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Rapid heart rate changes predict response to magnetic brain stimulation in depression

Researchers led by Dr. Roberto Goya-Maldonado at the University Medical Center Göttingen have identified a rapid physiological marker that predicts which patients with major depression will respond to magnetic brain stimulation therapy.

14 Oct 2025

Mother's voice promotes development of language pathways in preemies’ brains

Hearing the sound of their mother's voice promotes development of language pathways in a premature baby's brain, according to a new Stanford Medicine-led study.

14 Oct 2025

Trial examines slow-tempo music as a strategy to reduce delirium in critically ill older adults

A multi-center randomized controlled trial with critically ill adults aged 50 years and older admitted to intensive care units (ICUs) found that twice-daily slow-tempo music (60 to 80 beats per minute) did not shorten the duration of delirium or coma, or reduce delirium severity, pain or anxiety compared with a silence-track control.

13 Oct 2025

HEPA purifiers do not fully reduce classroom viral exposure

In a secondary analysis of a study of 200 classrooms, Mass General Brigham researchers found respiratory viral exposures were still high in those with HEPA purifiers, suggesting additional interventions are needed.

10 Oct 2025

Understanding the impact of chikungunya on children

Chikungunya is a vector-borne disease that affects both adults and children. While global efforts are ongoing to tackle chikungunya in adults, progress in addressing pediatric chikungunya remains inadequate.

10 Oct 2025

Breakthrough in cancer therapy targets key protein interaction to suppress tumors

Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS, and a key pathway for tumor growth.

9 Oct 2025

The ISSCR releases new resource to accelerate the development of PSC-derived therapies

The International Society for Stem Cell Research (ISSCR) is proud to announce the release of Best Practices for the Development of Pluripotent Stem Cell-Derived Cellular Therapies, a comprehensive, interactive new resource designed to accelerate the translation of human pluripotent stem cell (PSC)-derived therapies into clinical trials and commercial use.

9 Oct 2025

Quitting smoking after cancer diagnosis significantly extends survival

Around 25% of people with cancer in the U.S. are active smokers when they are diagnosed, and studies have found that many of them continue to smoke during treatment.

9 Oct 2025

Engineered virus therapy triggers powerful immune responses in glioblastoma

A new study led by Break Through Cancer's Accelerating Glioblastoma (GBM) Therapies Through Serial Biopsies TeamLab has revealed that an engineered virus therapy, CAN-3110, triggered powerful immune responses deep inside glioblastoma tumors that were invisible to standard imaging like MRI, according to early analyses of two patients with recurrent GBM.

9 Oct 2025

University Of California researchers, patients wary of Trump cuts even as some dollars flow again

In August, an 80-year-old woman walked into the emergency room at Ronald Reagan UCLA Medical Center. She was lucid but experiencing a stroke.

9 Oct 2025

Repeated sampling offers insight into glioblastoma therapy response

A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass General Brigham Cancer Institute, found that serially testing tumor samples can help detect when a cancer treatment is activating the immune system in recurrent glioblastoma (GBM), even when traditional imaging measures cannot.

8 Oct 2025

Engineered Salmonella therapy delivers immune payloads to combat cancer

A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled "ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response."

8 Oct 2025

New dual-target vaccine shows promise against typhoid and Salmonella

Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health (CVD) have completed a successful Phase 1 clinical trial of a novel vaccine designed to protect against both typhoid fever and invasive non-typhoidal Salmonella--two major causes of illness and death among children in sub-Saharan Africa.

8 Oct 2025

Engineered CAR-NK cells show enhanced cancer killing and immune evasion

One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be programmed to attack cancer cells.

8 Oct 2025

Whole genome sequencing may guide care for thousands of breast cancer patients

Whole genome sequencing offered to breast cancer patients is likely to identify unique genetic features that could either guide immediate treatment or help match patients to clinical trials for over 15,000 women a year, say scientists at the University of Cambridge.

7 Oct 2025

Unlocking the mysteries of treatment-resistant prostate cancer

Advances in prostate cancer early detection and treatment have improved outcomes in men diagnosed with the disease.

7 Oct 2025

New drug combination could delay the progression of advanced prostate cancer

A new drug combination could significantly delay the progression of a life-threatening form of prostate cancer in men with specific genetic mutations, finds a major international trial led by UCL researchers.

7 Oct 2025

New ASPIRE trial tests chemotherapy combination for advanced prostate cancer

The Alliance for Clinical Trials in Oncology has launched the ASPIRE trial-a large-scale, Phase III clinical study investigating whether adding chemotherapy to current standard treatments can extend survival for men living with advanced prostate cancer.

6 Oct 2025

DKMS advances blood cancer research with groundbreaking ASAP study

The selection of patients for allo-HSCT and the best approach to bridging patients to transplantation is continuously discussed by experts.

6 Oct 2025

New intervention improves pediatricians' ability to counsel families on early peanut introduction

Results from a randomized clinical trial published in Pediatrics show that pediatricians who received targeted educational and clinical decision-support tools were significantly more likely to advise parents to introduce peanut-containing foods early – an approach recommended by national prevention guidelines but often underused in practice.

6 Oct 2025