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Immunotherapy drug is safe and may benefit overall survival for patients with advanced NSCLC

For patients with advanced or metastatic non-small cell lung cancer (NSCLC) and limited performance status, an immune checkpoint inhibitor drug called durvalumab is safe and may benefit overall survival, according to a new eClinicalMedicine study by UPMC Hillman Cancer Center researchers.

21 Nov 2023

Sex-specific brain immunometabolism differences may underlie increased Alzheimer's risk in women

Cleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism – the interactions between the immune system and the ways cells create energy – may contribute to women's increased risk for the disease and its severity.

21 Nov 2023

Pitt researcher receives $1.95 million grant to study cell communication

Day by day, we communicate with our office colleagues to accomplish tasks that are necessary to function.

21 Nov 2023

Novel urine-based prognostic model promises to transform bladder cancer treatment

In a study published in the journal Genes & Diseases, researchers from Fudan University, have developed a novel urine-based prognostic model that promises to transform the management and treatment of bladder cancer.

21 Nov 2023

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

The impact of nicotinamide mononucleotide (NMN) on Clusters of differentiation 4+ (CD4+ ) Thymus cells (T cells) viz.

21 Nov 2023

Statins may reduce breast cancer mortality rates

The relationship between serological cholesterol levels, statin usage, and breast cancer (BC) mortality.

21 Nov 2023

Study reveals surprising role of cerebellar nuclei in associative learning

Associative learning was always thought to be regulated by the cortex of the cerebellum, often referred to as the "little brain".

20 Nov 2023

AI tools show promise in personalized cancer treatment, but lag behind human experts

Treating cancer is becoming increasingly complex, but also offers more and more possibilities. After all, the better a tumor's biology and genetic features are understood, the more treatment approaches there are.

20 Nov 2023

First-of-its-kind study reveals a new culprit in the formation of brain hemorrhages

A first-of-its-kind study led by the University of California, Irvine has revealed a new culprit in the formation of brain hemorrhages that does not involve injury to the blood vessels, as previously believed.

20 Nov 2023

New organoid model could lead to personalized treatments for colon-related diseases

A team at the Medical University of South Carolina and Cincinnati Children's has developed a sophisticated model for studying the diseased colon that could lead to the development of personalized treatments for colon-related diseases, such as cancer and inflammatory bowel disease (IBD).

20 Nov 2023

Novel 3D-printed implant could revolutionize infection control in surgery

A novel surgical implant developed by Washington State University researchers was able to kill 87% of the bacteria that cause staph infections in laboratory tests, while remaining strong and compatible with surrounding tissue like current implants.

20 Nov 2023

Researchers develop gene classifier to predict DCIS risk of cancer progression

A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.

20 Nov 2023

Groundbreaking technology developed to extract mesenchymal stem cells from pure bone marrow

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with the Agency for Science, Technology and Research (A*STAR) Bioprocessing Technology Institute (BTI) and National University Health System (NUHS), have developed a groundbreaking technology capable of extracting mesenchymal stem cells (MSCs) directly from pure bone marrow – also known as bone marrow aspirate (BMA), a pivotal source of MSCs – without dilution.

20 Nov 2023

Pigeon virus causes fatal neurological disease in young leukemia patient

A case report details a fatal neurologic disease in an immunocompromised toddler caused by pigeon avian paramyxovirus, underscoring the effectiveness of metagenomic testing in diagnosing complex infectious diseases.

19 Nov 2023

Stem-cell-derived brain cells hold promise for Alzheimer's, Parkinson's research

Researchers at the University of Wisconsin–Madison have identified a protein key to the development of a type of brain cell believed to play a role in disorders like Alzheimer's and Parkinson's diseases and used the discovery to grow the neurons from stem cells for the first time.

17 Nov 2023

Study reveals significant post-COVID meningitis resurgence

A team of scientists from the Institut Pasteur has used the database of the National Reference Center for Meningococci to trace the evolution of invasive meningococcal disease cases in France between 2015 and 2022, revealing an unprecedented resurgence in the disease after the easing of control measures imposed during the COVID-19 epidemic.

17 Nov 2023

New understanding of lung cancer cells' 'memories' suggests novel treatment approach

A new understanding of lung cancer cells' "memories" suggests a new strategy for improving treatment, Memorial Sloan Kettering Cancer Center (MSK) researchers have found.

17 Nov 2023

Researchers identify a promising new strategy for glaucoma cell replacement therapy

Glaucoma is one of the leading causes of blindness worldwide, and vision loss, due to the loss of retinal ganglion cells (RGCs), cannot currently be reversed with any treatment.

17 Nov 2023

RIT scientist earns NIH award to support research on building the next generation of drugs

Rochester Institute of Technology's Emiliano Brini, assistant professor in the School of Chemistry and Materials Science, has received an award from the National Institutes of Health (NIH) to support his research on building the next generation of drugs.

17 Nov 2023

Unraveling the immune system's response to nanoparticle drug delivery

To reduce the side effects associated with chemotherapy treatments, researchers have investigated the use of delivery systems that can take more drugs directly to the tumor. Ninh (Irene) La-Beck, Pharm.D., from the Department of Immunotherapeutics and Biotechnology at the Texas Tech University Health Sciences Center (TTUHSC) Jerry H. Hodge School of Pharmacy is one of those researchers.

17 Nov 2023

Cell News and Research

Immunotherapy drug is safe and may benefit overall survival for patients with advanced NSCLC

Sex-specific brain immunometabolism differences may underlie increased Alzheimer's risk in women

Pitt researcher receives $1.95 million grant to study cell communication

Novel urine-based prognostic model promises to transform bladder cancer treatment

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

Statins may reduce breast cancer mortality rates

Study reveals surprising role of cerebellar nuclei in associative learning

AI tools show promise in personalized cancer treatment, but lag behind human experts

First-of-its-kind study reveals a new culprit in the formation of brain hemorrhages

New organoid model could lead to personalized treatments for colon-related diseases

Novel 3D-printed implant could revolutionize infection control in surgery

Researchers develop gene classifier to predict DCIS risk of cancer progression

Groundbreaking technology developed to extract mesenchymal stem cells from pure bone marrow

Pigeon virus causes fatal neurological disease in young leukemia patient

Stem-cell-derived brain cells hold promise for Alzheimer's, Parkinson's research

Study reveals significant post-COVID meningitis resurgence

New understanding of lung cancer cells' 'memories' suggests novel treatment approach

Researchers identify a promising new strategy for glaucoma cell replacement therapy

RIT scientist earns NIH award to support research on building the next generation of drugs

Unraveling the immune system's response to nanoparticle drug delivery

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