Genes News and Research

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Scientists model human CMV-induced microcephaly using brain organoids

A City of Hope scientist is one step closer to discovering what weakens a pathogen that appears to cause babies to be born with abnormally small heads.

30 Mar 2020

What takes so long? A behind-the-scenes look at the steps involved in COVID-19 testing

After a slow start, testing for COVID-19 has ramped up in recent weeks, with giant commercial labs jumping into the effort, drive-up testing sites established in some places and new types of tests approved under emergency rules set by the Food and Drug Administration.

30 Mar 2020

Gene that could affect the progress of ALS discovered

Researchers from the Zuckerman Institute at Columbia University have successfully found a gene that could work towards accelerating the progression of ALS or amyotrophic lateral sclerosis. The study titled, "The loss of TBK1 kinase activity in motor neurons or in all cell types differentially impacts ALS disease progression in SOD1 mice," was published in the latest issue of the journal Neuron.

29 Mar 2020

Researchers examining gene coexpression and brain connectivity in females with ASD

Allison Jack, Assistant Professor, Psychology, is examining gene coexpression and brain connectivity in females with autism spectrum disorder.

27 Mar 2020

Study shows how copper boosts pig growth

Pigs have better feed conversion rates with copper in their diets, but until now, scientists didn't fully understand why.

27 Mar 2020

Scientists discover a completely new antibiotic resistance gene

Aminoglycoside antibiotics are critically important for treating several types of infections with multi-resistant bacteria.

27 Mar 2020

Global scientific collaboration produces first genetic map of the cerebral cortex

The cerebral cortex is the relatively thin, folded, outer "gray matter" layer of the brain crucial for thinking, information processing, memory, and attention.

27 Mar 2020

Microbiome could help identify pre-cancer risk in women with HPV

A new study published in the open-access journal PLOS Pathogens in March 2020 reports the possible use of the bacteria Gardnerella found in the cervix and vagina of women with Human papillomavirus (HPV) infection, as a marker of precancerous change. The findings could help to find new methods of treatment that involve inducing changes in the microbiome to arrest the course of the disease.

26 Mar 2020

Removing a gene prevents Type 1 diabetes in mice by disguising beta cells

Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new UW-Madison study shows.

26 Mar 2020

Targeting specific histone deacetylase may be novel therapeutic strategy for NSCLC

The survival rates for patients with non-small cell lung cancer have improved greatly over the past decade thanks to several new targeted treatment options for patients.

26 Mar 2020

Highly focused radiation may slow disease progression in men with oligometastatic prostate cancer

Highly focused, intense doses of radiation called stereotactic ablative radiation (SABR) may slow progression of disease in a subset of men with hormone-sensitive prostate cancers that have spread to a few separate sites in the body, according to results of a phase II clinical trial of the therapy.

26 Mar 2020

Jumping genes help make functional brain cells in a lab dish

The process of making functional brain cells in a lab dish requires the precise activation of selfish genetic elements known as LINE-1 (L1) retrotransposons.

26 Mar 2020

Finding new treatments for muscular dystrophy with CRISPR-Cas9

A new study out of Boston's Children's Hospital has used the gene-editing tool CRISPR-Cas9 to explore the fatal genetic condition called facioscapulohumeral dystrophy (FSHD, one of the family of muscular dystrophies), and to test out the potential utility of various genes involved in this disorder. The research is published in the journal Science Translational Medicine.

25 Mar 2020

Researchers aim to find the genetic basis of severe coronavirus infection in young people

Hundreds of clinicians worldwide are banding together in an effort to study some types of severe cases of the new coronavirus disease.

25 Mar 2020

A genetic toolkit to produce multifunctional magnetic nanoparticles

Magnetic bacteria might soon be used for the production of novel biomaterials. A team of microbiologists at the University of Bayreuth led by Prof. Dr. Dirk Schüler developed a modular system for the genetic reprogramming of bacteria, thereby turning the organisms into cell factories for multifunctional magnetic nanoparticles that combine various useful functions and properties.

25 Mar 2020

Combination produces more proliferative, enduring central memory T cells for cellular therapy

Treating T cells harvested from a patient with a combination of an epigenetic drug and a cytokine while expanding the cells in the lab re-programs them into a stronger T cell type that persists longer than its comrades, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Immunology Research, a journal of the American Association for Cancer Research.

25 Mar 2020

Municipal solid waste treatment systems could be a reservoir of antibiotic-resistance genes

Municipal solid waste is trash -- such as plastic, food scraps and lawn clippings -- that goes into garbage bins and doesn't get recycled.

25 Mar 2020

YAP signal pathway plays a vital role in the onset of head-and-neck cancer

Joint research between Kobe University and National Hospital Organization Kyushu Cancer Center has revealed that mice with mutations in the YAP signal pathway develop head-and-neck cancer over an extremely short period of time (world's fastest cancer onset mouse model), indicating that this pathway plays a crucial role in the onset of these cancers.

25 Mar 2020

Study explores genetic mechanisms underlying resistance to leishmaniasis

In an article published in Scientific Reports, researchers affiliated with the University of São Paulo in Brazil describe experiments performed with mice that show how genetic factors can determine whether an individual is susceptible or resistant to leishmaniasis.

24 Mar 2020

Humans are not the first to exploit benefits of CRISPR technique, research shows

In recent years, the development of CRISPR technologies and gene-editing scissors in particular have taken the world by storm. Indeed, scientists have learned how to harness these clever natural systems in the biotech and pharmaceutical industries, among other areas.

24 Mar 2020

Genes News and Research

Scientists model human CMV-induced microcephaly using brain organoids

What takes so long? A behind-the-scenes look at the steps involved in COVID-19 testing

Gene that could affect the progress of ALS discovered

Researchers examining gene coexpression and brain connectivity in females with ASD

Study shows how copper boosts pig growth

Scientists discover a completely new antibiotic resistance gene

Global scientific collaboration produces first genetic map of the cerebral cortex

Microbiome could help identify pre-cancer risk in women with HPV

Removing a gene prevents Type 1 diabetes in mice by disguising beta cells

Targeting specific histone deacetylase may be novel therapeutic strategy for NSCLC

Highly focused radiation may slow disease progression in men with oligometastatic prostate cancer

Jumping genes help make functional brain cells in a lab dish

Finding new treatments for muscular dystrophy with CRISPR-Cas9

Researchers aim to find the genetic basis of severe coronavirus infection in young people

A genetic toolkit to produce multifunctional magnetic nanoparticles

Combination produces more proliferative, enduring central memory T cells for cellular therapy

Municipal solid waste treatment systems could be a reservoir of antibiotic-resistance genes

YAP signal pathway plays a vital role in the onset of head-and-neck cancer

Study explores genetic mechanisms underlying resistance to leishmaniasis

Humans are not the first to exploit benefits of CRISPR technique, research shows

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