Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

New cryoablation technique eliminates ventricular tachycardia in 94% of patients

A new technology using ultralow temperature cryoablation (ULTC) has eliminated clinical ventricular tachycardia (VT) in 94% of patients. The late-breaking science is presented at EHRA 2024, a scientific congress of the European Society of Cardiology (ESC).

8 Apr 2024

SMART trial shows comparable outcomes of two common TAVR devices in small aortic annulus patients

People with a small aortic annulus, a part of the heart's anatomy where the left ventricle meets the aorta, who underwent transcatheter aortic valve replacement (TAVR) with a supra-annular self-expanding valve saw similar clinical outcomes and superior valve performance at one year compared with those who underwent TAVR with a balloon-expandable valve, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Study: Empagliflozin shows mixed results in heart attack patients

Use of the sodium glucose cotransporter-2 (SGLT-2) inhibitor empagliflozin following a heart attack did not show a significant benefit in reducing overall heart failure hospitalizations or death from any cause, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Interatrial shunt may offer differential benefits based on heart failure type

Patients with heart failure who had a small shunt inserted between the heart's left and right atria did not see any significant benefits overall compared with those who received a placebo procedure after a median of 22 months follow-up, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Ten doctors on FDA panel reviewing Abbott heart device had financial ties with company

When the FDA recently convened a committee of advisers to assess a cardiac device made by Abbott, the agency didn't disclose that most of them had received payments from the company or conducted research it had funded — information readily available in a federal database.

8 Apr 2024

Study questions routine use of beta blockers after heart attack

Taking beta blockers after a heart attack did not significantly reduce the risk of death or a second heart attack among people with normal heart pumping ability, as indicated by an ejection fraction of 50% or higher, according to a study presented at the American College of Cardiology's Annual Scientific Session.

7 Apr 2024

Behavioral economics strategies boost daily walking by 10% in high-risk cardiovascular patients

Strategies such as earning points or small amounts of money encouraged people at high risk for heart disease or stroke to increase their daily walking by about 10% and sustain the increase for a year, according to research being presented at the American College of Cardiology's Annual Scientific Session.

7 Apr 2024

NYU Langone Heart experts unveil breakthroughs at ACC 2024

Experts from NYU Langone Heart are presenting their latest clinical findings and research discoveries during the American College of Cardiology (ACC) 2024 Annual Scientific Session & Expo, held April 6 to 8 in Atlanta.

5 Apr 2024

PeriCord bioimplants show promise in heart regeneration studies

The promising results obtained in a clinical trial with a pioneering advanced therapy drug named PeriCord, which aims to repair the heart of patients who have suffered a heart attack, confirm the feasibility of new therapies based on the application of stem cells and tissue engineering to promote the regeneration of damaged tissues.

5 Apr 2024

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

Anti-inflammatory therapy shows promise to treat patients following acute myocardial infarction

Research into the protective effects of two anti-inflammatory molecules, transforming growth factor-beta1 (TGFβ1) and Heligmosomoides polygyrus TGM (HpTGM), following heart attack found that both proteins reduced the inflammatory response within the injured heart and reduced mature scarring.

4 Apr 2024

New model predicts kidney injury risk in cancer patients on cisplatin

Researchers have developed a new model predicting severe acute kidney injury in patients treated with cisplatin, incorporating factors like hypomagnesemia to improve patient care and outcomes.

3 Apr 2024

E-cigarette use linked to increased risk of heart failure, large study finds

People who use e-cigarettes are significantly more likely to develop heart failure compared with those who have never used them, according to one of the largest prospective studies to date investigating possible links between vaping and heart failure.

2 Apr 2024

Study finds elevated sodium consumption in heart disease patients

Individuals with heart disease stand to gain the most from a low-sodium diet but, on average, consume over twice the recommended daily sodium intake, according to a study being presented at the American College of Cardiology's Annual Scientific Session.

2 Apr 2024

UVA researchers discover Y chromosome gene linked to heart failure in men

University of Virginia School of Medicine researchers have discovered a gene on the Y chromosome that contributes to the greater incidence of heart failure in men.

1 Apr 2024

Research identifies optimal body weight to reduce cardiovascular risk in diabetes patients

New research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May), identifies the optimum body weight range for adults with type 2 diabetes to minimize their risk of dying from any cardiovascular disease, including heart failure, heart disease, stroke, and chronic kidney disease.

30 Mar 2024

Polypills prove effective in reducing cardiovascular disease and mortality

A new study from researchers at Washington University Medical School in St. Louis bolsters previous findings that polypills are beneficial in preventing heart attacks and strokes and reducing deaths among people with cardiovascular risk factors, including high blood pressure and high cholesterol.

29 Mar 2024

Research highlights health risks posed by 2,6-DHNPs in drinking water

2,6-DHNPs, a group of disinfection byproducts (DBPs), are raising alarm bells for public health. These bad actors in the water world are tougher and more toxic than many other pollutants, making it hard for typical water cleaning methods to get rid of them.

29 Mar 2024

An ActRIIA fusion protein got FDA approved for PAH treatment

On March 26th, the US FDA granted approval for Merck’s WINREVAIR™ (sotatercept-csrk), marking a significant milestone in pulmonary arterial hypertension (PAH) treatment. PAH, characterized by elevated blood pressure in the arteries connecting the heart and lungs, poses a grave risk of heart failure.

From Sino Biological Inc. 28 Mar 2024

New research advocates genetic screening in early onset atrial fibrillation

Although the vast majority of clinicians do not view atrial fibrillation (AF) as a genetic disorder, a White Paper in the Canadian Journal of Cardiology, published by Elsevier, analyzes the current understanding of genetics and the role of genetic testing in AF and concludes there is an increasing appreciation that genetic culprits for potentially life-threatening ventricular cardiomyopathies and channelopathies may initially present with AF.

28 Mar 2024