SARS CoV 2 News and Research

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Can the US keep covid variants in check? Here’s what it takes

The covid-19 variants that have emerged in the United Kingdom, Brazil, South Africa and now Southern California are eliciting two notably distinct responses from U.S. public health officials.

28 Jan 2021

Neurological and psychiatric complications six months after COVID-19 recovery

Researchers in the United Kingdom have aimed to determine the prevalence of patients who experience neurological and psychiatric conditions six months after recovering from COVID-19.

28 Jan 2021

Moderna vaccine shows robust suppression of SARS-CoV-2 infection in animal model

Researchers have demonstrated that the prime or prime-boost vaccination of Moderna vaccine in hamsters induced robust neutralizing antibodies, ameliorated weight loss, and suppressed SARS-CoV-2 replication in the airways.

28 Jan 2021

COVID-19 patients in high-altitude ICUs had improved survival in case study

A team of researchers in Ecuador and the U.K. found that high altitudes may be linked to improved COVID-19 survival – particularly among patients with no comorbidities.

28 Jan 2021

Viral ExoN regulates the rate of recombination in SARS-CoV-2

Researchers at Vanderbilt University Medical Center (VUMC) and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles' heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics.

28 Jan 2021

COVID-19 vaccines should be given to pregnant or breastfeeding people, argue experts

People who are pregnant, breastfeeding or trying to conceive should be offered the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine based on ethical grounds, argue authors of a commentary in CMAJ (Canadian Medical Association Journal).

28 Jan 2021

Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2

Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2, preventing expression of genes that encode proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, all of which are entry points for the virus.

28 Jan 2021

Study provides a detailed look at vulnerable sites on SARS-CoV-2

A new study led by scientists at La Jolla Institute for Immunology (LJI) suggests that T cells try to fight SARS-CoV-2 by targeting a broad range of sites on the virus--beyond the key sites on the virus's spike protein.

27 Jan 2021

New tool offers data-driven, precision medicine approach to help scientists better understand COVID-19

It is called PAGER-CoV, and it promises to be an important tool in finding therapies for COVID-19.

27 Jan 2021

Temperature, latitude correlate with COVID-19 cases and mortality rates

With cities around the globe locking down yet again amid soaring COVID-19 numbers, could seasonality be partially to blame? New research from the University of Illinois says yes.

27 Jan 2021

COVID-19 mortality rates higher in pregnant women than in similarly aged individuals

Contracting COVID-19 while pregnant can have deadly consequences for the mother, a new study published today in American Journal of Obstetrics and Gynecology shows.

27 Jan 2021

Biliverdin shields SARS-CoV-2 from host antibody response, study finds

A team of international scientists has recently revealed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with two heme metabolites, bilirubin and biliverdin, to escape the antibody-mediated host immune responses.

27 Jan 2021

Anakinra shows therapeutic potential in critically ill COVID-19 patients

A team of international scientists recently conducted an open-level clinical trial to investigate the effects of personalized immunotherapy on critically ill COVID-19 patients.

27 Jan 2021

CDC researchers back U.S. school re-openings but with strict COVID-19 regulations

As the U.S. continues to grapple with surging cases and the complex logistics of mass vaccination, is the country in a position to fully re-open its schools for in-person learning? Researchers at the Centers for Disease Control and Prevention (CDC) think so – notwithstanding a few very important caveats.

27 Jan 2021

Could spironolactone treat COVID-19-related pneumonia and pulmonary fibrosis?

Researchers have described the potential of the drug spironolactone, a potassium-sparing diuretic, and anti-androgen, in preventing or alleviating the severity of COVID-19 pneumonia, and in preventing pulmonary fibrosis.

27 Jan 2021

What do we know about the SARS-CoV-2 vaccines so far?

A new study surveys what we know so far about SARS-CoV-2 vaccine candidates from advanced clinical trials.

27 Jan 2021

Allarity Therapeutics announces plans to test antiviral activity of stenoparib drug

Allarity Therapeutics of Hørsholm, Denmark, today announced plans to further test the antiviral activity of stenoparib, its PARP inhibitor, against SARS-CoV-2 lineage B.1.1.7, also known as Coronavirus Variant B117 (the "British variant"), at the COVID-19 Testing Service Center (CTSC) of Northern Arizona University's Pathogen and Microbiome Institute (PMI), a leading U.S. infectious disease testing center.

27 Jan 2021

New ACR Steering Committee established to guide diagnostic testing during COVID-19 pandemic

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today announced the formation of the AMP COVID Response (ACR) Steering Committee to help coordinate and communicate the organization's continued efforts to guide diagnostic testing during the ongoing COVID-19 pandemic and preparations for future emerging outbreaks.

27 Jan 2021

SARS-CoV-2 spike may impair antigen presentation by CD8 T cells

A new study published on the bioRxiv preprint server aims to identify specific viral epitopes on the spike protein from various regions of the spike protein and the T cell responses they evoke.

27 Jan 2021

Rapid transmission of N501Y variants may be due to favorable effects on host receptor binding

Now, in new research posted to the preprint server bioRxiv*, scientists use an experimental structure of the Spike RBD domain co-crystallized with part of the ACE2 receptor and several in silico methods to analyze the possible impacts of three amino acid replacements (Spike K417N, E484K, N501Y) concerning ACE2 binding.

27 Jan 2021

SARS CoV 2 News and Research

Can the US keep covid variants in check? Here’s what it takes

Neurological and psychiatric complications six months after COVID-19 recovery

Moderna vaccine shows robust suppression of SARS-CoV-2 infection in animal model

COVID-19 patients in high-altitude ICUs had improved survival in case study

Viral ExoN regulates the rate of recombination in SARS-CoV-2

COVID-19 vaccines should be given to pregnant or breastfeeding people, argue experts

Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2

Study provides a detailed look at vulnerable sites on SARS-CoV-2

New tool offers data-driven, precision medicine approach to help scientists better understand COVID-19

Temperature, latitude correlate with COVID-19 cases and mortality rates

COVID-19 mortality rates higher in pregnant women than in similarly aged individuals

Biliverdin shields SARS-CoV-2 from host antibody response, study finds

Anakinra shows therapeutic potential in critically ill COVID-19 patients

CDC researchers back U.S. school re-openings but with strict COVID-19 regulations

Could spironolactone treat COVID-19-related pneumonia and pulmonary fibrosis?

What do we know about the SARS-CoV-2 vaccines so far?

Allarity Therapeutics announces plans to test antiviral activity of stenoparib drug

New ACR Steering Committee established to guide diagnostic testing during COVID-19 pandemic

SARS-CoV-2 spike may impair antigen presentation by CD8 T cells

Rapid transmission of N501Y variants may be due to favorable effects on host receptor binding

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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