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Study: Oats and rye brans reduce weight gain, hepatic inflammation

In a newly published experimental study, the consumption of dietary fibre from oat and rye brans supported the growth of beneficial gut microbiota, which in turn ameliorated cholesterol metabolism, enhanced gut barrier function and reduced hepatic inflammation.

2 Jul 2020

SARS-CoV-2 infection modeling in iPSC-derived type 2 cells

The most fatal form of COVID-19 disease is acute respiratory distress syndrome (ARDS), caused by direct viral injury as well as indirect noxious effects caused by cytotoxic chemicals and inflammatory processes. A new study published on the preprint server bioRxiv* in June 2020 shows that this is partly due to the rapid onset of inflammation caused by the infection of type 2 alveolar cells with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Jul 2020

Research reveals the molecular landscape of myelodysplastic/myeloproliferative neoplasms

Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) is a group of rare malignancies with overlapping features from myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN), that include a variety of diseases depending on their phenotype (hematological and morphological characteristics).

1 Jul 2020

Researchers discover a protein that protects B cells from stress-induced cell death

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, which produce antibodies that target and neutralize pathogens.

1 Jul 2020

CHOP researchers receive multi-million dollar grant to study disease risk in African Americans

The National Institutes of Health announced today that researchers from Children's Hospital of Philadelphia are among the recipients of a multi-million dollar grant that focuses on the use of genomics to improve risk assessment for diverse populations and integrate the findings into clinical care.

1 Jul 2020

Study sheds light on selective neuronal vulnerability in Alzheimer’s disease

When Alzheimer's disease strikes, the entire brain doesn't crumble at once. Instead the mind unravels like grim clockwork, beginning with the telltale degradation of a group of brain cells in the entorhinal cortex.

1 Jul 2020

Research reveals new genetic insights into how the brain folds

New research is helping unlock the mystery of how the brain folds as a baby develops in the womb - a process critical to healthy brain function.

1 Jul 2020

Air pollution may lead to interstitial lung diseases

More research must be done to investigate the role of air pollution on the epigenome in patients with interstitial lung diseases (ILDs), in order to develop strategies that minimize the effects of these pollutants, according to a new article published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

1 Jul 2020

Phosphorylation of SARS-CoV-2 N protein affects its function

Now, a new study by researchers at the University of California San Francisco and published on the preprint server bioRxiv* in June 2020 shows the effect of phosphorylation on the state and function of the N protein.

1 Jul 2020

New swine flu strain with pandemic potential found in China

As the world grapples with a novel coronavirus pandemic, a new strain of swine flu that can trigger a pandemic has been reported.

30 Jun 2020

Researchers uncover a potentially promising strategy to target brain tumors

Gliomas with mutations in what are called the isocitrate dehydrogenase (IDH) genes are the most common brain tumors diagnosed in younger adults aged 18 to 45 years.

30 Jun 2020

A data-rich atlas of the developing human brain

For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in a precise symphony.

30 Jun 2020

Genomic sequencing to provide precision medicine for aromatase deficiency

An international team of scientists from Switzerland Spain, has studied the genetic basis of aromatase deficiency, a rare metabolic disorder that prevents the production of estrogens in humans, according to new research in JCEM.

30 Jun 2020

Researchers identify new step in brain cell mechanism that shows promise for treating epilepsy

Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy.

30 Jun 2020

GHGA to address need for access to genomic and phenomic data

In Germany, there is currently a lack of infrastructure to deal with high-volume biological and biomedical data, such as data found in medical records.

30 Jun 2020

Glitches in DNA replication have important implications for treating cancer

USC researchers peering deep inside a living cell have discovered something surprising: Its system for preventing genetic damage linked to diseases can fail so badly that the cell would be better off without it.

30 Jun 2020

Spike protein and human ACE2 binding ability shows SARS-CoV-2 viral adaptation

A new study published on the preprint server bioRxiv in June 2020 reports some important findings that could shed light on this question. As the pandemic marches on, having claimed over 500,000 lives and caused well over 10 million infections to date, the task of defining and predicting factors that predispose to infectivity across species becomes ever more critical.

30 Jun 2020

Researchers search for SARS-CoV-2 fomites on an operational Italian bus

A new study reports the results of a viral detection study carried out in buses used for public transport across the final week of lockdown, as travel restrictions were being lifted step by step. This study by Italian researchers and published on the preprint server bioRxiv* in June 2020, may help to understand how a virus can spread within a city bus during normal operation and how effective are the measures used to protect against such transmission.

30 Jun 2020

Identification of SARS-CoV-2 RNA in healthcare HVAC units

Now, a new study published on the preprint server medRxiv* in June 2020 reports that viral RNA has been found to occur in HVAC (Heating, Ventilation, and AC) units in healthcare facilities. However, it is not clear if this represents a possible mechanism of viral transmission.

30 Jun 2020

Breast milk even more beneficial for baby if mother exercises regularly, finds study

A new study from the Ohio State University Wexner Medical Centre shows that if breastfeeding mothers exercise regularly, they may end up providing more beneficial breast milk. Exercise is known to benefit individuals in various ways, and this new study shows that there are probably more advantages to exercising than previously known.

29 Jun 2020