Genes News and Research

RSS

Patterns unique to the striatum observed in people with Huntington's disease

The part of the brain that selectively degenerates in people with Huntington's disease (HD), called the striatum, is almost entirely destroyed in the late stages of the disease. Brain samples from mutant HD gene positive individuals who had not yet developed symptoms by time of death are extremely rare. As a consequence, very little is known about the active disease process that causes the devastating symptoms of HD.

21 Oct 2019

Simple blood test can better identify patients at risk of relapse for B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, a cancer that begins in certain immune system cells and can occur almost anywhere in the body. More than 28,000 people are diagnosed with DLBCL each year.

21 Oct 2019

Timing of food may be nearly as important as how much we eat

Most of what we believe about eating and health stems from decades of research based on a simple premise: The amount of calories consumed affects one's ability to maintain a healthy weight and live longer.

21 Oct 2019

Researchers discover genes linked to sex ratio and male fertility in mice

One of the more recent trends among parents-to-be is the so-called gender reveal, a party complete with pink or blue cake to answer the burning question, "Is it a boy or girl?" After all, it's presumed that there's a 50-50 chance you'd have one or the other.

18 Oct 2019

Blue light and fruit flies: a warning for humans

A new study involving the fruit fly, Drosophila melanogaster, published in the journal npj Aging and Mechanisms of Disease, shows that when flies are kept in darkness, or in white light from which the blue spectrum has been excluded, they live longer, compared to flies kept in alternating 12-hour shifts of blue LED light and darkness. The reason appears to be a speeded-up version of aging; the brain cells, retinal cells and climbing ability, all suffer a breakdown.

18 Oct 2019

Yale scientists build powerful genomic research platform to study cervical cancer

Yale Cancer Center scientists have built a powerful genomic research platform to study cervical cancer, a disease that often is untreatable if it progresses after surgery or primary chemo-radiation treatment.

17 Oct 2019

New research center will encompass a myriad of muscle science and disease investigations

With collaborating labs across the University of Washington campus and at other Seattle-area institutions and beyond, the Center for Translational Muscle Research will encompass a myriad of muscle science and disease investigations.

17 Oct 2019

Building models to reconstruct evolutionary change more accurately than ever before

Remember domain, kingdom, phylum, class, order, family, genus, species and Darwin's tree of life metaphor we learned about in high school biology? That way of describing living-things lineages is just science's best guess about how genes have mutated and split over time to change things into what they are today.

17 Oct 2019

Adding plant-based compound to gene therapy could improve treatment outcomes

Gene therapy has broadened the treatment possibilities for those with immune system deficiencies and blood-based conditions, such as sickle cell anemia and leukemia.

17 Oct 2019

Rare sex-specific brain cells found in male and female mice

Caltech researchers have discovered rare brain cell types that are unique to male mice and other types that are unique to female mice. These sex-specific cells were found in a region of the brain that governs both aggression and mating behaviors.

17 Oct 2019

Researchers identify targeted therapy for adolescent patients with neuroblastoma

Mount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who would otherwise have no treatment options, according to a study published in October in Cancer Cell.

17 Oct 2019

Prolonged exposure to blue light may affect longevity

Prolonged exposure to blue light, such as that which emanates from your phone, computer and household fixtures, could be affecting your longevity, even if it's not shining in your eyes.

17 Oct 2019

Leading children's hospitals to use multi-year federal grant to scale up genomics research collaboration

With a shared vision of accelerating genomic discovery and improving patient outcomes, leaders from Boston Children's Hospital, Children's Hospital of Philadelphia, and Cincinnati Children's Hospital came together in 2015 to form the Genomics Research and Innovation Network.

17 Oct 2019

Signaling defects could cause congenital heart condition

A congenital heart condition known as left ventricular non-compaction (LVNC) - which occurs when muscly projections in the embryonic heart fail to transform into compact heart muscle - could be caused by signaling defects, according to new preclinical research led by Duke-NUS Medical School in Singapore.

17 Oct 2019

Scientists successfully create age-resistant mice with hyper-long telomeres

Researchers have shown that it is possible to extend the life of mice by generating hyper-long telomeres, without using any gene modifying technologies.

17 Oct 2019

New drug treats inflammation related to inherited heart disease in young athletes

When young athletes experiences sudden cardiac death as they run down the playing field, it's usually due to arrhythmogenic cardiomyopathy, an inherited heart disease.

From Johns Hopkins Medicine 17 Oct 2019

Research: Alternative pathway to production of male hormones is present during human fetal development

Research led by the Universities of Birmingham and Manchester has made a connection between the way baby wallabies produce male hormones and how some human girls are born with genitalia that resemble those of a boy.

17 Oct 2019

Genes remember having low social status in the past

A new study in monkeys, published on October 14, 2019, in the Proceedings of the National Academy of Sciences, shows that organisms at the bottom of the social hierarchy live shorter lives. Moreover, they experience more sickness, and may continue to experience health problems despite moving up later. Adverse experiences of social life continue to reflect in their genes much longer than the actual experience, in the form of changes in gene expression via altered gene regulation.

16 Oct 2019

Measuring development in young children: the DNA clock

Scientists have come up with a new discovery that could transform our understanding of how childhood growth and development are measured – the DNA clock. The study, published in the Proceedings of the National Academy of Science, is the first paper to...

16 Oct 2019

Improved antibody validation

Antibodies are used in a variety of clinical and research situations to examine the structure and function, and distribution of proteins. However, many researchers have found a lack of specificity in the functioning of these antibodies. This means that any work conducted using these antibodies will not yield reliable results.

16 Oct 2019

Genes News and Research

Patterns unique to the striatum observed in people with Huntington's disease

Simple blood test can better identify patients at risk of relapse for B-cell lymphoma

Timing of food may be nearly as important as how much we eat

Researchers discover genes linked to sex ratio and male fertility in mice

Blue light and fruit flies: a warning for humans

Yale scientists build powerful genomic research platform to study cervical cancer

New research center will encompass a myriad of muscle science and disease investigations

Building models to reconstruct evolutionary change more accurately than ever before

Adding plant-based compound to gene therapy could improve treatment outcomes

Rare sex-specific brain cells found in male and female mice

Researchers identify targeted therapy for adolescent patients with neuroblastoma

Prolonged exposure to blue light may affect longevity

Leading children's hospitals to use multi-year federal grant to scale up genomics research collaboration

Signaling defects could cause congenital heart condition

Scientists successfully create age-resistant mice with hyper-long telomeres

New drug treats inflammation related to inherited heart disease in young athletes

Research: Alternative pathway to production of male hormones is present during human fetal development

Genes remember having low social status in the past

Measuring development in young children: the DNA clock

Improved antibody validation

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics