Small Intestine News and Research

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Breakthrough bat organoid platform sheds light on behavior of zoonotic viruses

Did you know that more than 75% of new infectious diseases affecting humans originally come from animals? Bats, in particular, are natural hosts to some of the world's most dangerous viruses, including those responsible for COVID-19 (SARS-CoV-2), MERS-CoV, influenza A, and hantavirus outbreaks.

15 May 2025

Once-daily oral treatment shows positive results in first human study for obesity treatment

A first-in-human study of an investigational once-daily oral treatment for obesity (SYNT-101) demonstrated positive preliminary data for the safe and effective redirection of nutrient absorption into the lower intestine, the weight loss and metabolic management mechanism behind gastric bypass surgery.

14 May 2025

Gut immune cells linked to worsening rheumatoid arthritis

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.

2 May 2025

High fructose diets impair brain function and appetite control, study shows

Review highlights how excessive fructose intake disrupts brain energy balance, appetite regulation, and cognitive function. Processed sources, such as sugary drinks, may overwhelm metabolic pathways and induce neuroinflammation, particularly during adolescence.

30 Apr 2025

Study shows how alcohol combined with burn trauma throws the intestinal microbiome into chaos

What happens in your gut after a night of heavy drinking and a severe burn injury? According to a new study, it might involve more than just pain and discomfort.

22 Apr 2025

Treating SIBO holistically helps patients feel better, new study finds

A 90-day real-world study in Spain shows that a comprehensive, personalized treatment for SIBO significantly improves patients’ quality of life—even when breath tests remain abnormal.

7 Apr 2025

Reprogramming the colon could be a therapeutic strategy for short bowel syndrome

Knocking out a single gene reprograms part of the large intestine to function like the nutrient-absorbing small intestine.

3 Apr 2025

Smoothies with seeds may improve glycemic control, study shows

Blending whole fruits into smoothies may reduce glycemic spikes compared to eating fruit whole or drinking juice, especially when seeds are included. Researchers urge a re-evaluation of public health guidelines that currently limit smoothie intake.

3 Apr 2025

AI matches pathologists in diagnosing celiac disease

A machine learning algorithm developed by Cambridge scientists was able to correctly identify in 97 cases out of 100 whether or not an individual had coeliac disease based on their biopsy, new research has shown.

27 Mar 2025

AI is as good as pathologists at diagnosing coeliac disease, study finds

26 Mar 2025

Mount Sinai-led research uncovers mechanisms behind Crohn's disease inflammation

A research team led by Mount Sinai has uncovered mechanisms of abnormal immune cell function that may lead to Crohn's disease, according to findings published in Science Immunology on March 21.

22 Mar 2025

Study offers new insights into the harmful effects of sugar-sweetened beverages on human health

Researchers at the Advanced Research Unit on Metabolism, Development & Aging (ARUMDA), in the Tata Institute of Fundamental Research (TIFR, Mumbai and TIFR Hyderabad), have unveiled a comprehensive understanding of the harmful effects of sugar-sweetened beverages (SSBs) on human health, using a preclinical mouse model that closely mimics human consumption patterns.

21 Mar 2025

Scientists uncover hints of a potential new cause of stomach cancer

For the first time, scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer.

19 Mar 2025

CB1R inhibition shows promise in protecting gut barrier from alcohol damage

Heavy alcohol consumption is a leading cause of gastrointestinal diseases, with binge drinking linked to increased intestinal permeability-a condition commonly known as "leaky gut."

19 Mar 2025

Small intestine grows in response to pregnancy in mice

Researchers at the Francis Crick Institute have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a second.

19 Mar 2025

Earliest stages and possible new cause of stomach cancer revealed

For the first time, scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer.

19 Mar 2025

Maternal high-fat diets linked to liver stress in unborn babies

When mothers eat a diet high in fat and sugars, their unborn babies can develop liver stress that continues into early life.

14 Mar 2025

How to pick healthier gluten-free bread

Gluten-free (GF) breads and flours often contain less natural fiber and more fat than gluten-containing counterparts, with added psyllium or gums boosting fiber at the cost of higher saturated fats. Researchers urge better formulation to match GF diets’ nutritional quality to traditional options.

9 Mar 2025

Study uncovers how glucose excreted in the gut converts into beneficial fatty acids

Gut microbes that were thought to feed exclusively on dietary fiber also get fed sugar from our guts, from which they produce short-chain fatty acids that are crucial to many body functions.

4 Mar 2025

Grapefruit juice and its effects on prescription drugs

Grapefruit juice can interfere with how certain medications work by affecting drug metabolism and absorption, leading to either increased side effects or reduced effectiveness. The FDA requires warnings on some drugs due to these interactions, making it essential to check labels and consult healthcare providers.

28 Feb 2025