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Scientist wins 2021 Pioneer in Basic Science Award for breakthrough research on the inner ear

When Andrew Griffith, MD, PhD, looks at the inner ear, he sees what he describes as "an engineering marvel."

28 Jan 2021

Viral ExoN regulates the rate of recombination in SARS-CoV-2

Researchers at Vanderbilt University Medical Center (VUMC) and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles' heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics.

28 Jan 2021

SMART protocol improves cognitive function, psychological well-being in laboratory participants

Many people believe that they can't change their brains, or that their brain health will inevitably decline as they age.

28 Jan 2021

Innovative breakthrough promises to diagnose DNA rearrangement mutations

Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities.

28 Jan 2021

American scientists receive the 2021 Paul Ehrlich and Ludwig Darmstaedter Prize

FRANKFURT am MAIN. Two American scientists, Bonnie L. Bassler and Michael R. Silverman, receive the 2021 Paul Ehrlich and Ludwig Darmstaedter Prize, which is endowed with 120,000 €.

28 Jan 2021

Genetically engineered cartilage delivers anti-inflammatory drug in response to knee activity

Working to develop new treatments for osteoarthritis, researchers at Washington University School of Medicine in St. Louis have genetically engineered cartilage to deliver an anti-inflammatory drug in response to activity similar to the bending of a knee or other motions that put stress on joints.

27 Jan 2021

New automated measurement system to assess healthy lifespans using nematodes

A research group from Kumamoto University (Japan) has developed an automated measurement system to assess healthy lifespans using nematodes (C. elegans).

27 Jan 2021

Study shows how aneuploidy could become a weak point for cancer cells

What makes cancer cells different from ordinary cells in our bodies? Can these differences be used to strike at them and paralyze their activity? This basic question has bothered cancer researchers since the mid-19th century.

27 Jan 2021

Allarity Therapeutics announces plans to test antiviral activity of stenoparib drug

Allarity Therapeutics of Hørsholm, Denmark, today announced plans to further test the antiviral activity of stenoparib, its PARP inhibitor, against SARS-CoV-2 lineage B.1.1.7, also known as Coronavirus Variant B117 (the "British variant"), at the COVID-19 Testing Service Center (CTSC) of Northern Arizona University's Pathogen and Microbiome Institute (PMI), a leading U.S. infectious disease testing center.

27 Jan 2021

New ACR Steering Committee established to guide diagnostic testing during COVID-19 pandemic

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today announced the formation of the AMP COVID Response (ACR) Steering Committee to help coordinate and communicate the organization's continued efforts to guide diagnostic testing during the ongoing COVID-19 pandemic and preparations for future emerging outbreaks.

27 Jan 2021

Wistar researchers discover new enzymatic function of the Epstein-Barr Virus protein

Researchers at The Wistar Institute have discovered a new enzymatic function of the Epstein-Barr Virus (EBV) protein EBNA1, a critical factor in EBV's ability to transform human cells and cause cancer.

27 Jan 2021

Two-drug combination approach could be effective against bone cancer

An innovative approach to treating bone tumors - starving cancer cells of the energy they need to grow - could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests a new study from Washington University School of Medicine in St. Louis.

27 Jan 2021

Cell phone data can reveal behavioral changes in people diagnosed with flu-like illness

Cell phone data that is routinely collected by telecommunications providers can reveal changes of behavior in people who are diagnosed with a flu-like illness, while also protecting their anonymity, a new study finds.

26 Jan 2021

Iron-carrying extracellular vesicles promote viral-bacterial co-infection

The mechanism by which acute viral respiratory infections promote secondary bacterial growth and infection in the airways depends on iron-carrying extracellular sacs secreted by the cells lining the host's airways, report researchers from the University of Pittsburgh School of Medicine in a paper published today in Cell Reports.

26 Jan 2021

Two enzymes fuel transition from pre-cancer stem cells to leukemia stem cells

Since stem cells can continually self-regenerate, making more stem cells, and differentiate into many different specialized cell types, they play an important role in our development and health.

26 Jan 2021

Sodium fluorescein may improve the safety and outcomes of vestibular schwannoma surgery

Removing a vestibular schwannoma - a slow-growing, benign tumor that develops in the nerves connecting the inner ear to the brain - is a delicate procedure. Surgeons must differentiate the tumor from nearby nerves, arteries, and other intracranial structures.

26 Jan 2021

Genetic interactions may shed light on NGLY1 deficiency

In 2012, four-year-old Bertrand Might became the first-ever patient diagnosed with a rare genetic disorder called N-glycanase (NGLY1) deficiency. The discovery of this condition and Bertrand's diagnosis allowed doctors to look for other children with the same genetic defect. Since then, more than 60 additional patients have been found.

26 Jan 2021

Microwaves used to inactivate aerosolized pathogens

As the pandemic has continued to spread globally, studies indicate the COVID-19 virus may be contained in aerosols that can be generated and spread through breathing, coughing, sneezing, or talking by infected individuals.

26 Jan 2021

New recommendations to improve apps for controlling and monitoring NTDs

A study performed by the Universitat Oberta de Catalunya provided eight recommendations for improving the online technology to help with the treatment and diagnosis of neglected tropical diseases (NTDs).

26 Jan 2021

SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation

Researchers at the Erasmus Medical Centre in the Netherlands and the University of Illinois at Urbana-Champaign in the US found that SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation and that this can be prevented by using cell lines with an active serine protease-mediated entry pathway.

26 Jan 2021

Laboratory News and Research

Scientist wins 2021 Pioneer in Basic Science Award for breakthrough research on the inner ear

Viral ExoN regulates the rate of recombination in SARS-CoV-2

SMART protocol improves cognitive function, psychological well-being in laboratory participants

Innovative breakthrough promises to diagnose DNA rearrangement mutations

American scientists receive the 2021 Paul Ehrlich and Ludwig Darmstaedter Prize

Genetically engineered cartilage delivers anti-inflammatory drug in response to knee activity

New automated measurement system to assess healthy lifespans using nematodes

Study shows how aneuploidy could become a weak point for cancer cells

Allarity Therapeutics announces plans to test antiviral activity of stenoparib drug

New ACR Steering Committee established to guide diagnostic testing during COVID-19 pandemic

Wistar researchers discover new enzymatic function of the Epstein-Barr Virus protein

Two-drug combination approach could be effective against bone cancer

Cell phone data can reveal behavioral changes in people diagnosed with flu-like illness

Iron-carrying extracellular vesicles promote viral-bacterial co-infection

Two enzymes fuel transition from pre-cancer stem cells to leukemia stem cells

Sodium fluorescein may improve the safety and outcomes of vestibular schwannoma surgery

Genetic interactions may shed light on NGLY1 deficiency

Microwaves used to inactivate aerosolized pathogens

New recommendations to improve apps for controlling and monitoring NTDs

SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation

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