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IU researchers aim to develop a new therapy for glaucoma

Researchers at Indiana University School of Medicine are using a novel approach to hopefully develop a new therapy for glaucoma, a complex disease that eventually leads to blindness, thanks to a new five-year, $2 million R01 grant from the National Eye Institute.

8 Jan 2024

Combining immunotherapy and radiation to tackle aggressive triple-negative breast cancer

Cedars-Sinai Cancer investigators have analyzed the cells within triple-negative breast cancer tumors before and after radiation therapy with immunotherapy, identifying three patient groups with different responses to the treatment.

8 Jan 2024

UCSF research lays the groundwork for preventing deafness

Researchers have found a gene that links deafness to cell death in the inner ear in humans – creating new opportunities for averting hearing loss.

8 Jan 2024

Bacterial "freight elevator" unpacked: How pathogens hide from the immune system

Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane.

8 Jan 2024

Engineered virus-like particles power up gene editing, correcting blindness in mice

Prime editing, a versatile form of gene editing that can correct most known disease-causing genetic mutations, now has a new vehicle to deliver its machinery into cells in living animals.

8 Jan 2024

Growing tiny tumors in the lab for personalized lung cancer treatment

Lung cancer accounts for nearly 20% of annual cancer-related deaths worldwide. According to 2022 statistics from the Swiss Cancer League, nearly 5,000 new cases of lung cancer are reported in Switzerland each year.

8 Jan 2024

AI reveals hidden rules of cell neighborhoods in cancer

Researchers from Children's Hospital of Philadelphia have developed a new AI-powered algorithm to help understand how different cells organize themselves into particular tissues and communicate with one another.

8 Jan 2024

Rising out-of-pocket costs for PrEP threaten key strategy in ending the HIV epidemic

Increasing patients' out of pocket costs for HIV pre-exposure prophylaxis (PrEP), medications, which have been shown to dramatically reduce the risk of HIV infection, could lead to a significant reduction in PrEP use and a rise in HIV infection rates, according to a new study co-led by researchers at the Perelman School of Medicine at the University of Pennsylvania and Johns Hopkins Bloomberg School of Public Health.

8 Jan 2024

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

The current evidence of the role of gut microbiota in Alzheimer’s disease (AD) pathogenesis.

8 Jan 2024

Genetic keys to COVID-19 vaccine response unlocked

A genome-wide association study in the U.K. Biobank reveals genetic factors influencing IgG serostatus against SARS-CoV-2, highlighting the role of HLA class II genes in variable immune responses to COVID-19 vaccines.

7 Jan 2024

Sesame protein-derived peptides show promise in fighting E. coli and S. aureus

A study in "Nutrients" reveals that sesame protein-derived peptides, Ala-Gly-Gly-Val-Pro-Arg and Ser-Thr-Ile-Arg, show effective antibacterial activity against Escherichia coli and Staphylococcus aureus.

7 Jan 2024

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment.

5 Jan 2024

Fruit fly research solves human disease and fuels new cancer immunotherapy approach

Scientists have solved a cellular murder mystery nearly 25 years after the case went cold. Following a trail of evidence from fruit flies to mice to humans revealed that cannibalistic cells likely cause a rare human immunodeficiency.

5 Jan 2024

Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code.

5 Jan 2024

St. Jude scientists develop novel spectinomycin derivatives to combat Mycobacterium abscessus

Scientists at St. Jude Children's Research Hospital are tackling Mycobacterium abscessus (Mab) antibiotic resistance.

5 Jan 2024

Study reveals novel mechanism driving hypertension-induced arterial disease

A new study in Advanced Science unlocks the secrets of how high blood pressure (hypertension) fuels the progression of arterial disease.

5 Jan 2024

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Compounds that obstruct the "landing gear" of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19, a study published today and led by Dana-Farber Cancer Institute scientists shows.

5 Jan 2024

IKAROS: Unlocking the secrets of the immune system's key player

In a scientific breakthrough that aids our understanding of the internal wiring of immune cells, researchers at Monash University in Australia have cracked the code behind IKAROS, an essential protein for immune cell development and protection against pathogens and cancer.

5 Jan 2024

Uncovering the true culprit behind nanofiber-induced lung disease

The pathogenic potential of inhaling the inert fibrous nanomaterials used in thermal insulation (such as asbestos or fiberglass) is actually connected not to their chemical composition, but instead to their geometrical characteristics and size.

5 Jan 2024

Study identifies 9 novel genes linked to gestational diabetes

The largest genetic study of gestational diabetes to date has led to a discovery of nine novel genetic regions linked to this severe and common pregnancy complication.

5 Jan 2024

Cell News and Research

IU researchers aim to develop a new therapy for glaucoma

Combining immunotherapy and radiation to tackle aggressive triple-negative breast cancer

UCSF research lays the groundwork for preventing deafness

Bacterial "freight elevator" unpacked: How pathogens hide from the immune system

Engineered virus-like particles power up gene editing, correcting blindness in mice

Growing tiny tumors in the lab for personalized lung cancer treatment

AI reveals hidden rules of cell neighborhoods in cancer

Rising out-of-pocket costs for PrEP threaten key strategy in ending the HIV epidemic

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

Genetic keys to COVID-19 vaccine response unlocked

Sesame protein-derived peptides show promise in fighting E. coli and S. aureus

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Fruit fly research solves human disease and fuels new cancer immunotherapy approach

Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

St. Jude scientists develop novel spectinomycin derivatives to combat Mycobacterium abscessus

Study reveals novel mechanism driving hypertension-induced arterial disease

Stapled lipopeptides show promise as broad-spectrum antiviral agents

IKAROS: Unlocking the secrets of the immune system's key player

Uncovering the true culprit behind nanofiber-induced lung disease

Study identifies 9 novel genes linked to gestational diabetes

Improve fermentation and cell culture performance with real-time gas analysis eBook

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