Antibodies News and Research

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Piramal's Healthcare invests USD 2.5 million to upgrade ADC manufacturing suites

Piramal's Healthcare vertical today announced that it is to invest USD 2.5 million at its FDA approved Grangemouth, UK, site to upgrade one of its antibody drug conjugate (ADC) manufacturing suites, from clinical phase to commercial grade, in response to customer demand.

26 Jul 2013

New species of adenovirus can spread from monkey to human, say researchers

Adenoviruses commonly infect humans, causing colds, flu-like symptoms and sometimes even death, but now UC San Francisco researchers have discovered that a new species of adenovirus can spread from primate to primate, and potentially from monkey to human.

26 Jul 2013

Randomized trial examines purging of tumor cells from stem cells prior to transplantation in neuroblastoma patients

Judith Villablanca, MD, of The Saban Research Institute of Children's Hospital Los Angeles, Susan Kreissman, MD, of Duke University Medical Center, and colleagues reported the results of a randomized, phase 3 clinical trial conducted by the Children's Oncology Group examining the effect of selectively removing (purging) tumor cells from blood stem cells before they are transplanted back into patients with high-risk neuroblastoma following high-dose chemotherapy.

25 Jul 2013

NIAID researchers discover monoclonal antibody can neutralize human norovirus

Researchers from the National Institute of Allergy and Infectious Diseases (NIAID) provide the first proof of concept data showing that a monoclonal antibody can neutralize human norovirus. This research, which could one day lead to effective therapies against the virus, was published online ahead of print in the Journal of Virology.

25 Jul 2013

Scientists develop simple, inexpensive and reliable method of detecting plague pathogen

Diagnosing the presence of Yersinia pestis, the cause of plague, may soon be easier than ever before. Scientists working with Peter Seeberger, Director at the Max Planck Institute of Colloids and Interfaces (MPIKG) in Potsdam and Professor at the Freie Universit-t Berlin, have come up with a simple, inexpensive and reliable method of detecting the bacterium.

25 Jul 2013

ProteinSimple introduces FluorChem R system with infrared detection capabilities

ProteinSimple today introduced the FluorChem R system as the next member of the FluorChem product family. The FluorChem R system is a fully integrated, multimode gel and Western blot imager with chemiluminescent, fluorescent, and infrared detection capabilities.

From ProteinSimple 24 Jul 2013

Report shows that fatal rabies virus is transmitted through transplanted kidney

An investigation into the source of a fatal case of raccoon rabies virus exposure indicates the individual received the virus via a kidney transplant 18 months earlier, findings suggesting that rabies transmitted by this route may have a long incubation period, and that although solid organ transplant transmission of infectious encephalitis is rare, further education to increase awareness is needed, according to a study in the July 24/31 issue of JAMA.

24 Jul 2013

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

P53 is a tumor suppressor gene. The gene encodes for a protein that monitors the state of the cell. If something goes wrong, it stops the cell from dividing or causes the cell to commit suicide. I call it the “guardian of the genome” as it is the molecule that seems to keep cells normal. It is one of our big defenses against cancer.

22 Jul 2013

Fujikura to exercise option to license Cellmid’s midkine diagnostic technology

Cellmid Limited has received confirmation that Fujikura Kasei Co Ltd (Fujikura) will exercise its Option to licence the midkine (MK) diagnostic technology by paying the requisite JPY40 million (AUD 440,000) Milestone Fee.

22 Jul 2013

Protein on surface of human breast tumour cells may serve as drug target for breast cancer

Scientists have identified higher levels of a receptor protein found on the surface of human breast tumour cells that may serve as a new drug target for the treatment of breast cancer.

19 Jul 2013

American Crystallographic Association analysis may help researchers design vaccine against HIV/AIDS

Designing an effective HIV/AIDS vaccine is something of a paradox: a good vaccine would be safe and look enough like HIV to kick-start the immune system into neutralizing the virus - but the problem is that this is exactly what the human immune system has trouble doing even when it's exposed to the real thing.

19 Jul 2013

Ablynx initiates additional Phase I studies with anti-RSV Nanobody ALX-0171

Activaero GmbH, the therapeutic area specialist for respiratory diseases focusing on novel, pharmacoeconomically meaningful treatment solutions, today announced that its partner Ablynx NV has initiated additional Phase I studies with its anti-RSV Nanobody ALX-0171 using Activaero's FAVORITE inhalation approach.

18 Jul 2013

Plague detection through anti-carbohydrate antibodies could lead to rapid diagnosis

Even today, the lives of humans and animals are claimed by plague. A new antibody-based detection method can be used to reliably and sensitively identify plague in patient serum and other biological samples.

18 Jul 2013

CHOP-led research increases numbers of patients who could be treated with gene therapy

Gene therapy researchers have produced a bioengineered decoy that fools the immune system and prevents it from mistakenly defeating the benefits delivered by a corrective gene.

18 Jul 2013

AbGenomics raises $9.6M for advancing therapeutic antibodies for autoimmune diseases, cancers

AbGenomics International announced today that it has raised $9.6 million in current financing round.

18 Jul 2013

Researchers develop pocket-sized drug test for use in health care settings

The National Institute on Drug Abuse has agreed to award $2.1 million to Lidong Qin, Ph.D., and Ping Wang, Ph.D., of the Houston Methodist Research Institute to develop a pocket-sized drug test for use in health care settings.

17 Jul 2013

Weill Cornell reports new findings from IVIG Phase 3 trial in Alzheimer's disease at AAIC 2013

Weill Cornell Medical College neurologist Dr. Norman Relkin reported new findings today from the Phase 3 clinical trial of IVIG (intravenous immunoglobulin) in mild to moderate Alzheimer's disease at the Alzheimer's Association International Conference in Boston, Mass.

16 Jul 2013

ADC Therapeutics, BZL Biologics sign licensing deal for antibody against PSMA-positive prostate cancers

ADC Therapeutics Sarl, a portfolio company of Auven Therapeutics and the oncology drug development company specializing in proprietary antibody drug conjugates, and BZL Biologics LLC, of New York, today announced an exclusive licensing and collaboration agreement for an antibody against PSMA-positive prostate cancers.

15 Jul 2013

Infrared light allows characterization of pathogens

The bacterium Staphylococcus aureus (S. aureus) is commonly found in nature and frequently colonizes the skin and the upper respiratory tract of humans. A healthy immune system can fight the microorganism but once the immune system is weakened the pathogen can spread and lead to life-threatening diseases of the lungs, the heart and other organs.

15 Jul 2013

Scientists successfully transplant insulin-producing cells from one species to another

In the first step toward animal-to-human transplants of insulin-producing cells for people with type 1 diabetes, Northwestern Medicine- scientists have successfully transplanted islets, the cells that produce insulin, from one species to another. And the islets survived without immunosuppressive drugs.

15 Jul 2013

Antibodies News and Research

Piramal's Healthcare invests USD 2.5 million to upgrade ADC manufacturing suites

New species of adenovirus can spread from monkey to human, say researchers

Randomized trial examines purging of tumor cells from stem cells prior to transplantation in neuroblastoma patients

NIAID researchers discover monoclonal antibody can neutralize human norovirus

Scientists develop simple, inexpensive and reliable method of detecting plague pathogen

ProteinSimple introduces FluorChem R system with infrared detection capabilities

Report shows that fatal rabies virus is transmitted through transplanted kidney

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

Fujikura to exercise option to license Cellmid’s midkine diagnostic technology

Protein on surface of human breast tumour cells may serve as drug target for breast cancer

American Crystallographic Association analysis may help researchers design vaccine against HIV/AIDS

Ablynx initiates additional Phase I studies with anti-RSV Nanobody ALX-0171

Plague detection through anti-carbohydrate antibodies could lead to rapid diagnosis

CHOP-led research increases numbers of patients who could be treated with gene therapy

AbGenomics raises $9.6M for advancing therapeutic antibodies for autoimmune diseases, cancers

Researchers develop pocket-sized drug test for use in health care settings

Weill Cornell reports new findings from IVIG Phase 3 trial in Alzheimer's disease at AAIC 2013

ADC Therapeutics, BZL Biologics sign licensing deal for antibody against PSMA-positive prostate cancers

Infrared light allows characterization of pathogens

Scientists successfully transplant insulin-producing cells from one species to another

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