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Carnegie Mellon and Yale win NIH grant to advance gene editing technique

A research team from Carnegie Mellon University and Yale University will advance their innovative, synthetic nucleic acid-based gene editing technique under a new grant from the National Institutes of Health's Somatic Cell Genome Editing Program.

7 Oct 2019

New genome-wide association study shines light on genetic risk factors for gout

Researchers, using a method called genome-wide association study, have illuminated the genetic underpinnings of high serum urate, the blood condition that brings on gout.

7 Oct 2019

Spatial Gene Expression Profiling of Neurological Disorders

In this interview, Cedric Uytingco discusses the key benefits of being able to visualize gene expression patterns in neurological samples.

From 10x Genomics, Inc. 7 Oct 2019

Research provides new insights into tumorigenesis of meningioma

The identification of oncogenic mutations has provided further insights into the tumorigenesis of meningioma and the possibility of targeted therapy.

5 Oct 2019

Researchers identify an immune cell that helps keep time in the gut

As people go through their daily and nightly routines, their digestive tracts follow a routine, too: digesting food and absorbing nutrients during waking hours, and replenishing worn-out cells during sleep. Shift work and jet lag can knock sleep schedules and digestive rhythms out of whack.

4 Oct 2019

Stanford study finds genetic similarities among species that use sound waves to navigate

Insect-eating bats navigate effortlessly in the dark and dolphins and killer whales gobble up prey in murky waters thanks in part to specific changes in a set of 18 genes involved in the development of the cochlear ganglion -- a group of nerves that transmit sound from the ear to the brain, according to a study by researchers at Stanford University.

4 Oct 2019

GW researchers show connection between bacteria in the microbiome and colon cancer

A mutant protein found in humans with colon cancer blocks a pathway that regulates proliferation and expansion of cells, increasing amounts of bacterial species associated with the development of colon cancer.

4 Oct 2019

NUS researcher invents novel transfection technique to deliver DNA into immune cells

Immunotherapy is a promising cancer treatment that uses genetically modified immune cells to fight cancer. It can be used as a primary treatment or in combination with other treatments such as radiation and chemotherapy to slow down or stop the growth of cancer cells and prevent them from spreading to other parts of the body.

4 Oct 2019

Study finds prevalence of antibiotic-resistant genes in groundwater

With climate change comes increasing water shortages, and potentially longer periods of drought. As policymakers look urgently to wastewater recycling to stem the gap in water resources, the question is-- how best to reuse water and ensure public safety.

4 Oct 2019

Phage engineering gives antibacterial therapy a new lease of life

Researchers have been identifying and modifying known phages to fight against infectious bacteria.

4 Oct 2019

How mothers transfer the DNA inside their mitochondria to their babies

A recent study has revealed how DNA inside the cell's powerhouse comes from the mother's side.

4 Oct 2019

Men should stay alcohol-free for at least six months before conception

A new study has revealed that men hoping to conceive should stop drinking for at least six months before to prevent congenital heart diseases.

4 Oct 2019

Study sheds new light on transmission dynamics of HIV-1B virus in Indonesia

Research into the molecular phylogeny (evolutionary history) of the HIV-1B virus in Indonesia has succeeded in illuminating the transmission period and routes for three clades (main branches of the virus).

4 Oct 2019

Rare genetic disorder more common than previously thought, report shows

Approximately one in forty-two thousand children are born with a disease called CDKL5 Deficiency Disorder, according to a new medical report recently published in the journal Brain and presented last month at the 13th European Pediatric Neurology Society Congress in Athens, Greece.

4 Oct 2019

Targeting two genetic faults in cancer cells could hold the key to treating leukemia

Faults in two genes directly work together to bring about the deadliest form of blood cancer, scientists have discovered in a study that could pave the way for better treatments.

4 Oct 2019

Study explores how macrophage specialization gets disrupted by liver disease

Every tissue in the human body has an immune cell in it called a macrophage. Macrophages play important roles in the immune system's initial response to bacteria, viruses and wounds.

4 Oct 2019

Penn researchers propose ethical framework that defines brain organoid transplantation

As research involving the transplantation of human "mini-brains"--known as brain organoids--into animals to study disease continues to expand, so do the ethical debates around the practice.

4 Oct 2019

UC Davis researchers awarded $1.5 million NIH grant for CRISPR cancer treatment

What if, instead of killing cancer cells or cells about to become cancerous, you could deliver a repair package and fix them? UC Davis researchers have just been awarded $1.5 million from the National Institutes of Health to start work towards that goal.

3 Oct 2019

Researchers identify gene mutation that causes musculoskeletal problems in children

Researchers have identified a gene mutation that causes developmental delay, intellectual disability, behavioral abnormalities and musculoskeletal problems in children. The newly diagnosed condition, called NKAP-related syndrome, arises from mutations in the NKAP gene, which plays a key role in human development.

3 Oct 2019

Multi-gene testing at point of diagnosis can save all women with breast cancer

A lifetime model evaluating the financial, health and social impact of multi-gene testing (BRCA1/2/PALB2) at diagnosis for all breast cancer patients was found to be extremely cost effective for both UK and US health systems.

3 Oct 2019