Embryo News and Research

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UH biologists developing strategies to help regenerate heart muscle cell formation

Cardiovascular diseases are the leading cause of death in the U.S. With one in every four deaths occurring each year, the five-year survival rate after a heart attack is worse than most cancers.

10 Aug 2016

Whitehead Institute researchers identify cellular mechanisms involved in pre-mouth array formation

Whitehead Institute researchers have identified the pre-mouth array--an area of the developing face in embryonic frogs--that "unzips" to surround the mouth opening. Their work highlights the precision necessary to create the mouth and identifies the cellular mechanisms that drive its formation.

9 Aug 2016

Scientist receives $1.7 million grant to study how early life toxic exposures predispose to diabetes

Some studies indicate that early life exposure to pollutants such as PCBs and phthalates can predispose people to disease. Now environmental scientist Alicia Timme-Laragy at the University of Massachusetts Amherst has received a five-year, $1.7 million grant from the National Institute of Environmental Health Sciences for a multi-level study of early life exposure to environmental contaminants and aberrant pancreas development, which may predispose one to diabetes.

9 Aug 2016

New findings on microcephaly may offer clues to explore how Zika virus disrupts brain development

Long before Zika virus made it a household word, the birth defect called microcephaly puzzled scientists and doctors -- even as it changed the lives of the babies born with it during the pre-Zika era.

8 Aug 2016

Scientists test endometrial scratching technique in first-time IVF attempters

A NEW simple procedure which involves gently scratching the lining of the womb in the month before IVF treatment, potentially improving treatment success, is being tested on first-time IVF attempters in a groundbreaking study.

3 Aug 2016

Study finds mutations in three new genes can cause rare syndromic CHD disorders

Researchers at The University of Nottingham have been involved in one of the largest international studies of congenital heart disease, which has discovered gene mutations linked to three new rare congenital heart disorders (CHD).

1 Aug 2016

Male hormones can reverse biological drivers of aging, study shows

Telomerase, an enzyme naturally found in the human organism, is the closest of all known substances to a "cellular elixir of youth." In a recent study, Brazilian and US researchers show that sex hormones can stimulate production of this enzyme.

26 Jul 2016

Key gene controls ability of adult stem cells to regenerate muscle after injury, study finds

A key gene enables the repair of injured muscle throughout life. This is the finding of a study in mice led by researchers at NYU Langone Medical Center and the University of Colorado at Boulder, and published online July 21 in Cell Reports.

21 Jul 2016

Enhancers can boost frequency of transcriptional bursting, study shows

A new study by researchers at Princeton University suggests that sporadic bursts of gene activity may be important features of genetic regulation rather than just occasional mishaps.

20 Jul 2016

Breakthrough research shows cellular stress could be key to variety of birth defects

For the first time, scientists believe they've discovered a cause of multiple types of birth defects triggered by environmental stresses.

20 Jul 2016

Experts propose guidelines to offer clarity for disputes over frozen embryos

In at least 11 cases over the last 24 years, including the appeal of a Missouri case heard in June, U.S. courts have grappled with difficult arguments between men and women who fertilized and froze embryos together, but then disagreed about whether they should be gestated and born.

19 Jul 2016

New TSRI study may bring doctors closer to using gene therapies to grow, repair tendons

With the Rio Olympics just weeks away, many are wondering how Jamaican sprinter Usain Bolt will perform.

19 Jul 2016

Salk scientists propose new molecular criteria for generating naïve stem cells

Salk scientists and colleagues have proposed new molecular criteria for judging just how close any line of laboratory-generated stem cells comes to mimicking embryonic cells seen in the very earliest stages of human development, known as naïve stem cells.

17 Jul 2016

Scientists use machine learning to interpret mosquito genome

Scientists are using machine learning to identify important sequences of DNA within the mosquito genome that regulate how the insect's cells develop and behave.

12 Jul 2016

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year.

6 Jul 2016

Endometrial scratching in women appears to increase chance of clinical pregnancy, live birth

There is a much disputed claim that "injury" to the lining of the uterus - whether inadvertent or deliberate - increases the chance of embryo implantation and thus the chance of pregnancy in certain groups of women having IVF.

4 Jul 2016

Mitochondrial DNA levels may represent accurate, predictive measure of embryo viability in IVF

Despite the claims and counter-claims for new embryo assessment techniques introduced over the past two decades, the search for the holy grail of assisted reproduction - the key to the embryo destined to implant - continues.

4 Jul 2016

Adjunct therapy with human growth hormone in IVF shows no apparent benefit in women

Despite its occasional use as an adjunct in IVF, human growth hormone appears of little benefit to women having difficulty conceiving.

4 Jul 2016

Study could offer new ways to enhance cancer immunotherapy

When an immune T cell divides into two daughter cells, the activity of an enzyme called mTORC1, which controls protein production, splits unevenly between the progeny, producing two cells with different properties.

4 Jul 2016

Biologists elucidate function of Pentagone protein in fruit fly

How do the cells in a human embryo know where they are located in the body and how they should develop? Why do certain cells form a finger while others do not? Freiburg biologists have explained the mechanisms that control these steps by showing why veins form at particular points in the wing of a fruit fly.

29 Jun 2016

Embryo News and Research

UH biologists developing strategies to help regenerate heart muscle cell formation

Whitehead Institute researchers identify cellular mechanisms involved in pre-mouth array formation

Scientist receives $1.7 million grant to study how early life toxic exposures predispose to diabetes

New findings on microcephaly may offer clues to explore how Zika virus disrupts brain development

Scientists test endometrial scratching technique in first-time IVF attempters

Study finds mutations in three new genes can cause rare syndromic CHD disorders

Male hormones can reverse biological drivers of aging, study shows

Key gene controls ability of adult stem cells to regenerate muscle after injury, study finds

Enhancers can boost frequency of transcriptional bursting, study shows

Breakthrough research shows cellular stress could be key to variety of birth defects

Experts propose guidelines to offer clarity for disputes over frozen embryos

New TSRI study may bring doctors closer to using gene therapies to grow, repair tendons

Salk scientists propose new molecular criteria for generating naïve stem cells

Scientists use machine learning to interpret mosquito genome

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Endometrial scratching in women appears to increase chance of clinical pregnancy, live birth

Mitochondrial DNA levels may represent accurate, predictive measure of embryo viability in IVF

Adjunct therapy with human growth hormone in IVF shows no apparent benefit in women

Study could offer new ways to enhance cancer immunotherapy

Biologists elucidate function of Pentagone protein in fruit fly

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