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Assessing DDX53 as a potential early esophageal cancer antigen

A new research paper was published in Oncoscience (Volume 10) on November 10, 2023, entitled, "An immunoinformatics assessment of the cancer testis antigen, DDX53, as a potential early esophageal cancer antigen."

17 Nov 2023

Injectable grain-of-rice-sized glucose monitor could revolutionize diabetes management

The first glucose self-monitoring system created in 1970 weighed three pounds, was initially designed only for physicians' offices and needed a large drop of blood for a reading.

17 Nov 2023

Experts shed light on how autism affects the diagnosis, treatment of epilepsy and vice versa

Compared with the general population, epilepsy is more common in people with autism - and autism is more common in people with epilepsy. How can autism affect the diagnosis and treatment of epilepsy, and vice versa? Joy Mazur spoke to Dr. Colin Reilly and Dr. Stéphane Auvin.

17 Nov 2023

Researchers develop new method to detect protein aggregates in neurodegenerative diseases

Proteins misfolding and clumping together, a process known as aggregation, is a key feature seen in several neurological conditions, including Alzheimer's and Parkinson's diseases.

17 Nov 2023

Falk Trust awards $1.35 million to Case Western Reserve researchers for cancer and diabetic retinopathy treatments

A combined $1.35 million from the Dr. Ralph and Marian Falk Medical Research Trust was awarded to two researchers from the Case Western Reserve University School of Medicine to advance their work on finding more effective treatments - and better options - for two debilitating diseases.

17 Nov 2023

Nerve-immune system cross-talk: Key to zebrafish heart regeneration

Unlike humans, zebrafish can completely regenerate their hearts after injury. They owe this ability to the interaction between their nervous and immune systems, as researchers led by Suphansa Sawamiphak from the Max Delbrück Center now report in the journal Developmental Cell.

17 Nov 2023

Novel tool can help with analysis of single cell data

CITE-seq (cellular indexing of transcriptomes and epitopes) is an RNA sequencing-based method that simultaneously quantifies cell surface protein and transcriptomic data within a single cell readout.

17 Nov 2023

Uncontrolled growth as a cancer cell's weakness

Growth is a fundamental biological process and a prerequisite for living organisms to develop and reproduce. The processes of cell growth (i.e. the production of new biomass) and of cell division must be coordinated with each other.

17 Nov 2023

Green tea-silver nanoparticles: A promising weapon against superbugs

Once upon a time, people believed to be invincible against bacterial diseases, thanks to the antibiotics. Does this sound like a fairy tale? By all means! Nothing could be further from the truth.

17 Nov 2023

'AI virtual patients' diagnostic application revolutionizes medical education in Hong Kong

With the rapid development and extensive applications of generative artificial intelligence (AI) technology across various sectors, Dr Michael Co Tiong-hong from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), and Dr John Yuen Tsz-hon from the Department of Computer Science, HKU, have jointly developed Hong Kong's first 'AI virtual patients' diagnostic application for training medical students.

17 Nov 2023

Pioneering collaboration aims to fight against pancreatic cancer

In a significant global initiative coinciding with World Pancreatic Cancer Day on Thursday, November 16, the soon-to-launch Botton-Champalimaud Pancreatic Cancer Centre in Portugal, in partnership with the Jreissati Pancreatic Centre at Epworth in Australia and the Cancer Research UK Cambridge Centre - Pancreatic Cancer Programme in the United Kingdom, announces a pioneering collaboration.

17 Nov 2023

CMA clarifies cooperation on combination therapies to speed up patient access to vital treatments

The Competition and Markets Authority (CMA) has today issued a statement clarifying that certain types of engagements between competing drug firms working on 'combination therapies' will not be prioritized for investigation - making it easier for drug firms to work together to develop vital treatments for use in the NHS.

17 Nov 2023

Immunogenicity of insect-specific Zika virus-vectorized vaccine candidates

The immunogenicity, safety, and effectiveness of ARPV/ZIKV a chimeric insect-specific flavivirus (ISFV)-Zika vaccine.

17 Nov 2023

Most states ban shackling pregnant women in custody, yet many report being restrained

Ashley Denney was about seven months pregnant in 2022 when police handcuffed her during an arrest in Carroll County, Georgia.

17 Nov 2023

Promising new cancer therapy appears to be extremely potent against tuberculosis

A promising new cancer therapy also appears extremely potent against one of the world's most devastating infectious diseases: tuberculosis (TB).

16 Nov 2023

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

16 Nov 2023

Coffee and COVID: Study finds coffee inhibits SARS-CoV-2, offers new dietary defense strategy

Study discovers that coffee, especially its bioactive compounds like chlorogenic acids, can inhibit SARS-CoV-2 entry and reduce ACE2 and TMPRSS2 levels, indicating that coffee intake might be a potential dietary strategy for COVID-19 prevention.

16 Nov 2023

New insights into how cells maintain their identity over generations

Every cell in the human body contains the same genetic instructions, encoded in its DNA. However, out of about 30,000 genes, each cell expresses only those genes that it needs to become a nerve cell, immune cell, or any of the other hundreds of cell types in the body.

16 Nov 2023

Diabetes linked to higher colorectal cancer risk in low-income African-Americans, study shows

JAMA Network Open study finds that diabetes increases colorectal cancer risk among low-income African-American individuals, with stronger associations observed in women, smokers, and those recently diagnosed, suggesting that glycemic control and colonoscopy screenings could mitigate risk.

16 Nov 2023

B-BiTE modality enhances anti-myeloma effects of clinically available antibodies

Multiple myeloma still appears to be an incurable hematological malignancy. One of the reasons is that myeloma cells can be heterogenous and acquire resistance after anti-myeloma treatment.

16 Nov 2023

Cell News and Research

Assessing DDX53 as a potential early esophageal cancer antigen

Injectable grain-of-rice-sized glucose monitor could revolutionize diabetes management

Experts shed light on how autism affects the diagnosis, treatment of epilepsy and vice versa

Researchers develop new method to detect protein aggregates in neurodegenerative diseases

Falk Trust awards $1.35 million to Case Western Reserve researchers for cancer and diabetic retinopathy treatments

Nerve-immune system cross-talk: Key to zebrafish heart regeneration

Novel tool can help with analysis of single cell data

Uncontrolled growth as a cancer cell's weakness

Green tea-silver nanoparticles: A promising weapon against superbugs

'AI virtual patients' diagnostic application revolutionizes medical education in Hong Kong

Pioneering collaboration aims to fight against pancreatic cancer

CMA clarifies cooperation on combination therapies to speed up patient access to vital treatments

Immunogenicity of insect-specific Zika virus-vectorized vaccine candidates

Most states ban shackling pregnant women in custody, yet many report being restrained

Promising new cancer therapy appears to be extremely potent against tuberculosis

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Coffee and COVID: Study finds coffee inhibits SARS-CoV-2, offers new dietary defense strategy

New insights into how cells maintain their identity over generations

Diabetes linked to higher colorectal cancer risk in low-income African-Americans, study shows

B-BiTE modality enhances anti-myeloma effects of clinically available antibodies

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