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Toxic levels of Alzheimer's clusters in brain determined

Scientists have long suspected that Alzheimer's disease (AD) is caused by a small protein called the amyloid β-protein (Aβ). This protein clumps or binds to itself, eventually changing chemically to create brain protein deposits (plaques) that are characteristic of AD.

11 Aug 2009

New class of molecules capable of blocking formation of tau protein fibrils

A new class of molecules capable of blocking the formation of specific protein clumps that are believed to contribute to Alzheimer’s disease pathology has been discovered by researchers at the University of Pennsylvania School of Medicine. By assaying close to 300,000 compounds, they have identified drug-like inhibitors of AD tau protein clumping, as reported in the journal Biochemistry.

11 Aug 2009

Electrodiagnostic and neuromuscular medicine featured at AANEM annual meeting

The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) will hold its 56th annual meeting in San Diego, California, from October 7-10, 2009 at the Manchester Grand Hyatt.

10 Aug 2009

Vulvodynia, the most frequent cause of painful sex

PAINFUL SEX. It's a secret that millions of women live with in embarrassment and isolation. Until now. . .

10 Aug 2009

Transcranial MR-guided focused ultrasound for brain disorders a step closer

A team of researchers working at the MR-Center of the University Children's Hospital in Zürich has completed a pilot study using transcranial MR-guided focused ultrasound to treat 10 patients with neuropathic pain.

9 Aug 2009

Unlikely genetic suspect implicated in Dandy-Walker malformation

A genetic search that wound its way from patients to mouse models and back to patients has uncovered an unlikely gene critically involved in a common birth defect which causes mental retardation, motor delays and sometimes autism, providing a new mechanism and potentially improving treatment for the disorder.

9 Aug 2009

Compound from coral offers hope fpr neuropathic pain

A compound initially isolated from a soft coral (Capnella imbricata) collected at Green Island off Taiwan, could lead scientists to develop a new set of treatments for neuropathic pain - chronic pain that sometimes follows damage to the nervous system.

4 Aug 2009

Clinical trial to test gene therapy for Alzheimer’s disease

Researchers at the Shiley-Marcos Alzheimer's Disease Research Center at the University of California San Diego are about to launch a Phase 2 clinical trial to test a gene therapy treatment for Alzheimer’s disease (AD) called CERE-110.

4 Aug 2009

Regional nerve block anesthesia improve recovery, outcomes

When planning for surgery, patients too often don't consider the kind of anesthesia they will receive. In fact, the choice of anesthesia can improve recovery, even outcomes.

4 Aug 2009

Stem cell technology innovation could reduce the number of animal experiments

Researchers from the University of Bath are embarking on a project to use stem cell technology that could reduce the number of animal experiments used to study conditions such as motor neurone disease.

4 Aug 2009

Dysport, an anti-wrinkle alternative to Botox

The new anti-wrinkle facial filler Dysport, which could be used as an alternative to Botox, noticeably reduced frown lines between the eyes, according to users and independent reviewers in a study involving plastic surgeons at UT Southwestern Medical Center.

3 Aug 2009

Senate Democrats in the 'hot seat' on health overhaul

In the final week of debate before the Senate recess, the Finance Committee continues talks on bipartisan legislation, but both Republicans and Democrats are ramping up their health care rhetoric and considering more drastic options.

3 Aug 2009

Gene therapy for retinitis pigmentosa

An international team of scientists and clinicians from the United States and Saudi Arabia are working to develop gene therapy for treating a rare, hereditary retinal disease.

31 Jul 2009

Surgical treatment of migraine safe and effective

Migraine headaches are a drain - not only on the estimated 30 million Americans who suffer from them, but on the economy, too. Because pain and other symptoms caused by migraine headaches can be quite severe, it is projected that nearly $13 billion is spent every year in headache treatment and loss of time from work, which no one can afford these days.

31 Jul 2009

Enzyme implicated in blood flow in Alzheimer’s, disease progression

Researchers have discovered that the enzyme, endothelin converting enzyme-2 (ECE-2), may cause the decrease in blood flow in the brain seen in Alzheimer's disease and contribute to progression of the disease.

27 Jul 2009

Airway cells are chemosensory

The same mechanism that helps you detect bad-tasting and potentially poisonous foods may also play a role in protecting your airway from harmful substances, according to a study by scientists at the University of Iowa Roy J. and Lucille A. Carver College of Medicine.

24 Jul 2009

Help is on the way for shy, anxious drinkers

In life today alcohol plays an enormous part in many people's social activities and is often an essential part of a night out with friends.

20 Jul 2009

Potential new treatment for Alzheimer’s

Indeed, these carriers tend to develop the disease later than others, but when that happens, it progresses more rapidly and does not respond to medication. Therefore, the bottom line is that carriers of the mutated gene have a greater risk than others for disease progression.

20 Jul 2009

TGF beta blocker prevents epilepsy following traumatic brain injury

Dr. Alon Friedman, a neurosurgeon, professor and researcher at Ben-Gurion University of the Negev, working with researchers from UC Berkeley, California have identified a TGF Beta Blocker that when given to rats prevents epilepsy after brain damage, according to a new study appearing in the July 15 issue of the Journal of Neuroscience.

19 Jul 2009

Depression and stress worsen childhood asthma

Young people with asthma have nearly twice the incidence of depression compared to their peers without asthma, and studies have shown that depression is associated with increased asthma symptoms and, in some cases, death.

17 Jul 2009