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NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Adults with chronic pain who participated in New York State's (NYS) Medical Cannabis Program were significantly less likely to require prescription opioids, according to a new study published today in JAMA Internal Medicine and led by researchers at Albert Einstein College of Medicine and Montefiore Health System.

8 Dec 2025

Targeted approach of immunotherapy improves sepsis outcomes

Immunotherapy for sepsis is effective when doctors tailor the treatment precisely to the patient's immune system condition.

8 Dec 2025

JAX wins $30 million contract to create computational "digital twins" of the human heart

Developing new drugs is one of the riskiest and most expensive endeavors in science. Today, The Jackson Laboratory (JAX) announced a bold initiative to improve that trajectory, powered by an up to $30 million contract from the Advanced Research Projects Agency for Health (ARPA-H) Computational ADME-Tox and Physiology Analysis for Safer Therapeutics (CATALYST) program.

8 Dec 2025

New combination treatment offers significant benefits for people with recurring grade 3 astrocytoma

Huntsman Cancer Institute at the University of Utah (the U) participated in a clinical trial that found that a new combination treatment plan helped people with recurring grade 3 astrocytoma, an aggressive form of brain cancer, live longer.

8 Dec 2025

Evidence grows for pirtobrutinib as a safer and effective alternative for CLL and SLL

Pirtobrutinib, a non-covalent Bruton tyrosine kinase (BTK) inhibitor, met the primary endpoint for non-inferiority in terms of overall response rate in the first head-to-head comparison with ibrutinib, a covalent BTK inhibitor.

7 Dec 2025

Many families of children with leukemia face significant financial hardship during treatment

Nearly a third of families with children receiving chemotherapy for acute lymphoblastic leukemia (ALL) – the most common pediatric cancer – develop serious financial difficulties during their child's treatment, including losing 25% or more of their household income and struggling to cover the costs of basic living expenses such as housing, food, and utilities.

7 Dec 2025

Study reveals how viral social interactions shape resistance to antivirals

Interactions among viruses can help them succeed inside their hosts or impart vulnerabilities that make them easier to treat. Scientists are learning the ways viruses mingle inside the cells they infect, as well as the consequences of their socializing.

5 Dec 2025

$New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer$

New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer

A new targeted alpha therapy is showing promise for patients whose thyroid cancer no longer responds to radioactive iodine, the standard beta-emitting treatment. In a first-in-human study, investigators found that a single dose of the alpha-emitting radionuclide 211At (astatine) was both well-tolerated and effective, achieving disease control without molecularly targeted drugs.

5 Dec 2025

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with targeted therapies.

5 Dec 2025

New combination treatment helps people with recurring grade 3 astrocytoma, trial shows

5 Dec 2025

Chronic kidney disease accelerates cognitive decline through heart-brain pathways

A new study published in the American Journal of Physiology - Heart and Circulatory Physiology reveals that chronic kidney disease (CKD) accelerates cognitive decline through interconnected damage to the heart and brain-and that these pathways differ markedly between men and women.

4 Dec 2025

New drug combination shows promise for overcoming resistance in ovarian cancer

Researchers at the University of Colorado Cancer Center have discovered a novel therapy combination that could offer new hope to ovarian cancer patients who do not respond to existing treatments.

4 Dec 2025

University of Iowa research finds an effective therapy for rare kidney disease in children

A rare and life-threatening kidney disease in children finally has an effective therapy, thanks in large part to pioneering research and clinical leadership from University of Iowa Health Care Stead Family Children's Hospital.

4 Dec 2025

Preloading Instacart online grocery carts with healthy ingredients could help improve the diets of families

University at Buffalo researchers have shown that preloading Instacart online grocery carts with healthy ingredients could be a useful tool for improving the diets of families with young kids at risk for obesity.

4 Dec 2025

Breast density alerts may cause confusion and raise anxiety among women

New research by experts at the University of Sydney shows that breast density notification is leaving some women confused and anxious about their breast health.

3 Dec 2025

New analysis reveals fundamental flaws in widely used measures of biological aging

A landmark review published today in Genomic Psychiatry challenges researchers to fundamentally reconsider how the field measures and conceptualizes biological aging.

3 Dec 2025

Prehabilitation helps reduce disability after surgery in frail older adults

A large clinical trial published in JAMA Surgery shows that prehabilitation (also called prehab) can reduce disability after surgery in older adults with frailty, provided they are able to fully take part in the prehab program.

3 Dec 2025

Tai chi proves as effective as CBT for long-term insomnia relief

Researchers compare the efficacy of Tai chi with cognitive behavioral therapy for the treatment of chronic insomnia.

3 Dec 2025

SCAI and CRT launch partnership to expand innovation and training in interventional cardiology

The Society for Cardiovascular Angiography & Interventions (SCAI) and Cardiovascular Research Technologies (CRT) today announce a new collaboration to elevate the field of interventional cardiology through shared education programming, legislative activities, and future research initiatives.

2 Dec 2025

Shingles vaccine may benefit individuals already diagnosed with dementia, new study finds

An unusual public health policy in Wales may have produced the strongest evidence yet that a vaccine can reduce the risk of dementia.

2 Dec 2025

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Clinical Trial News and Research

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Targeted approach of immunotherapy improves sepsis outcomes

JAX wins $30 million contract to create computational "digital twins" of the human heart

New combination treatment offers significant benefits for people with recurring grade 3 astrocytoma

Evidence grows for pirtobrutinib as a safer and effective alternative for CLL and SLL

Many families of children with leukemia face significant financial hardship during treatment

Study reveals how viral social interactions shape resistance to antivirals

New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

New combination treatment helps people with recurring grade 3 astrocytoma, trial shows

Chronic kidney disease accelerates cognitive decline through heart-brain pathways

New drug combination shows promise for overcoming resistance in ovarian cancer

University of Iowa research finds an effective therapy for rare kidney disease in children

Preloading Instacart online grocery carts with healthy ingredients could help improve the diets of families

Breast density alerts may cause confusion and raise anxiety among women

New analysis reveals fundamental flaws in widely used measures of biological aging

Prehabilitation helps reduce disability after surgery in frail older adults

Tai chi proves as effective as CBT for long-term insomnia relief

SCAI and CRT launch partnership to expand innovation and training in interventional cardiology

Shingles vaccine may benefit individuals already diagnosed with dementia, new study finds

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