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Facets of SARS-CoV-2 infection and animal models

A new study in the journal Frontiers in Cell and Developmental Biology discusses the ribonucleic acid (RNA) genome of the virus, and the mechanisms by which it establishes infection within the host cell. The researchers also summarize the development of animal models of COVID-19, which will both help understand the clinical features of the illness, and indicate new approaches for the treatment of the infection.

21 May 2021

Researchers evaluate risk of developing new clinical conditions after acute phase of COVID-19 infection

One in 7 (14%) adults with coronavirus infection developed at least one new condition that required medical care during the post-acute phase of illness, which is 5% higher than adults with no coronavirus infection in 2020, finds a US study published by The BMJ today.

21 May 2021

Researchers explore virtual reality technology for treating chronic pain

Researchers at the University of East Anglia are launching a new project to see whether virtual reality could help with the treatment of chronic pain.

21 May 2021

Study demonstrates the negative effects of HERV activation on human brain development

Since our ancestors infected themselves with retroviruses millions of years ago, we have carried elements of these viruses in our genes - known as human endogenous retroviruses, or HERVs for short.

21 May 2021

Emotional support animals can provide quantifiable benefits to people with serious mental illness

A team led by a social work researcher at The University of Toledo has published the first empirical evidence that emotional support animals can provide quantifiable benefits to individuals with serious mental illness who are experiencing depression, anxiety and loneliness.

21 May 2021

Young Latinx adults who experience heart-focused anxiety face greater risk for mental health disorders

For coffee drinkers, a common scenario might involve drinking an extra cup only to end up with a racing heart and a subtle reminder to themselves to cut down the caffeine.

21 May 2021

Medicaid-Medicare partnership could cover lifesaving medications for hepatitis C

Untreated hepatitis C can lead to serious and life-threatening health problems like cirrhosis and liver cancer. Direct-acting antiviral therapies introduced in recent years are highly effective, with cure rates above 95%.

21 May 2021

New peptides allow cannabis-derived drugs to fight pain in mice without side effects

An international team, led by researchers from Pompeu Fabra University (UPF) in Barcelona, Spain, David Andreu and Rafael Maldonado, has developed a peptides family that allows delta-9-tetrahydrocannabinol (THC), the main component of Cannabis sativa, to fight pain in mice without side effects.

20 May 2021

Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

Results from the VOYAGE study of dupilumab (Dupixent) showed that the monoclonal antibody significantly reduced exacerbations in children ages 6-11 with uncontrolled moderate-to-severe asthma, compared to placebo, according to research presented at the ATS 2021 International Conference. VOYAGE (NCT02948959) is a recently completed randomized, placebo-controlled double-blind multicenter phase 3 clinical trial, that took place in a number of countries.

20 May 2021

About two-fifths of Medicare beneficiaries with COPD have limited access to pulmonary rehabilitation services

Approximately two-fifths of Medicare beneficiaries with chronic obstructive pulmonary disease (COPD) have limited access to pulmonary rehabilitation services due to their distance from rehab centers, according to research presented at the ATS 2021 International Conference.

20 May 2021

Despite pandemic, Newsom declines to boost local public health budgets — again

In spite of a pandemic that has killed about 62,000 Californians — more than enough to pack Dodger Stadium — Gov. Gavin Newsom has again declined to boost the budgets of the state's underfunded and understaffed local public health departments.

20 May 2021

Extensive cancer research data to be presented at the 2021 ASCO Annual Meeting

Rutgers Cancer Institute of New Jersey, a leader in cutting-edge clinical trials and health outcomes analyses and a designated Comprehensive Cancer Center by the National Cancer Institute, together with RWJBarnabas Health, today announced that data from its cancer clinical research program will be presented at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, to be held virtually from June 4-8.

20 May 2021

UB pharmacy researcher to design real-time algorithm to reduce hospital readmission rates for COPD patients

To lower hospital readmission rates for patients with chronic obstructive pulmonary disease (COPD), University at Buffalo pharmacy researcher David Jacobs has received a $962,000 award from the National Heart, Lung, and Blood Institute to develop a real-time readmission risk prediction algorithm.

20 May 2021

Triple-drug therapy can reduce asthma exacerbations, improve control without major adverse events

Researchers have found that the inclusion of a third drug to commonly used dual-drug inhalers can reduce asthma exacerbations and improve control over the disease in children, adolescents, and adults with moderate-to-severe asthma.

20 May 2021

Four months of multi-drug therapy for tuberculosis is as effective as standard regimen

Four months of multi-drug therapy that included rifapentine and moxifloxacin treated active tuberculosis (TB) as effectively as the standard six-month regimen in a multinational study, cutting treatment time by a third.

20 May 2021

The effects of SARS-CoV-2 vaccination on pregnancy and birth

The severe impact of this infection has given rise to a study by Theiler et al. (2021), which investigated the effects of SARS-CoV-2 vaccination in pregnancy in order to examine the protection it could provide to combat the infection.

19 May 2021

Antithrombotic endothelial dysfunction is prevented by Tie2 activation in severe COVID-19

Researchers from the US recently assessed if severe COVID-19 is linked to procoagulant dysfunction of the endothelium and changes in the Tie2-angiopoietin axis. They assessed circulating endothelial markers in a study cohort of 98 patients with mild, moderate, or severe COVID-19. This study is published on the medRxiv* preprint server.

19 May 2021

Cognitive, behavioral therapy may produce more significant outcomes for obese people

Quality of life relating to physical and mental health can be a key element in the treatment of obese adults.

19 May 2021

A study reports the first case of an upper extremity deep vein thrombosis (DVT) recurrence due to COVID-19 infection

Researchers have reported the first case of COVID-19 triggering a rare occurrence of potentially severe blood clots forming in the arms.

19 May 2021

Randomized clinical trials compare effects of coronary revascularization versus medical therapy alone

A rigorous meta-analysis of randomized clinical trials (RCTs) that compared the effects of medical therapies alone with medical therapies plus revascularization in patients with stable ischemic heart disease (SIHD) was presented at EuroPCR on May 18, 2021.

19 May 2021

Chronic News and Research

Facets of SARS-CoV-2 infection and animal models

Researchers evaluate risk of developing new clinical conditions after acute phase of COVID-19 infection

Researchers explore virtual reality technology for treating chronic pain

Study demonstrates the negative effects of HERV activation on human brain development

Emotional support animals can provide quantifiable benefits to people with serious mental illness

Young Latinx adults who experience heart-focused anxiety face greater risk for mental health disorders

Medicaid-Medicare partnership could cover lifesaving medications for hepatitis C

New peptides allow cannabis-derived drugs to fight pain in mice without side effects

Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

About two-fifths of Medicare beneficiaries with COPD have limited access to pulmonary rehabilitation services

Despite pandemic, Newsom declines to boost local public health budgets — again

Extensive cancer research data to be presented at the 2021 ASCO Annual Meeting

UB pharmacy researcher to design real-time algorithm to reduce hospital readmission rates for COPD patients

Triple-drug therapy can reduce asthma exacerbations, improve control without major adverse events

Four months of multi-drug therapy for tuberculosis is as effective as standard regimen

The effects of SARS-CoV-2 vaccination on pregnancy and birth

Antithrombotic endothelial dysfunction is prevented by Tie2 activation in severe COVID-19

Cognitive, behavioral therapy may produce more significant outcomes for obese people

A study reports the first case of an upper extremity deep vein thrombosis (DVT) recurrence due to COVID-19 infection

Randomized clinical trials compare effects of coronary revascularization versus medical therapy alone

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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