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Research suggests laminin could play role in slowing progression of breast tumors

Cells are capable of translating mechanical changes into biological responses. This process is known as mechanotransduction and plays a fundamental role in the progression of solid tumors, such as breast cancer.

14 Sep 2023

Harnessing the extraordinary capabilities of bio-nanoantennae to target and kill brain tumors

Researchers have discovered a new way to target and kill cancer cells in hard-to-treat brain tumors using electrically charged molecules to trigger self-destruction, that could be developed into a spray treatment used during surgery.

14 Sep 2023

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

Patients with stage 1–3 non-small cell lung cancer (NSCLC) given a combination immunotherapy prior to surgery (neoadjuvant) had a better major pathological response (10% or less residual cancer) when the cancer was removed than those who took a single immunotherapy agent alone, according to results of a novel multicenter phase 2 NeoCOAST platform trial that included two investigators from the Johns Hopkins Kimmel Cancer Center and its Bloomberg-Kimmel Institute for Cancer Immunotherapy.

14 Sep 2023

Multi-omics study offers insights into psoriasis treatment

Researchers use a multi-omics approach combining immune cell-enriched scRNA-seq, microarray analysis, and immunohistochemistry to elucidate the translational role of anti-IL-17A in suppressing the autoimmune functions of T17 cells, thereby effectively treating human psoriasis.

14 Sep 2023

Reviving reservoirs: new findings shake up HIV treatment understanding

Researchers provide insight into the interaction between T lymphocytes and persisting reservoirs of HIV, with repercussions for harnessing effective, long-lasting responses to HIV eradication.

14 Sep 2023

A novel multi-epitope vaccine targeting extracellular proteins of Chlamydia pneumoniae

Researchers designed and evaluated a multi-epitope vaccine targeting the main outer membrane protein of Chlamydia pneumoniae using immunoinformatics.

14 Sep 2023

The anti-metastatic and anti-proliferation impact of dandelion extract on breast cancer cells

Researchers evaluated the anti-metastatic and anti-proliferative properties of all-trans retinoic acid (ATRA) and dandelion extract in breast cancer cells.

14 Sep 2023

Flexible Spatial Biology Solution for Up to 8-Plex Amplification in Two Days: CST Launches SignalStar™ Multiplex IHC

Cell Signaling Technology (CST), a life science discovery technology company and leading provider of antibodies, kits, and services, today announced the launch of its SignalStar Multiplex IHC technology, a revolutionary new tool for spatial biology research using mid-plex, high-throughput immunohistochemistry (IHC) assays.

From Cell Signaling Technology 14 Sep 2023

AACR Cancer Progress Report provides latest statistics on cancer research and treatment

Today, the American Association for Cancer Research (AACR) released the 13th edition of its annual Cancer Progress Report, which chronicles how basic, translational, and clinical cancer research and cancer-related population sciences - primarily supported by federal investments in the National Institutes of Health (NIH) and the National Cancer Institute (NCI) - remain vitally important to improving health and saving lives.

13 Sep 2023

COVID-19 doubles risk of early type 1 diabetes signs in high-risk children

New research in JAMA finds a temporal association between SARS-CoV-2 infections and the onset of islet autoimmunity, a precursor to type 1 diabetes, in genetically predisposed infants. The study underscores COVID-19 as a potential risk factor for the development of this form of diabetes in young children.

13 Sep 2023

Nine-year study reveals lipids' pivotal role in aging, health, and disease

This groundbreaking nine-year study used advanced mass spectrometry to analyze lipid profiles in human plasma, revealing dynamic changes tied to aging, insulin resistance, and viral infections. The findings suggest that specific lipid subclasses are crucial indicators and potential targets for treatment in human health and various diseases.

13 Sep 2023

Rasip1 gene found to be intimately involved in the creation of blood cells

Blood has long been a symbol of life and health, so it may be surprising that some aspects of blood production, i.e., hematopoiesis, remain incompletely understood.

13 Sep 2023

New Omicron subvariant BA.2.86: A master of immune escape but not taking over yet

Researchers have isolated a new SARS-CoV-2 Omicron subvariant, BA.2.86, revealing its ability to escape neutralizing antibodies five-fold greater than its ancestor strain. Despite its enhanced immune evasion capabilities, BA.2.86 has not shown a significant difference in spread compared to other current variants.

13 Sep 2023

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops.

13 Sep 2023

Interferon-gamma essential for lung-resident memory B cell development after influenza infection

During a bout of influenza, B cells interact with other immune cells and then take different paths to defend the body.

13 Sep 2023

Innovative technique provides unparalleled insight into autism pathology

Does the human brain have an Achilles heel that ultimately leads to Autism? With a revolutionizing novel system that combines brain organoid technology and intricate genetics, researchers can now comprehensively test the effect of multiple mutations in parallel and at a single-cell level within human brain organoids.

13 Sep 2023

Cell News and Research

Research suggests laminin could play role in slowing progression of breast tumors

Harnessing the extraordinary capabilities of bio-nanoantennae to target and kill brain tumors

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

Multi-omics study offers insights into psoriasis treatment

Reviving reservoirs: new findings shake up HIV treatment understanding

A novel multi-epitope vaccine targeting extracellular proteins of Chlamydia pneumoniae

The anti-metastatic and anti-proliferation impact of dandelion extract on breast cancer cells

Flexible Spatial Biology Solution for Up to 8-Plex Amplification in Two Days: CST Launches SignalStar™ Multiplex IHC

AACR Cancer Progress Report provides latest statistics on cancer research and treatment

COVID-19 doubles risk of early type 1 diabetes signs in high-risk children

Nine-year study reveals lipids' pivotal role in aging, health, and disease

Rasip1 gene found to be intimately involved in the creation of blood cells

New Omicron subvariant BA.2.86: A master of immune escape but not taking over yet

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

Interferon-gamma essential for lung-resident memory B cell development after influenza infection

Innovative technique provides unparalleled insight into autism pathology

Study helps explain why solid tumors often spread to the spine

A family of weird proteins hijacks plants’ cellular plumbing

Researchers receive £2.66M to test new immunotherapeutic strategy for non-small cell lung cancer

Cerebellar inhibitory interneurons essential for fear memory, study finds

What are the challenges of cell line development? eBook

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