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Researchers identify a neural pathway critical to correcting behavioral errors

Mount Sinai researchers have identified a neural pathway through which the brain detects errors and guides subsequent behavioral improvement. This process, called cognitive control, is frequently dysregulated in a wide range of psychiatric disorders.

22 Feb 2021

Researchers create high throughput arrays of miniaturized 3D tumor models

By engineering common filter papers, similar to coffee filters, a team of NYU Abu Dhabi researchers have created high throughput arrays of miniaturized 3D tumor models to replicate key aspects of tumor physiology, which are absent in traditional drug testing platforms.

22 Feb 2021

WVU researchers set to identify SARS-CoV-2 variants, mitigate strain outbreaks

West Virginia University scientists knew it was coming. When health officials confirmed the first three cases of a COVID-19 variant in West Virginia late Friday (Feb. 19), they were not surprised.

22 Feb 2021

Kessler team receives funding to study factors leading to osteoarthritis after knee injury

Gerard Malanga, MD, and Nathan Hogaboom, PhD, of Kessler Foundation received a $185,707 award from The Geneva Foundation (Geneva) to study factors contributing to the development of osteoarthritis following acute knee injuries, a common disabling condition among active-duty military personnel.

22 Feb 2021

Current monoclonal antibodies less potent against SARS-CoV-2 variants

Researchers at the New York University Grossman School of Medicine and Biohaven Pharmaceuticals found that the REGN10933 and REGN10987 combination was 9.1-fold less potent on the B.1.351 variant, which emerged in South Africa, and 16.2-fold less potent on mink cluster 5.

22 Feb 2021

FDA-approved heart drug shows potential for treatment of SARS-CoV-2

A federally approved heart medication shows significant effectiveness in interfering with SARS-CoV-2 entry into the human cell host, according to a new study by a research team from Texas A&M University and The University of Texas Medical Branch.

22 Feb 2021

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

People living with the human immunodeficiency virus (HIV) who have a history of severe immunosuppression and at least one copy of the Alzheimer's disease-related gene variant APOE4, might see a compounded adverse effect on the circuitry that impacts memory.

22 Feb 2021

Novel vectors reduce the risks associated with ocular gene therapies

Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development.

22 Feb 2021

Scientists use patients' own stem cells to restore function after spinal cord injury

Intravenous injection of bone marrow derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report Feb. 18 in the Journal of Clinical Neurology and Neurosurgery.

22 Feb 2021

FDA issues guidance for medical product developers to address the emergence of SARS-CoV-2 variants

Today, the U.S. Food and Drug Administration issued guidances for medical product developers, specifically covering vaccines, diagnostics and therapeutics products, to address the emergence and potential future emergence of variants of SARS-CoV-2, the virus that causes COVID-19.

22 Feb 2021

New partnership launches Down syndrome research biobank

Cincinnati Children's Hospital Medical Center has collaborated with DownSyndrome Achieves (DSA) to launch a research biobank, which serves as a central repository for biospecimens donated by individuals with Down syndrome and their immediate families.

22 Feb 2021

Human monoclonal antibodies can act as a substitute for traditional antibiotics

In the course of a new and groundbreaking study, led by Dr, Natalia Freund and the doctoral candidate Avia Waston at the Sackler Medical Faculty, the research group succeeded in isolating monoclonal antibodies, which hindered the growth of tuberculosis germs in laboratory mice. The

22 Feb 2021

Xenograft model for invasive lobular carcinoma simulates tumor with high accuracy

Invasive lobular carcinoma (ILC) is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast.

22 Feb 2021

Study provides new information about the structure of prion proteins

Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals: Bovine Spongiform Encephalopathy (BSE) or 'mad cow' disease is one of the most famous since in 1996 scientists found that the agent responsible for the disease in cows, is the same agent responsible for the so-called variant Creutzfeldt-Jakob Disease (vCJD), a disease affecting humans.

20 Feb 2021

Study: Longevity gene protects brain stem cells from the harmful effects of stress

A gene linked to unusually long lifespans in humans protects brain stem cells from the harmful effects of stress, according to a new study by Weill Cornell Medicine investigators.

20 Feb 2021

Transforming immune killer T-cells into 'super soldiers' to fight against cancer

Creating "super soldiers" of specific white blood cells to boost an anti-tumour response has been shown in a series of elegant experiments by Princess Margaret researchers.

20 Feb 2021

Researchers seek to develop new cell culture technique to replace animal testing

While many studies take place in a petri glass in toxicology research, for some processes there is still a need for animal components such as serum or liver cell tissue.

20 Feb 2021

Chicken-derived antibody shows potent neutralizing capacity against SARS-CoV-2 in vitro

Researchers report on a Chicken-derived antibody against SARS-CoV-2, offering preliminary data on a potential therapeutic for COVID-19 warranting further research.

19 Feb 2021

Hydrogel injection could help repair damage to the heart muscle after heart attack

Researchers at CÚRAM, the SFI Research Centre for Medical Devices based at NUI Galway, and BIOFORGE Lab, at the University of Valladolid in Spain, have developed an injectable hydrogel that could help repair and prevent further damage to the heart muscle after a heart attack event.

19 Feb 2021

Developing Biochemically Sensitive Membranes with Electrochemistry

In this interview, News-Medical Life Sciences talks to Lane Baker, Professor of Chemistry at Indiana University Bloomington about the role of electrochemistry in developing biochemically sensitive membranes as well the work ongoing at the Baker lab.

From Pittcon 19 Feb 2021

Laboratory News and Research

Researchers identify a neural pathway critical to correcting behavioral errors

Researchers create high throughput arrays of miniaturized 3D tumor models

WVU researchers set to identify SARS-CoV-2 variants, mitigate strain outbreaks

Kessler team receives funding to study factors leading to osteoarthritis after knee injury

Current monoclonal antibodies less potent against SARS-CoV-2 variants

FDA-approved heart drug shows potential for treatment of SARS-CoV-2

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

Novel vectors reduce the risks associated with ocular gene therapies

Scientists use patients' own stem cells to restore function after spinal cord injury

FDA issues guidance for medical product developers to address the emergence of SARS-CoV-2 variants

New partnership launches Down syndrome research biobank

Human monoclonal antibodies can act as a substitute for traditional antibiotics

Xenograft model for invasive lobular carcinoma simulates tumor with high accuracy

Study provides new information about the structure of prion proteins

Study: Longevity gene protects brain stem cells from the harmful effects of stress

Transforming immune killer T-cells into 'super soldiers' to fight against cancer

Researchers seek to develop new cell culture technique to replace animal testing

Chicken-derived antibody shows potent neutralizing capacity against SARS-CoV-2 in vitro

Hydrogel injection could help repair damage to the heart muscle after heart attack

Developing Biochemically Sensitive Membranes with Electrochemistry

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