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Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

Researchers assessed the association between obesity and T cell frequencies specific to the SARS-CoV-2 antigen.

1 Jul 2022

Casirivimab/imdevimab improve outcomes in early COVID-19

A new Viruses study determines the effect of casirivimab/imdevimab on IFN-1 and cytokines during SARS-CoV-2 infection.

29 Jun 2022

Study finds SARS-CoV-2 E protein antagonizes BET protein-mediated antiviral responses during infection

Researchers assessed the impact of SARS-CoV-2 envelope protein on the bromodomain and extraterminal domain (BET) proteins.

29 Jun 2022

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

Scientists from China have recently deciphered the genetic network and biological mechanisms associated with COVID-19 myocarditis using bioinformatic methods.

28 Jun 2022

New technique offers higher-precision scRNA-seq data than current technologies

The advent of single-cell RNA sequencing (scRNA-seq) has revolutionized the fields of medicine and biology by providing the ability to study the inner workings of thousands of cells at one go.

28 Jun 2022

The potential of DNA-based SARS-CoV-2 vaccine candidates

Researchers evaluated the immunogenicity of DNA-based candidate vaccines against SARS-CoV-2 in mice.

28 Jun 2022

New tissue model helps trace the steps involved in liver regeneration

The human liver has amazing regeneration capabilities: Even if up to 70 percent of it is removed, the remaining tissue can regrow a full-sized liver within months.

27 Jun 2022

Study investigates the virological attributes of Omicron in a Syrian hamster model

Researchers investigated the virological attributes of SARS‐CoV‐2 new variant of concern Omicron in a Syrian hamster model.

27 Jun 2022

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

AbbVie today announced the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) recommended the approval of upadacitinib (RINVOQ® 15 mg, once daily) for the treatment of active non-radiographic axial spondyloarthritis (nr‑axSpA) in adult patients with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI), who have responded inadequately to nonsteroidal anti-inflammatory drugs (NSAIDs).*

27 Jun 2022

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

In a recent study posted to the medRxiv* pre-print server, researchers in the United States characterized differential host immune responses in acute coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) to inform future development of novel biomarkers for both diseases.

23 Jun 2022

Mild COVID causes increase in neurotoxic metabolites

In a recent study posted to the bioRxiv* pre-print server, researchers investigated the blood levels of neurotoxic metabolites in patients with mild coronavirus disease 2019 (COVID-19).

23 Jun 2022

Study links post-COVID symptoms with alterations in gut microbiota

A team of scientists has recently highlighted the significance of gut microbiota alterations induced by SARS-CoV-2 in triggering post-COVID-19 symptoms.

23 Jun 2022

Scientists evaluate JNK inhibitors in treating moderate to severe COVID-19 patients

Scientists have described the clinical outcomes in hospitalized COVID-19 patients who have been treated with JNK inhibitors together with standard of care.

22 Jun 2022

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

In a recent review published in Immunity, researchers explored potential mechanisms of neuro-immune pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

22 Jun 2022

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

A recent study published in the Cell Reports journal analyzed immune ecology at the placenta in mild or asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy.

22 Jun 2022

The effect of the COVID-19 BNT162b2 vaccine on semen parameters among semen donors

Researchers explored the impact of COVID-19 BNT162b2 (Pfizer) vaccinations on male fertility among semen donors in Israel.

21 Jun 2022

Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

Researchers comparatively assessed the generation of B lymphocyte-mediated antibody responses and T lymphocyte-mediated cellular responses between mRNA BNT162b vaccinees and mild COVID-19 patients.

21 Jun 2022

Cytokine News and Research

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

Casirivimab/imdevimab improve outcomes in early COVID-19

Study finds SARS-CoV-2 E protein antagonizes BET protein-mediated antiviral responses during infection

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

New technique offers higher-precision scRNA-seq data than current technologies

The potential of DNA-based SARS-CoV-2 vaccine candidates

New tissue model helps trace the steps involved in liver regeneration

Study investigates the virological attributes of Omicron in a Syrian hamster model

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

Mild COVID causes increase in neurotoxic metabolites

Study links post-COVID symptoms with alterations in gut microbiota

Scientists evaluate JNK inhibitors in treating moderate to severe COVID-19 patients

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

The effect of the COVID-19 BNT162b2 vaccine on semen parameters among semen donors

Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

How specific comorbidities impact severity of COVID-19

Researchers highlight the impact of macrophage subtypes on acute kidney injury to CKD transition

Implications of impaired type I interferon immunity and increasing COVID-19 severity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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