for heart disease

Adding noninvasive imaging to current risk-assessment protocols may identify more people who are at risk of developing heart disease, UT Southwestern Medical Center researchers have found.

27 May 2008

Increased screening may better predict those at higher risk for heart disease

Adding noninvasive imaging to current risk-assessment protocols may identify more people who are at risk of developing heart disease, UT Southwestern Medical Center researchers have found.

26 May 2008

Bivalirudin improves net clinical outcomes and increases survival in heart attack patients

A study led by Gregg W. Stone, M.D., professor of medicine at Columbia University Medical Center/NewYork-Presbyterian and chairman of the Cardiovascular Research Foundation, has shown that heart attack patients who were administered the direct thrombin inhibitor bivalirudin during primary angioplasty had a reduced rate of adverse clinical events, a lower rate of major bleeding, and a lower mortality rate than those who were treated with a regimen of heparin and glycoprotein IIb/IIIa inhibitors (GPI).

26 May 2008

Beta blockers after surgery more risky than beneficial

The results of new research has shown that patients given high doses of beta blocker drugs following non-cardiac surgery were more likely to have a stroke or die. However they were less likely to suffer a heart attack.

13 May 2008

The gender gap is alive and well in heart disease

... a new international study finds, with women differing from men on everything from symptoms to treatment in both heart attack and severe chest pain.

6 May 2008

Autonomous robot surgery a step closer

The day may be getting a little closer when robots will perform surgery on patients in dangerous situations or in remote locations, such as on the battlefield or in space, with minimal human guidance.

6 May 2008

Women lag in heart attack care, study finds

The gender gap is alive and unwell in heart disease, a new international study finds, with women differing from men on everything from symptoms to treatment in both heart attack and severe chest pain.

6 May 2008

Cordis Corporation launches new peripheral angioplasty balloon catheters

Cordis Corporation announced today the U.S. launch of the SLEEK and SAVVY Long PTA Balloon Dilatation Catheters, its most advanced percutaneous transluminal angioplasty (PTA) balloon catheters.

5 May 2008

Drug-releasing stent shows promise for improving outcomes in patients with coronary artery disease

For patients who underwent angioplasty to open narrowed coronary arteries, the use of stents releasing the drug everolimus reduced the rate of renarrowing of the arteries and significantly reduced the risk of major cardiac events, compared to the widely-used paclitaxel-releasing stents, according to a study in the April 23/30 issue of JAMA, the Journal of the American Medical Association.

22 Apr 2008

Patients arriving at hospitals in daytime hours get faster, better care compared to off hours

Patients hospitalized with heart attacks tend to get faster and more comprehensive care if they arrive during daytime hours, according to a report in Circulation: Journal of the American Heart Association.

21 Apr 2008

Angina drug ranolazine potentially useful against heart rhythm disorders

A recently approved angina drug may also represent a powerful new treatment for a rare hereditary syndrome that places teens at risk for sudden cardiac death, according to research presented on April 1st at the 57th Annual Scientific Sessions of the American College of Cardiology (ACC) in Chicago.

9 Apr 2008