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Study reveals how devastating mitochondrial diseases strike families without any previous history

Researchers have shown for the first time how children can inherit a severe - potentially fatal - mitochondrial disease from a healthy mother.

15 Jan 2018

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has approved LYNPARZA (olaparib) for use in patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer who have been previously treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting.

12 Jan 2018

IVF just as likely to result in live birth when frozen embryos are used

Women who use frozen embryos for in vitro fertilization (IVF) have the same chance of ongoing pregnancy and giving birth as those who have IVF, finds study.

11 Jan 2018

Identical twins share additional level of molecular similarity

An international group of researchers has discovered a new phenomenon that occurs in identical twins: independent of their identical genes, they share an additional level of molecular similarity that influences their biological characteristics.

9 Jan 2018

Bioengineers reveal how to recreate complex folded shapes from living tissue

Many of the complex folded shapes that form mammalian tissues can be recreated with very simple instructions, UC San Francisco bioengineers report December 28 in the journal Developmental Cell.

30 Dec 2017

$Study uncovers genomic targets in refractory neuroblastoma$

Study uncovers genomic targets in refractory neuroblastoma

Neuroblastoma (NB) is the most common solid tumor found in children. It starts in some very early forms of nerve cells found in the embryo or fetus.

28 Dec 2017

Researchers find progenitor cells for all the heart's components, except right ventricle

Progenitor cells - undifferentiated cells that later become specified - for all the heart's components, except for the right ventricle, have been found by Hiroshima University researchers and detailed in a paper published in Nature Communications.

26 Dec 2017

Study shows vital role for maternally inherited gene in embryonic development

A new study indicates an essential role for a maternally inherited gene in embryonic development. The study found that zebrafish that failed to inherit specific genetic instructions from mom developed fatal defects earlier in development, even if the fish could make their own version of the gene.

18 Dec 2017

Researchers identify previously unknown functions of natural killer cells in the womb

For the first time the functions of natural killer cells in the womb have been identified. Researchers at the University of Warwick and University Hospitals Coventry and Warwickshire NHS Trust have discovered the role that they play in preparing the womb for pregnancy.

14 Dec 2017

Researchers unravel novel mechanism of estrogen action on heart physiology

Estrogens are powerful hormones important for the formation and function of the nervous, reproductive and cardiovascular systems.

6 Dec 2017

Study reveals gene linked to metastatic melanoma

A study by Craig J. Ceol, PhD, assistant professor of molecular medicine at the University of Massachusetts Medical School, has revealed a protein active during early embryo development called GDF6 plays a primary role in metastatic melanoma.

4 Dec 2017

FDA grants approval to first biosimilar for treatment of patients with breast, stomach cancers

The U.S. Food and Drug Administration today approved Ogivri (trastuzumab-dkst) as a biosimilar to Herceptin (trastuzumab) for the treatment of patients with breast or metastatic stomach cancer (gastric or gastroesophageal junction adenocarcinoma) whose tumors overexpress the HER2 gene (HER2+).

4 Dec 2017

INRS researchers evaluate how chemotherapy among men affects health of future generations

How do cancer and cancer treatments affect the reproductive function of men? Can this affect the health of their direct descendants and subsequent generations? To get a clear picture, INRS researchers evaluate the current state of knowledge on this public health issue in a review article appearing in the journal Gynécologie Obstétrique & Fertilité.

30 Nov 2017

USC researchers propose rules for making ribs

Scientists from the USC Stem Cell lab of Francesca Mariani recently shared a recipe for ribs, and it doesn't even require barbecue sauce.

29 Nov 2017

Treatment of abnormal vaginal microbiota prior to embryo transfer may improve reproductive outcomes

High levels of two specific vaginal bacteria (Atopobium vaginae and Gardnerella vaginalis) serve as diagnostic markers of an abnormal vaginal microbiota that might cause impaired implantation and subsequent poor reproductive outcome.

28 Nov 2017

Live births more likely to occur in women with sufficient vitamin D, research finds

Researchers are calling for a randomized clinical trial to investigate the potential role of vitamin D supplementation in improving live birth rates following assisted reproduction treatment.

15 Nov 2017

Scientists improve resolution of optical microscope using mirrored coverslip and computer algorithms

Researchers from the National Institutes of Health and the University of Chicago improved the speed, resolution, and light efficiency of an optical microscope by switching from a conventional glass coverslip to a reflective, mirrored coverslip and applying new computer algorithms to process the resulting data.

13 Nov 2017

Penn Medicine to conduct Northeast’s first clinical trial of uterine transplants

Penn Medicine will conduct the Northeast's first clinical trial of uterine transplants, to provide women with Uterine Factor Infertility (UFI) - an irreversible form of female infertility that affects as many as 5 percent of women worldwide and 50,000 women in the United States - with a new path to parenthood.

7 Nov 2017

Studying the nanomechanical properties of aging and cancerous cells using AFM

An interview with Prof. Igor Sokolov, Tufts University conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 31 Oct 2017

Study supports that weekend work may not be needed for most IVF/ICSI treatments

It's unclear whether there is a need to retrieve a woman's eggs on weekends, in connection with in vitro fertilization/intracytoplasmatic sperm injection (IVF/ICSI) treatment in couples wishing to conceive.

27 Oct 2017