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New review highlights spatial technologies in advanced brain mapping

Understanding how molecular changes shape brain function and disease requires more than measuring genes in bulk tissue.

21 Aug 2026

Wake-activated brain circuits reveal what drives the urge to sleep

Researchers identified wake-activated neurons in the median raphe and anterior medial preoptic area that track sleep pressure and help regulate when and how deeply mice sleep. Manipulating these circuits altered NREM sleep, sleep-pressure accumulation, and rebound sleep, revealing key neural mechanisms underlying mammalian sleep homeostasis.

20 Aug 2026

Glioma microenvironment emerges as key target for future therapies

The prognosis for glioma patients remains extremely poor despite aggressive multimodal standard therapy: maximal safe resection, radiotherapy, and temozolomide chemotherapy, with median survival rarely exceeding 15 to 18 months.

20 Aug 2026

Researchers maintain brain organoids for longer than ever before

An international team of researchers has maintained brain organoids, three-dimensional models of human brain tissue, for longer than ever before.

20 Aug 2026

New brain wave theory explains cognition and consciousness

A new theory, published in The Journal of Neuroscience by three scientists in The Picower Institute for Learning and Memory at MIT, offers an explanation of how the brain produces cognition and consciousness: It uses traveling waves of rhythmic neural activity to coordinate nimble neural networks with analog computations.

20 Aug 2026

Brain organoid studies on the ISS move closer to new treatments

Research using human brain organoids onboard the International Space Station International Space Station (ISS) helped lead to the clinical trial of a potential therapy for Rett syndrome, a debilitating neurological disorder in children.

20 Aug 2026

Microglial differences found in genetic and sporadic frontotemporal dementia patients

A study by the University of Eastern Finland revealed for the first time clear differences in the function and gene expression of microglial cells from patients with genetic and sporadic types of frontotemporal dementia.

20 Aug 2026

New optical control platform blocks and restores neural signaling

DGIST (President Kunwoo Lee) announced that a research team led by Professor Ji Won Um of the Center for Synapse Diversity and Specificity, Department of Brain Sciences, in collaboration with a research team led by Professor Alice Ting at Stanford University, has developed LATeNT, a novel optical control platform that uses light to block signal transmission between neurons and subsequently restore normal signaling.

19 Aug 2026

Estrogen fluctuations reshape brain connections, new study finds

A new study out of the University of Delaware shows that fluctuations in estrogen influence the brain, helping reshape connections between neurons.

18 Aug 2026

Youth-associated protein reverses age-related microglial changes in mice

Researchers at The Icahn School of Medicine at Mount Sinai have identified a role for the youth-associated protein TIMP2 in supporting the healthy function of microglia, the brain's resident immune cells.

14 Aug 2026

New microscope tracks electrical activity across the brain on the scale of milliseconds

Within the brain, neurons compute by generating electrical impulses. These signals travel throughout neurons, which are in turn connected in vast networks that control brain functions such as sensory perception, memory formation, and control of movement.

14 Aug 2026

Neuroscientists study the brain circuits mediating experience-dependent decision-making in mice

A brain must constantly cope with the highly variable, fast-paced nature of the world when trying to judge what's going on around it.

14 Aug 2026

Mouse study reveals memories survive massive loss of brain synapses

Memories can survive even after the brain temporarily loses more than half of its synaptic connections, according to a new mouse study, which challenges the long-held view that long-term memories depend on stable individual synapses.

13 Aug 2026

Astrocytes found to directly regulate memory consolidation during sleep

Research has shown that a good night's sleep has many benefits, including memory consolidation. How sleep enables the brain to strengthen memories is still not completely understood, but a new study published in Neuron reveals how astrocytes, brain cells known for supporting neurons and their functions, can directly regulate brain circuits involved in memory consolidation.

13 Aug 2026

Mitochondrial protein deficiency drives increased fat intake and obesity

Obesity is a global health concern that can contribute to diabetes, cardiovascular disease, and other metabolic disorders.

13 Aug 2026

Brain scans reveal language-specific network of neurons even during nonlinguistic tasks

The language network in your brain can be seen, even if you aren't saying a word.

13 Aug 2026

High frequency brain waves help coordinate human working memory

Research from scientists at University of California San Diego School of Medicine and collaborators has shed new light on how the human brain coordinates working memory, the process in which the brain encodes information for immediate or short-term use.

12 Aug 2026

Targeting single gene reverses developmental deficits in adult mice

Some of the symptoms of neurodevelopmental disorders (NDDs) such as autism spectrum disorder and epilepsy may result from dysfunction of certain neurons in the brain and their ability to change their properties in response to experiences-a process called experience-dependent plasticity.

12 Aug 2026

New imaging model can detect early brain changes in Huntington's disease

Researchers have shown that an imaging model can detect microstructural abnormalities in the brain associated with Huntington's disease, potentially offering a new method for monitoring disease progression and evaluating new treatments.

11 Aug 2026

Senescent brain immune cells secrete protein linked to cognitive decline

Brain-resident immune cells that have reached an old-age state called "senescence" secrete a protein that causes dysfunction in other brain cells, according to a study led by investigators at Weill Cornell Medicine.

11 Aug 2026