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Researchers identify a new risk factor for multiple neurodegenerative diseases

Scientists at the HudsonAlpha Institute for Biotechnology, the University of California, San Francisco (UCSF), and the University of Alabama at Birmingham (UAB), have identified a new risk factor for multiple neurodegenerative diseases.

28 Apr 2020

Antibiotic exposure and its priming effect on disease-causing bacteria

Antibiotics save lives -- but using them also helps antibiotic-resistant strains evolve and spread. Each year, antibiotic-resistant bacteria infect some 2.8 million people in the United States, killing more than 35,000, according to the Centers for Disease Control and Prevention.

27 Apr 2020

Researchers develop new method for remotely stimulating activity in deep brain regions

University of Texas at Dallas researchers have developed a promising method for remotely stimulating activity in deep brain regions, advancing understanding of how molecules act in the brain and paving the way for better cancer treatments and therapies for other diseases.

27 Apr 2020

Prolonged corticosteroid treatment increases adrenal gland inflammation

New research by academics at the University of Bristol has found evidence that prolonged treatment of synthetic corticosteroid drugs increases adrenal gland inflammation in response to bacterial infection, an effect that in the long-term can damage adrenal function.

27 Apr 2020

SARS-CoV-2 readily infects human intestinal cells in a laboratory model

A new Dutch study available on bioRxiv uses differentiated human small intestinal organoids in vitro to demonstrate that intestinal epithelium supports the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and elicits a strong generic immune response.

27 Apr 2020

Scientists decode herpes simplex virus 1

Until now, scientists had assumed that there are about 80 so-called open reading frames (ORFs) in the genome of herpes simplex virus 1 (HSV-1).

27 Apr 2020

Investigational drug may hold benefit for patients with lung and ovarian cancers

In a first-time disclosure of IPN60090, a small-molecule inhibitor of the metabolic enzyme glutaminase (GLS1), researchers from The University of Texas MD Anderson Cancer Center's Therapeutics Discovery division and Ipsen Biopharmaceuticals reported the preclinical discovery and early-stage clinical development of this novel drug. IPN60090, now under investigation in a Phase I trial, may hold benefit for certain patients with lung and ovarian cancers.

27 Apr 2020

Talazoparib did not show overall survival benefit in patients with advanced BRCA-mutated breast cancer

New data from the Phase III EMBRACA trial led by researchers at The University of Texas MD Anderson Cancer Center found the PARP inhibitor talazoparib did not demonstrate a statistically significant overall survival (OS) benefit for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes.

27 Apr 2020

Rice University looks to ‘trap and zap’ SARS-CoV-2 in wastewater

A team of researchers from Rice University has won a National Science Foundation (NSF) RAPID grant to adapt their wastewater nanotechnology project to help trap and inactivate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), (which causes COVID-19 disease), in wastewater. This could help public health officials deal with the threat of disease transmission through wastewater.

27 Apr 2020

FAU scientists aim to develop a passive vaccine against COVID-19

Nothing less than the development of a passive vaccine against Covid-19 has been undertaken by a team of scientists from Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsklinkum Erlangen and their partners from the Fraunhofer Institute for Cell Therapy and Immunology in Leipzig and the German Primate Centre in Göttingen.

24 Apr 2020

Syphilis bacterium likely uses a single gene to evade immune attack

The bacterium that causes syphilis, Treponema pallidum, likely uses a single gene to escape the immune system, research from UW Medicine in Seattle suggests.

24 Apr 2020

Research shows how the immune system reacts to hepatitis C viruses

If a virus penetrates a cell, the immune system reacts immediately and produces the signaling protein interferon.

24 Apr 2020

Goblet cells in the human nasal passage may play key role in enabling COVID-19 infections

Two significant international studies involving hundreds of scientists, including a human geneticist at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that specific cells in the human nasal passage shaped like a champagne glass, known as goblet cells, may play a significant role in enabling COVID-19 infections.

24 Apr 2020

SARS-CoV-2 targets specific cells in the lung, nasal passage, and intestine

Now, the researchers from the Massachusetts Institute of Technology (MIT) have identified specific types of cells that are targets of the SARS-CoV-2 that causes the COVID-19 pandemic. The findings of the study published in the journal Cell may help in developing novel therapeutics to combat the deadly viral infection.

23 Apr 2020

Novel method may enable decentralized facilities to deliver faster COVID-19 test services

The COVID-19 pandemic has resulted in over 2.5 million confirmed cases worldwide and nearly over 170,000 deaths as of April 21 according to the World Health Organization.

23 Apr 2020

Study identifies key nose cells as likely COVID-19 virus entry points

Two specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells.

23 Apr 2020

Breakthrough discovery in HIV research opens path to new, better therapies

New research on the human immunodeficiency virus (HIV) structure has revealed a promising novel drug target for treating it.

23 Apr 2020

Researchers develop a faster visualization method for constructing pan-genome subgraphs

Kadir Dede and Dr. Enno Ohlebusch at Ulm University in Germany have devised a method for constructing pan-genome subgraphs at different granularities without having to wait hours and days on end for the software to process the entire genome.

23 Apr 2020

FUJIFILM Diosynth Biotechnologies Enters Strategic Partnership With OXGENE™ To Address Supply Bottlenecks In Gene Therapy Development And Manufacturing

FDB announced a strategic partnership with OXGENE™, an industry leader in the design and development of gene therapy technologies.

From OXGENE 23 Apr 2020

Many cells in human uterus carry 'cancer-driving' mutations that arise early in life

Many cells in the inner lining of the uterus carry 'cancer-driving' mutations that frequently arise early in life, report scientists from the Wellcome Sanger Institute, the University of Cambridge and their collaborators.

23 Apr 2020

Genes News and Research

Researchers identify a new risk factor for multiple neurodegenerative diseases

Antibiotic exposure and its priming effect on disease-causing bacteria

Researchers develop new method for remotely stimulating activity in deep brain regions

Prolonged corticosteroid treatment increases adrenal gland inflammation

SARS-CoV-2 readily infects human intestinal cells in a laboratory model

Scientists decode herpes simplex virus 1

Investigational drug may hold benefit for patients with lung and ovarian cancers

Talazoparib did not show overall survival benefit in patients with advanced BRCA-mutated breast cancer

Rice University looks to ‘trap and zap’ SARS-CoV-2 in wastewater

FAU scientists aim to develop a passive vaccine against COVID-19

Syphilis bacterium likely uses a single gene to evade immune attack

Research shows how the immune system reacts to hepatitis C viruses

Goblet cells in the human nasal passage may play key role in enabling COVID-19 infections

SARS-CoV-2 targets specific cells in the lung, nasal passage, and intestine

Novel method may enable decentralized facilities to deliver faster COVID-19 test services

Study identifies key nose cells as likely COVID-19 virus entry points

Breakthrough discovery in HIV research opens path to new, better therapies

Researchers develop a faster visualization method for constructing pan-genome subgraphs

FUJIFILM Diosynth Biotechnologies Enters Strategic Partnership With OXGENE™ To Address Supply Bottlenecks In Gene Therapy Development And Manufacturing

Many cells in human uterus carry 'cancer-driving' mutations that arise early in life

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