Angioplasty News and Research

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In angioplasty procedures, a balloon is fed through a catheter and used to prop open an artery that has become narrowed or blocked. In cases where stenting is appropriate, a stent mounted on a balloon is inserted and inflation of the balloon expands the stent against the blocked artery wall to hold the vessel open. The balloon is then deflated and the catheter is withdrawn. Stent treatment of arteries holds them open and improves blood flow to the heart. In cases where post-dilatation is needed, a high-pressure balloon is inflated inside a stent to help better place the stent against the vessel wall.

Driving times and distances to hospitals with percutaneous coronary intervention in the United States

Diverting ambulances with patients suffering a heart to a hospital providing emergency angioplasty rather than a closer hospital with no ability to provide this specialized care, may be feasible for the majority of Americans

15 Mar 2006

Innovative treatment for critical limb ischemia

A new randomized study presented at the American College of Cardiology's 55th Annual Scientific Session investigates an innovative treatment for critical limb ischemia, or lack of arterial blood supply and oxygen to the legs, using a therapeutic approach to generate new blood vessels.

14 Mar 2006

Researchers find viable new sources for stem cell transplants to the heart

Stem cell transplantation is among one of the most exciting and hotly debated areas of medical research today. While the promise of personalized medicine and effective treatments for debilitating diseases drive progress in this area, moral and ethical dilemmas about embryonic cells continues to cloud the field.

14 Mar 2006

Creative new therapies for atherosclerotic disease

Patients with a build-up of plaque in arteries in the heart, brain and leg face a high risk of major cardiovascular complications.

14 Mar 2006

Clopidogrel reduces risk of adverse events for patients with acute coronary syndromes undergoing balloon angioplasty

Patients with acute coronary syndromes who were pre-treated with the anti-platelet agent clopidogrel before undergoing a procedure such as balloon angioplasty or stent placement had a reduced risk of adverse events if they received the anti-clotting drug abciximab

14 Mar 2006

Stents that release the drug paclitaxel to treat stenosis more effective than radiation therapy

Insertion of stents that release the drug paclitaxel to treat stenosis within an implanted bare-metal stent in a coronary artery reduces the risk of subsequent re-narrowing within the stent, when compared with treatment using intra-coronary radiation

13 Mar 2006

Health disparities in heart attack hospital transfer patterns

Older, female and minority patients rushed to community hospitals with acute heart attacks are less likely to be transferred to a larger hospital that offers procedures to immediately open clogged arteries, Duke University Medical Center cardiologists have found.

13 Mar 2006

How close Americans live to hospitals that can perform angioplasty

University of Michigan and Yale analysis shows that within 60 minutes, 80 percent of Americans could reach a hospital that can do emergency angioplasty.

9 Mar 2006

Achieving rapid door-to-balloon times: How top hospitals improve complex clinical systems

Some of the key elements for success in the rapid treatment of heart attacks have been identified by researchers at Yale School of Medicine in a recent issue of Circulation: Journal of the American Heart Association.

1 Mar 2006

Bone marrow stem cells do not improve cardiac function in heart attack patients

There has been increasing evidence that stem cells contribute to regeneration of cardiac tissue and the development of new blood vessels following a heart attack, thus opening up new prospects for stem-cell based therapies.

1 Mar 2006

Enhanced external counterpulsation (EECP) reduces angina

Patients with angina (chest pain) and left ventricular dysfunction respond very well to treatment using enhanced external counterpulsation (EECP), with little or no future heart failure events, according to researchers from the Cardiovascular Institute at the University of Pittsburgh Medical Center (UPMC).

1 Mar 2006

Treatment of severe coronary artery disease with angioplasty/coronary stenting a viable alternative to bypass surgery

Severe stenosis (blockage) to the left main coronary artery - a condition commonly called a "widow-maker"- can result in sudden death. For nearly 30 years, the gold standard for treatment has been coronary artery bypass surgery (CABG).

1 Mar 2006

Coronary stents that release the drugs sirolimus or paclitaxel produce similar results

Use of coronary stents that release the drugs sirolimus or paclitaxel produced similar results in patients with new coronary artery lesions, according to a study in JAMA: The Journal of the American Medical Association.

24 Feb 2006

Cutting angioplasty risks

Significant gains made through multi-hospital cooperative effort led by U-M Cardiovascular Center and funded by Blue Cross Blue Shield of Michigan.

16 Feb 2006

Stem cell injections may help those with severe peripheral artery disease

Indiana University School of Medicine scientists have begun a unique clinical trial using stem cell injections as a treatment that could offer hope to tens of thousands of people who face sores, ulcers and even amputations due to severe peripheral artery disease.

14 Feb 2006

Patients checking into a top rated hospital have a 27 percent lower chance of mortality

Patients checking into a hospital rated in the top five percent in the country have, on average, a 27 percent lower chance of mortality and a 14 percent lower risk of complications, according to a study released today by HealthGrades, the leading independent healthcare ratings company.

7 Feb 2006

Women at greater risk of subsequent stroke than men

Among patients who have suffered a single stroke, researchers at the University of Pennsylvania School of Medicine, along with colleagues at other institutions, have found that severe stenosis, or narrowing, of the arteries in the head represents a major risk factor for the development of a subsequent stroke.

27 Jan 2006

University of Florida researchers restore vitality to cells in lab experiments

University of Florida researchers say primitive cells that act like molecular maintenance men - traveling throughout the body to repair damaged blood vessels - become too rigid to move in patients with diabetes, fueling the disease's vascular complications.

25 Jan 2006

FDA fast track status for Alfimeprase

Nuvelo Inc. today announced that it has been granted fast track designation by the U.S. Food and Drug Administration (FDA) for its lead product candidate, alfimeprase, for the treatment of acute peripheral arterial occlusion (PAO), or "leg attack."

23 Jan 2006

Emergency angioplasty better than clot-busting drugs

Across America, hospitals large and small have been racing to offer angioplasty and other minimally invasive treatments to open blocked heart arteries. But not all of them have the ability to do it on an emergency basis, performing angioplasty around the clock on heart attack patients. So, during evenings and weekends, many hospitals use clot-busting drugs instead.

16 Jan 2006