Antibodies News and Research

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Anti-CPP presence in bloodstream of RA patients correlates with drug response

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that the presence of an antibody (anti-CPP ) in the bloodstream of patients with rheumatoid arthritis (RA) correlates with response to different drug treatments.

10 Jun 2016

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that when antibodies develop in response to the biological treatment Remicade (infliximab), they also cross-react with the biosimilar of infliximab (CT-P13: Inflectra or Remsima).

10 Jun 2016

Dr. Pinchas Tsukerman earns prestigious Kaye Innovation Award for research on cancer immunotherapy

The importance of the body's immune system in protecting against the creation of cancerous tumors has been known for a long time. But despite the existence of a competent immune system, some individuals develop tumors, in part because tumors have ways to evade destructive immunity or induce immune-suppression.

9 Jun 2016

Study provides insights into new pathways to generate universal vaccine against influenza viruses

Diverse antibodies induced in humans by vaccination with an avian influenza virus vaccine may offer broader, more durable protection against multiple strains of influenza than today's vaccines typically provide, according to a study led by Florian Krammer, PhD, Assistant Professor in the Department of Microbiology at the Icahn School of Medicine at Mount Sinai, and Patrick Wilson, PhD, Associate Professor in the Department of Medicine at the University of Chicago.

9 Jun 2016

Migraine drug has quick onset of action

The drug TEV-48125, shown to be effective for chronic migraine in a phase II trial, appears to work within 3 to 7 days of injection, researchers report.

9 Jun 2016

Scientists develop non-toxic transplantation procedure using antibodies to target blood stem cells in mice

Harvard Stem Cell Institute scientists have taken the first steps toward developing a treatment that would make bone marrow - blood stem cell - transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and AIDS.

7 Jun 2016

Tanaka develops world's first kit to directly detect ZIKA virus in blood

Tanaka Holdings Co., Ltd. announced today that Tanaka Kikinzoku Kogyo K.K., which operates the Tanaka Precious Metals manufacturing business, has developed the world's first kit able to directly detect the ZIKA virus in blood. The kit is capable of rapid ZIKV detection in just 10 to 15 minutes.

7 Jun 2016

Eculizumab drug provides new hope for kidney failure patients

Surgeons at the University of Illinois Hospital & Health Sciences System have — for the first time — used an orphan drug to prevent rejection of a kidney transplanted from a living donor with a mismatched blood type.

7 Jun 2016

Scientists use X-rays to study how eculizumab prevents immune system from damaging kidney tissue

In collaboration with Alexion Pharmaceuticals, Inc., scientists from Aarhus University have used X-rays to understand how the therapeutic antibody eculizumab prevents our immune system from destroying red blood cells and damaging kidney tissue.

6 Jun 2016

Improved research tool may open door to effective HIV vaccine designs

Vaccines are usually medicine's best defense against the world's deadliest microbes. However, HIV is so mutable that it has so far effectively evaded both the human immune system and scientists' attempts to make an effective vaccine to protect against it.

6 Jun 2016

Giving chemotherapy after radiotherapy delays rare brain tumour growth

GIVING chemotherapy after radiotherapy delays further growth of a rare type of brain tumour, increasing the number of patients alive at five years from 44 per cent to 56 per cent.

6 Jun 2016

UZH scientists identify new class of protein compounds to treat HER2-positive breast cancer

In Switzerland alone, more than 5,700 women are diagnosed with breast cancer each year, and almost 1,400 of those affected die of the disease. In many very invasive forms of breast cancer, the cells have too much of the receptor HER2 on their surface.

3 Jun 2016

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

Neuroblastoma tumors shrank, some dramatically, in 80 percent of newly diagnosed, young, high-risk patients enrolled in a Phase II clinical trial that included an experimental monoclonal antibody. The immunotherapy agent was produced on the St. Jude Children's Research Hospital campus where the study is still underway.

3 Jun 2016

New mouse model allows researchers to evaluate CD40-antibody drugs effectively

Cancer immunotherapies--drugs that work by making a patient's immune system better at spotting and destroying tumor cells--are increasingly generating headlines. A number of these drugs are now being used for the treatment of melanoma, lung, and kidney cancers, and are showing promise in clinical trials with other diseases as well.

3 Jun 2016

Maternal vaccination against influenza can reduce flu risk in newborns

Each year, influenza causes between 250,000 and half a million deaths around the world. Pregnant women and young infants have a higher risk of complications related to influenza; these complications can easily lead to death.

3 Jun 2016

Additional drug treatment options to prevent migraine may offer hope to sufferers

Preventing or shortening the duration of migraine attacks - established drug treatment options and those that could shape future therapies were discussed at the Congress of European Academy of Neurology in Copenhagen.

1 Jun 2016

New study sheds light on link between gut microbiome and the brain

Intestinal bacteria that can boost bravery or trigger multiple sclerosis: An increasing body of research results confirms the importance of the "gut-brain axis" for neurology and indicates that the triggers for a number of neurological diseases may be located in the digestive tract.

30 May 2016

SIPPET study may have implications for treatment of patients with severe hemophilia A

SIPPET, a study which involved 42 centers in 14 countries in Europe, North and South America, Africa and Asia was designed to definitively settle the long-debated question whether factor VIII concentrates from different sources (plasma-derived containing VWF or recombinant technology) differ in risk of inhibitor development in previously untreated children (PUPs) with severe hemophilia A.

28 May 2016

New hydrogel-based biochip may help in early diagnosis of bowel cancer

Researchers from the Moscow Institute of Physics and Technology, the Engelhardt Institute of Molecular Biology, the Institute of Bioorganic Chemistry and a number of other Russian research centers have developed a new method of diagnosing colorectal cancer.

27 May 2016

Malaria parasites use complement system to evade human immune response, study finds

The malaria parasite Plasmodium falciparum hijacks an immune system process to invade red blood cells, according to a study led by researchers at Penn State College of Medicine. Understanding how malaria invades the cells could lead to a more effective vaccine.

26 May 2016

Antibodies News and Research

Anti-CPP presence in bloodstream of RA patients correlates with drug response

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

Dr. Pinchas Tsukerman earns prestigious Kaye Innovation Award for research on cancer immunotherapy

Study provides insights into new pathways to generate universal vaccine against influenza viruses

Migraine drug has quick onset of action

Scientists develop non-toxic transplantation procedure using antibodies to target blood stem cells in mice

Tanaka develops world's first kit to directly detect ZIKA virus in blood

Eculizumab drug provides new hope for kidney failure patients

Scientists use X-rays to study how eculizumab prevents immune system from damaging kidney tissue

Improved research tool may open door to effective HIV vaccine designs

Giving chemotherapy after radiotherapy delays rare brain tumour growth

UZH scientists identify new class of protein compounds to treat HER2-positive breast cancer

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

New mouse model allows researchers to evaluate CD40-antibody drugs effectively

Maternal vaccination against influenza can reduce flu risk in newborns

Additional drug treatment options to prevent migraine may offer hope to sufferers

New study sheds light on link between gut microbiome and the brain

SIPPET study may have implications for treatment of patients with severe hemophilia A

New hydrogel-based biochip may help in early diagnosis of bowel cancer

Malaria parasites use complement system to evade human immune response, study finds

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