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Researchers identify new potential mechanism for age-related macular degeneration

Using laboratory-grown roundworms as well as human and mouse eye tissue, University of Maryland School of Medicine (UMSOM) researchers have identified a new potential mechanism for age-related macular degeneration - the leading cause of blindness among older adults.

13 Apr 2021

Inhibition of nsp14 methyltransferase as a potential antiviral target for SARS-CoV-2

Beyond vaccination, the broad-spectrum antiviral medication remdesivir has robust clinical evidence and is known as the best antiviral treatment to reduce severe COVID-19 infection in hospitalized patients. Research led by John F.X. Diffley of the Chromosome Replication Laboratory suggests a potential therapeutic target for treatment development is the viral RNA cap methyltransferases, essential for viral protein translation and immune evasion.

13 Apr 2021

New technology shows encouraging results for treating osteosarcoma

A preclinical study led by researchers at The University of Texas MD Anderson Cancer Center shows an antibody-drug conjugate (ADC) targeting surface protein MT1-MMP can act as a guided missile in eradicating osteosarcoma tumor cells without damaging normal tissues.

13 Apr 2021

Children less likely to spread SARS-CoV-2 than adults

A study conducted by researchers in Canada suggests that children may be less likely than adults to spread the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19).

12 Apr 2021

Real-world evidence from Israel on VOCs and SARS-CoV-2 vaccine protection

A new study by Israeli researchers tested the hypothesis that certain SARS-CoV-2 variants of concern can overcome protection conferred by Pfizer-BioNTech (BNT162b2) mRNA vaccine and found evidence of increased breakthrough rates in vaccinated individuals. The research paper is currently available on the medRxiv preprint server.

12 Apr 2021

Research may lead to a significant breakthrough in the battle against deadly brain tumors

Groundbreaking research from Tel Aviv University may lead to a significant breakthrough in the battle against deadly brain cancer.

12 Apr 2021

New test offers a simpler way to quantify the reservoir of intact viruses in HIV patients

A new test that measures the quantity and quality of inactive HIV viruses in the genes of people living with HIV may eventually give researchers a better idea of what drugs work best at curing the disease.

12 Apr 2021

Parallel Evaporator Assists Metabolomics Research

BioChromato Inc. has published an interview with the Institute of Analytical Sciences, Faculty of Pharmaceutical Sciences at the University of Fukuoka (Fukuoka, Japan) that explains how a Smart Evaporator C10 has enabled them to concentrate amino acids

From BioChromato Inc. 12 Apr 2021

Commercial assays detect mRNA-1273 and BNT162b2 vaccine-induced SARS-CoV-2 antibodies in most vaccinated participants

A recent study by researchers from Canada aimed to examine the ability of commercial assays to detect vaccine-induced antibodies and recognize the vaccination response.

12 Apr 2021

Researchers unveil new SARS-CoV-2 inhibitor that targets viral immune evasion

In a recent quest for an effective antiviral compound, UK researchers have purified a specific enzyme of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) known as nsp15 and optimized fluorescent biochemical endoribonuclease assays to screen a custom chemical library with over 5,000 commercial compounds. The study is currently available on the bioRxiv* preprint server.

11 Apr 2021

Broadly neutralizing antibodies show promise in preventing tick-borne encephalitis in mice

Tick-borne encephalitis is a disease just as nasty as it sounds. Once bitten by an infected tick, some people develop flu-like symptoms that resolve quietly but leave behind rampant neurological disease--brain swelling, memory loss, and cognitive decline.

9 Apr 2021

New biosealant therapy may help treat damaged cartilage tissue

A new biosealant therapy may help to stabilize injuries that cause cartilage to break down, paving the way for a future fix or - even better - begin working right away with new cells to enhance healing, according to a new animal-based study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

9 Apr 2021

Children may be less infectious in spreading SARS-CoV-2 to others

Children may not be as infectious in spreading SARS-CoV-2 to others as previously thought, according to new University of Manitoba-led research in CMAJ.

9 Apr 2021

Brain organoid models reveal mechanisms linked to virus-induced microcephaly

Researchers at IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences - demonstrate that different viruses can lead to brain malformations through diverse mechanisms by using human brain organoid models.

9 Apr 2021

Tiny SARS-CoV-2 protein may have big implications for future COVID-19 treatments

A tiny protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future treatments, according to a team of Penn State researchers.

9 Apr 2021

Scanning & Decoding Tube Racks Direct from Low Temperature Storage

Ziath has posted a new video that provides an easy-to-follow guide to assist scientists and technicians scanning and decoding sample tube racks direct from low-temperature storage.

9 Apr 2021

Study shows Urolithin A as a potent enhancer of muscle function in mice with muscular dystrophy

Progression of Duchenne Muscle Dystrophy (DMD) can be delayed in mice by supplementing their diets with Urolithin A, according to new results reported today.

9 Apr 2021

Study shows how melanoma cells evade detection and destruction by immune cells

A dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, including melanoma.

9 Apr 2021

Study explains future ethical implications of brain organoid research

Stem cell research has allowed medicine to go places that were once science fiction. Using stem cells, scientists have manufactured heart cells, brain cells and other cell types that they are now transplanting into patients as a form of cell therapy.

9 Apr 2021

COVID-19 pandemic increases risk of suicides in veterans wtih post-traumatic stress disorder

The U.S. military veteran population is known to have abnormally high rates of suicide, so health officials have been concerned that the COVID-19 pandemic might elevate risk of psychiatric disorders, particularly among those suffering from post-traumatic stress and related disorders.

9 Apr 2021

Laboratory News and Research

Researchers identify new potential mechanism for age-related macular degeneration

Inhibition of nsp14 methyltransferase as a potential antiviral target for SARS-CoV-2

New technology shows encouraging results for treating osteosarcoma

Children less likely to spread SARS-CoV-2 than adults

Real-world evidence from Israel on VOCs and SARS-CoV-2 vaccine protection

Research may lead to a significant breakthrough in the battle against deadly brain tumors

New test offers a simpler way to quantify the reservoir of intact viruses in HIV patients

Parallel Evaporator Assists Metabolomics Research

Commercial assays detect mRNA-1273 and BNT162b2 vaccine-induced SARS-CoV-2 antibodies in most vaccinated participants

Researchers unveil new SARS-CoV-2 inhibitor that targets viral immune evasion

Broadly neutralizing antibodies show promise in preventing tick-borne encephalitis in mice

New biosealant therapy may help treat damaged cartilage tissue

Children may be less infectious in spreading SARS-CoV-2 to others

Brain organoid models reveal mechanisms linked to virus-induced microcephaly

Tiny SARS-CoV-2 protein may have big implications for future COVID-19 treatments

Scanning & Decoding Tube Racks Direct from Low Temperature Storage

Study shows Urolithin A as a potent enhancer of muscle function in mice with muscular dystrophy

Study shows how melanoma cells evade detection and destruction by immune cells

Study explains future ethical implications of brain organoid research

COVID-19 pandemic increases risk of suicides in veterans wtih post-traumatic stress disorder

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