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New analysis finds persistent racial, ethnic disparities in survival rates for early-onset colon cancer

Five-year survival for younger adults with colorectal cancer (CRC) improved only for Whites between 1992 and 2013, according to a new analysis to be presented at Digestive Disease Week 2022.

24 May 2022

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute have identified a new molecular drug target that could result in new cancer drugs with fewer side effects.

20 May 2022

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Investigators from Rutgers Cancer Institute of New Jersey, New Jersey's only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.

19 May 2022

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Imugene Limited, a clinical stage immuno-oncology company, and City of Hope, one of the largest cancer research and treatment organizations in the United States, today announced that the first patient was dosed in a Phase 1 clinical trial evaluating the safety of novel cancer-killing virus CF33-hNIS VAXINIA when used in people with advanced solid tumors.

18 May 2022

Why do diabetic patients have more severe SARS-CoV-2 infections?

A recent study published in the journal Cell Metabolism illustrated the function of angiotensin-converting enzyme 2 (ACE2) in renal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among diabetic patients.

16 May 2022

Researchers discover new gene that confers resistance to prostate cancer treatment

Northwestern Medicine investigators have identified a gene that confers resistance to a common prostate cancer treatment, according to a study published in Cancer Research.

13 May 2022

Tumors release lactate to force neighboring cells into supporting cancer growth

Tumors can force neighboring cells into supporting cancer growth by releasing lactate into their local environment, according to researchers at Weill Cornell Medicine.

10 May 2022

Study identifies interleukin-6 as a potential target in refining cancer therapies

Immune checkpoint inhibitors have revolutionized the treatment of many cancers by using our body's immune system to kill cancer.

9 May 2022

Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

It's not often that a failed clinical trial leads to a scientific breakthrough. When patients in the UK started showing adverse side effects during a cancer immunotherapy trial, researchers at La Jolla Institute for Immunology (LJI) Center for Cancer Immunotherapy and University of Liverpool went back through the data and worked with patient samples to see what went wrong.

5 May 2022

Study investigates stress granule formation during infection with the human common cold coronavirus and SARS-CoV-2

Researchers analyzed the inhibition of stress granules formation in cells infected by the human common cold coronavirus HCOV-OC43 and SARS-CoV-2.

5 May 2022

Research suggests Twitter as a powerful tool to drive awareness about pancreatic cancer

A new study investigating pancreatic cancer-related Twitter conversations has found high rates of engagement among patients, advocates, and non-healthcare related individuals active in the pancreatic cancer space.

5 May 2022

Hydrogen sulfide production in the gut is based on animal- or plant-based diet, study finds

Published in Clinical Nutrition, researchers from the University of Minnesota Medical School looked at colonic hydrogen sulfide - a toxic gas in the body that smells like rotten eggs - production in people in response to animal- and plant-based diet interventions.

4 May 2022

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Researchers reviewed the potential clinically relevant mechanisms by which microbiota and microbiota-derived metabolites influence the host immune responses to SARS-CoV-2 infection.

3 May 2022

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

A new study published in the journal Gastroenterology used upper and lower gastrointestinal endoscopy to assess whether gut antigen persistence leads to post-acute COVID-19 in patients with or without post-acute COVID-19 symptoms.

3 May 2022

Combining two cancer drugs can be effective in treating specific type of colorectal cancer, study shows

Researchers at the Case Western Reserve University School Medicine have found that combining two cancer drugs can be effective in treating a specific type of colorectal cancer, according to a new study published in Nature Communications.

2 May 2022

Improving Medical Communication through Social Media

News-Medical interviews Dr. Benjamin Schmidt about using social media to highlight different perspectives in the medical community and improve communication between patients and doctors.

29 Apr 2022

Study investigates intestinal ischemia in COVID-19 patients

A team of Italian scientists has presented case reports of five coronavirus disease 2019 (COVID-19) patients undergoing emergency surgery for intestinal ischemia.

28 Apr 2022

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

A plant virus that infects legumes, called cowpea mosaic virus, has a special power that you may not have known about: when injected into a tumor, it triggers the immune system to treat the cancer - even metastatic cancer - and prevents it from recurring.

27 Apr 2022

Researchers use a systems biology approach to parse the genetic diversity of C. difficile

Researchers at University of California San Diego School of Medicine and Jacobs School of Engineering, with colleagues at Baylor College of Medicine, have used a systems biology approach to parse the genetic diversity of Clostridioides difficile, a particularly problematic pathogen in health care settings.

27 Apr 2022

“Keto” molecule could someday become a part of colorectal cancer care and prevention

A molecule produced in the liver in response to low-carb "ketogenic" diets has a powerful effect in suppressing colorectal tumor growth and may be useful as a preventive and treatment of such cancers, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

27 Apr 2022

Colon News and Research

New analysis finds persistent racial, ethnic disparities in survival rates for early-onset colon cancer

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Why do diabetic patients have more severe SARS-CoV-2 infections?

Researchers discover new gene that confers resistance to prostate cancer treatment

Tumors release lactate to force neighboring cells into supporting cancer growth

Study identifies interleukin-6 as a potential target in refining cancer therapies

Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

Study investigates stress granule formation during infection with the human common cold coronavirus and SARS-CoV-2

Research suggests Twitter as a powerful tool to drive awareness about pancreatic cancer

Hydrogen sulfide production in the gut is based on animal- or plant-based diet, study finds

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

Combining two cancer drugs can be effective in treating specific type of colorectal cancer, study shows

Improving Medical Communication through Social Media

Study investigates intestinal ischemia in COVID-19 patients

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

Researchers use a systems biology approach to parse the genetic diversity of C. difficile

“Keto” molecule could someday become a part of colorectal cancer care and prevention

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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