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Stopping 'budding' viruses in their tracks

Paramyxoviruses have the potential to trigger a devastating pandemic. This family of viruses includes measles, Nipah virus, mumps, Newcastle disease and canine distemper.

20 Jul 2022

Chewing gum containing plant-based antiviral proteins neutralizes SARS-CoV-2 and influenza viruses

A new study has explored the entrapment efficacy of CTB-ACE2 chewing gum against different strains of SARS-CoV-2.

20 Jul 2022

COVID-19 vaccine-boosted neutralizing antibody levels decrease substantially within 3 months

Although COVID-19 booster vaccinations in adults elicit high levels of neutralizing antibodies against the Omicron variant of SARS-CoV-2, antibody levels decrease substantially within 3 months, according to new clinical trial data.

19 Jul 2022

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Researchers studied open and closed conformations of the C-terminal of SARS-CoV-2 nucleocapsid (N) protein termed the NCTD.

19 Jul 2022

Study provides detailed understanding of SARS-CoV-2 Omicron sublineage antibody escape

A new study reveals the antibody-mediated neutralization of both current and emerging Omicron subvariants.

13 Jul 2022

Study describes biochemical pathway that leads to inflammation characteristic of autoimmune diseases

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and well-being.

13 Jul 2022

Prion imaging could lead to better understanding of what causes fatal neurological disorders

Prion diseases are incurable, deadly neurological disorders that can affect both humans and animals–including Creutzfeldt-Jakob Disease (CJD) in people, Bovine Spongiform Encephalopathy (also known as Mad Cow Disease) and Chronic Wasting Disease found in deer.

13 Jul 2022

Study reveals a specific metabolic adaptation in some patients with acute myeloid leukemia

An article published in the journal Nature Communications describes a specific metabolic adaptation in some patients with acute myeloid leukemia affected by tandem mutations in the FLT3 gene.

13 Jul 2022

What are the biological features, prevention and control strategies against monkeypox?

Researchers elucidated the epidemiology and clinical presentation, biological features, pathogenicity and prevention and control strategies for monkeypox virus (MPXV) infections.

13 Jul 2022

Study suggests ZCB11 as a promising antibody drug against all SARS-CoV-2 variants of concern

Researchers at the AIDS Institute, The University of Hong Kong, Department of Microbiology, School of Clinical Medicine, the LKS Faculty of Medicine of The University of Hong Kong and the State Key Laboratory of Emerging Infectious Diseases, HKU, together with structural biologists at The Hong Kong University of Science and Technology, have demonstrated that ZCB11, a broadly neutralizing antibody derived from a local mRNA-vaccinee against the spreading Omicron variants of SARS-CoV-2, displays potent antiviral activities against all variants of concern (VOCs), including the dominantly spreading Omicron BA.1, BA1.1 and BA.2.

13 Jul 2022

The impact of the SARS-CoV-2 spike A222V mutation on viral infection

Researchers analyzed the structural function of the genetic background of SARS-CoV-2 in the appearance and persistence of A222V spike mutation.

13 Jul 2022

NIH launches clinical trial evaluating an experimental vaccine to prevent Nipah virus infection

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has launched an early-stage clinical trial evaluating an investigational vaccine to prevent infection with Nipah virus.

11 Jul 2022

UT Southwestern researchers reveal the physical mechanism behind a neurological autoimmune disease

Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers for the first time have captured images of an autoantibody bound to a nerve cell surface receptor, revealing the physical mechanism behind a neurological autoimmune disease.

11 Jul 2022

Researchers unravel the functioning of antibodies in autoimmune encephalitis

Using a state-of-the-art method, researchers at DZNE and the University of Texas have succeeded for the first time at unraveling the effects of autoimmune antibodies, that are directed against the brain, in detail at the atomic level.

8 Jul 2022

Knowledge of HIV Pol polyprotein's structure could spur the development of new therapies

In a discovery that could spur the development of new therapies for more than 40 million HIV patients worldwide, scientists from Rutgers University and the Salk Institute determined the molecular structure of the HIV Pol polyprotein, a protein that plays a critical role in helping the virus propagate itself and spread throughout the body.

7 Jul 2022

Chicoric acid a potential candidate for COVID-19 treatment

An article under review in the Scientific Reports journal and currently available on the Research Square* preprint server reports on chicoric acid (CA) as a potential inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Jul 2022

COVID-19 impairs the insulin/IGF signaling pathway

Scientists evaluate the impact of SARS-CoV-2 on the insulin/IGF signaling pathway.

6 Jul 2022

COVID-19 was third leading cause of death in the United States between March 2020 and October 2021

COVID-19 was the third leading cause of death in the United States between March 2020 and October 2021, according to an analysis of national death certificate data by researchers at the National Cancer Institute, part of the National Institutes of Health. The study appears July 5 in JAMA Internal Medicine.

5 Jul 2022

Novel oral nano-in-micro system provides efficient curcumin delivery to alleviate ulcerative colitis

A new study showed that the newly designed oral nano-in-micro hydrogel delivery platform could be efficiently used to deliver curcumin for the treatment of Ulcerative Colitis.

5 Jul 2022

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

In a new study, researchers reported on the non-ACE2 blocking neutralizing antibodies elicited in response to severe coronavirus disease 2019 using deep ribonucleic acid sequencing with >100 million reads per sample and molecular dynamic simulations.

5 Jul 2022

Electron News and Research

Stopping 'budding' viruses in their tracks

Chewing gum containing plant-based antiviral proteins neutralizes SARS-CoV-2 and influenza viruses

COVID-19 vaccine-boosted neutralizing antibody levels decrease substantially within 3 months

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Study provides detailed understanding of SARS-CoV-2 Omicron sublineage antibody escape

Study describes biochemical pathway that leads to inflammation characteristic of autoimmune diseases

Prion imaging could lead to better understanding of what causes fatal neurological disorders

Study reveals a specific metabolic adaptation in some patients with acute myeloid leukemia

What are the biological features, prevention and control strategies against monkeypox?

Study suggests ZCB11 as a promising antibody drug against all SARS-CoV-2 variants of concern

The impact of the SARS-CoV-2 spike A222V mutation on viral infection

NIH launches clinical trial evaluating an experimental vaccine to prevent Nipah virus infection

UT Southwestern researchers reveal the physical mechanism behind a neurological autoimmune disease

Researchers unravel the functioning of antibodies in autoimmune encephalitis

Knowledge of HIV Pol polyprotein's structure could spur the development of new therapies

Chicoric acid a potential candidate for COVID-19 treatment

COVID-19 impairs the insulin/IGF signaling pathway

COVID-19 was third leading cause of death in the United States between March 2020 and October 2021

Novel oral nano-in-micro system provides efficient curcumin delivery to alleviate ulcerative colitis

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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