Vascular News and Research

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Russian team tests new polymeric coating for vascular stents

A group of researchers of the Institute of Biophysics (Russian Academy of Sciences), Krasnoyarsk regional clinical hospital and Krasnoyarsk regional department of morbid anatomy under the guidance of .I. Gitelzon, Academician of Russian Academy of Sciences, have tested characteristics of a new polymeric coating for vascular stents.

22 May 2005

Tumor vasculature has become an attractive target in the treatment of cancer.

Treatment with a protein fused to an antibody in tumor-bearing mice led to coagulation of the blood within the tumor blood vessels, tumor tissue death, and tumor growth delay, according to a new study in the May 18 issue of the Journal of the National Cancer Institute.

17 May 2005

Routinely reformatting computed tomography (CT) scans to view organs from several different directions may help radiologists improve diagnosis

"You can see things in one view that you might miss in another," said Craig Barnes, M.D., section head of pediatric radiology at Wake Forest Baptist's Brenner Children's Hospital. "It costs no more as relates to scan time or radiation exposure, and we believe it provides added value in diagnosis."

17 May 2005

Engineers have found a way to modify a plastic to anchor molecules that promote nerve regeneration, blood vessel growth or other biological processes

In the study led by Dr. Christine Schmidt, the researchers identified a piece of protein from among a billion candidates that could perform the unusual feat of attaching to polypyrrole, a synthetic polymer (plastic) that conducts electricity and has shown promise in biomedical applications.

17 May 2005

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

A unique, targeted anti-cancer drug appears to show promise against neuroendocrine tumors-stubborn cancers that have traditionally responded poorly to chemotherapy, according to research findings announced at the 2005 Annual Meeting of the American Society of Clinical Oncology (ASCO).

17 May 2005

Antibody combined with cancer drug shows promise against breast tumors

An antibody that targets the blood vessels nourishing tumors significantly reduced breast cancer formation and growth in mice when combined with a current cancer drug, according to researchers at UT Southwestern Medical Center.

16 May 2005

Bevacizumab (Avastin) combined with low-dose chemotherapy slows ovarian cancer

A targeted cancer drug given with low-dose chemotherapy shrank ovarian tumors and slowed progression of ovarian cancer in patients with recurrent disease, according to research findings presented by Agustin Garcia, M.D., principal investigator of the study and Director of Breast Cancer Research at the Women's Cancer Research Institute at the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center.

16 May 2005

Physical fitness and regular exercise reduces a major predictor of cardiovascular disease

Physical fitness and regular exercise reduces a major predictor of cardiovascular disease in adults with normal blood pressure or mild hypertension. Physical conditioning in the absence of medication is not, however, as advantageous to the more severe hypertensive patient, reported researchers at the American Society of Hypertension Twentieth Annual Scientific Meeting.

16 May 2005

Experts redefine hypertension

Leading US hypertension experts unveiled a new definition of hypertension at the American Society of Hypertension Inc. (ASH) Twentieth Annual Scientific Meeting.

16 May 2005

Erectile dysfunction, high blood pressure linked

Men with high blood pressure have a new reason to get their condition under control – they may be at risk for erectile dysfunction, medical experts announced at the American Society of Hypertension’s Twentieth Annual Scientific Meeting.

16 May 2005

Bevacizumab plus chemo extends survival beyond one year for large group of advanced lung cancer patients

Patients with a particular type of advanced lung cancer may have a new option based on data presented at the 2005 annual meeting of the American Society of Clinical Oncology showing that combining a drug that cuts off the cancer's blood supply with standard chemotherapy can shrink tumors and extend life.

15 May 2005

New anticancer drug SU11248 shows continued response for patients with late-stage kidney cancer

Recent studies of a new anticancer drug show continued response for patients with late-stage kidney cancer. Robert Motzer, MD, attending physician at Memorial Sloan-Kettering Cancer Center (MSKCC), reported a response rate of 40 percent in patients with metastatic (advanced) renal cell (kidney) cancer who received SU11248 in second-line therapy.

15 May 2005

Statin therapy is cost-effective for a wider range of individuals with vascular disease or diabetes than previously recognised

Current guidelines generally recommend the initiation of statin therapy when the estimated 10-year risk of a non-fatal heart attack or coronary death is at least 15-20%.

12 May 2005

MicroVention awarded key patent for Smart Hydrogel

MicroVention announced today that the U.S. Patent and Trademark Office has awarded the company U.S. Patent No. 6,878,384 for its proprietary environmentally-responsive or "smart" hydrogel called Intelligel.

11 May 2005

Jefferson vascular surgeons go on web to demonstrate less invasive treatment than vein stripping for varicose veins

Stripping is a lengthy procedure often performed under general anesthesia and requires a surgeon to make incisions in the groin and below the knee and remove the vein with a long, surgical instrument extending inside the leg to the knee.

10 May 2005

Research offers new molecular approaches to therapies for the most deadly cancers

Researchers at Wake Forest University Baptist Medical Center have found promising new molecular targets and treatment approaches for some of the most malignant brain tumors.

10 May 2005

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

The first study identified a protein that seems to control the malignant features of brain tumor cells, suggesting a new treatment target for anti-cancer drugs. Researchers found that a little-known protein called Fra-1 was effective in controlling vascular endothelial growth factor D, a factor that promotes the growth of new blood vessels in most malignant brain tumors.

8 May 2005

Nutritious cranberries good for the heart as well

Researchers say that cranberries improve the health of pigs’ hearts and may do the same for humans.

8 May 2005

Cranberries good for the heart

Compounds that occur naturally in cranberries may be good for the heart, researchers at the University of Wisconsin-Madison have found.

5 May 2005

Specific variants of genes predict bleeding after heart surgery

Duke University Medical Center researchers have found that the presence of specific variants of genes that control clotting and the contractility, or "tone," of blood vessels can double the ability of physicians to predict those heart surgery patients at greatest risk of bleeding after surgery.

4 May 2005

Vascular News and Research

Russian team tests new polymeric coating for vascular stents

Tumor vasculature has become an attractive target in the treatment of cancer.

Routinely reformatting computed tomography (CT) scans to view organs from several different directions may help radiologists improve diagnosis

Engineers have found a way to modify a plastic to anchor molecules that promote nerve regeneration, blood vessel growth or other biological processes

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

Antibody combined with cancer drug shows promise against breast tumors

Bevacizumab (Avastin) combined with low-dose chemotherapy slows ovarian cancer

Physical fitness and regular exercise reduces a major predictor of cardiovascular disease

Experts redefine hypertension

Erectile dysfunction, high blood pressure linked

Bevacizumab plus chemo extends survival beyond one year for large group of advanced lung cancer patients

New anticancer drug SU11248 shows continued response for patients with late-stage kidney cancer

Statin therapy is cost-effective for a wider range of individuals with vascular disease or diabetes than previously recognised

MicroVention awarded key patent for Smart Hydrogel

Jefferson vascular surgeons go on web to demonstrate less invasive treatment than vein stripping for varicose veins

Research offers new molecular approaches to therapies for the most deadly cancers

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

Nutritious cranberries good for the heart as well

Cranberries good for the heart

Specific variants of genes predict bleeding after heart surgery

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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