pH News and Research

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pH comes from the term “power of Hydrogen”, or the hydrogen ion concentration present in a given solution. It helps to measure the acidity or alkalinity of a substance.

State highlights: New abortion restrictions in Louisiana; aging gracefully in the Gopher State

A bill that could result in the shuttering of up to four of Louisiana's five abortion clinics overwhelmingly received full passage from the Louisiana Legislature Wednesday (May 21), and Gov. Bobby Jindal has indicated he will sign it into law. The legislation is, in part, based on a similar measure passed in Texas last year and led to the closing of several abortion clinics in that state. In its last legislative hurdle, the House concurred an amendment on Wednesday (May 21) that was added to the bill on the Senate side (Lane, 5/22).

23 May 2014

Danish researchers provide valuable insight into basic mechanisms of stem cell differentiation

The world has great expectations that stem cell research one day will revolutionize medicine. But in order to exploit the potential of stem cells, we need to understand how their development is regulated.

23 May 2014

Novel drug for patients with inoperable CTEPH shows improvement in international trial

After a year of being treated with a novel drug, patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH) and those with persistent or recurrent pulmonary hypertension after an operation for the disease showed sustained improvement in a multicenter, international trial presented at the 2014 American Thoracic Society International Conference.

20 May 2014

Study: E-cigarettes appear to increase virulence of drug- resistant and life-threatening bacteria

Despite being touted by their manufacturers as a healthy alternative to cigarettes, e-cigarettes appear in a laboratory study to increase the virulence of drug- resistant and potentially life-threatening bacteria, while decreasing the ability of human cells to kill these bacteria

19 May 2014

PAH risk factors identified for systemic sclerosis patients

Researchers have identified clinical features that could help predict which patients with systemic sclerosis are likely to go on to develop pulmonary arterial hypertension (PAH) and therefore benefit most from early treatment.

13 May 2014

Bioengineers develop tool that reacts to chemical changes caused by cancer cells

Bioengineers at the University of Rome Tor Vergata and the University of Montreal have used DNA to develop a tool that detects and reacts to chemical changes caused by cancer cells and that may one day be used to deliver drugs to tumor cells.

8 May 2014

Ambrisentan cleared for use with phenprocoumon

Starting treatment with ambrisentan does not necessitate adjusting the dose of the oral anticoagulant phenprocoumon in patients with pulmonary hypertension who require both medications, report researchers.

7 May 2014

ARIAD provides update on corporate developments, reports Q1 2014 financial results

ARIAD Pharmaceuticals, Inc. today reported financial results for the first quarter of 2014, including revenue from sales of Iclusig® (ponatinib) and licensing agreements. The Company also provided an update on corporate developments.

7 May 2014

New molecular "clamps" offer powerful new tool for identifying individuals with increased risk of cancer

An international research team has built molecular "clamps" out of DNA that offer a powerful new tool for identifying individuals with an increased risk of cancer.

7 May 2014

Phosphate linked to cause high blood pressure and heart disease

Researchers find link between phosphate rich foods and an enzyme linked to cardiovascular disease. The findings also link phosphates to renal disease.

6 May 2014

Report focuses on behavioral issues linked with patients' self-management of type 2 diabetes

Clinical Therapeutics features a special report in its April issue focusing primarily on the behavioral issues associated with patients' self-management of type 2 diabetes.

29 Apr 2014

Noval neuroimaging technique enables detailed insights into mitochondria

Reactive oxygen species are important intracellular signaling molecules, but their mode of action is complex: In low concentrations they regulate key aspects of cellular function and behavior, while at high concentrations they can cause "oxidative stress", which damages organelles, membranes and DNA.

25 Apr 2014

Measuring tumors' oxygen levels could help doctors make decisions about treatments

Unlike healthy cells, cancer cells thrive when deprived of oxygen. Tumors in low-oxygen environments tend to be more resistant to therapy and spread more aggressively to other parts of the body.

25 Apr 2014

Multifunctional microcapsules can be produced from tannic acid and metals

Microcapsules with a broad spectrum of applications in biomedicine, catalysis, and technology can be produced by using plant-derived, phenolic tannic acid and a variety of metals. The capsules are formed by a simple self-assembly process, and their properties can be controlled through the choice of metal, as demonstrated by a team of Australian and German researchers in the journal Angewandte Chemie.

16 Apr 2014

Akebia completes enrollment in ongoing 200-patient Phase 2b study of AKB-6548

Akebia Therapeutics, Inc., a biopharmaceutical company focused on the development of novel proprietary therapeutics based on hypoxia-inducible factor (HIF) biology and the commercialization of these products for patients with kidney disease, today announced it has completed enrollment in its ongoing 200-patient Phase 2b study of AKB-6548 for the treatment of anemia associated with chronic kidney disease (CKD) in patients who are not dependent on dialysis.

16 Apr 2014

Novel prediction model improves patient outcomes after paracetamol-induced acute liver failure

In the UK paracetamol toxicity is the most common cause of ALF and has a high mortality rate. It is estimated that 150 to 200 deaths and 15 to 20 LTs occur as a result of poisoning each year in England and Wales.

10 Apr 2014

Study finds pharmacist-patient telephone consultations appear to reduce hospitalizations

Having a pharmacist call patients at home to go over their medications can identify many medication-based problems. However, a new study in Health Services Research found that pharmacist-patient telephone consultations only appear to reduce hospitalizations in patients who are least at risk.

10 Apr 2014

Clinical Therapeutics features a special report on trans fat

Clinical Therapeutics features a special report in its March issue focusing on the science and policy leading up to the US Food and Drug Administration's (FDA) preliminary steps toward restricting industrially produced trans fatty acids, or trans fat, at the federal level.

3 Apr 2014

Bayer’s Adempas now available in the UK to treat patients with CTEPH

Adempas (riociguat) is available in the UK today as the first drug treatment for CTEPH, to treat adult patients with WHO Functional Class (FC) II to III with inoperable or persistent disease to improve exercise capacity.

1 Apr 2014

Uppsala researchers develop nano paper filter that can remove virus particles

Nanotechnology and Functional Materials, Uppsala University have developed a paper filter, which can remove virus particles with the efficiency matching that of the best industrial virus filters. The paper filter consists of 100 percent high purity cellulose nanofibers, directly derived from nature.

1 Apr 2014

pH News and Research

Further Reading

State highlights: New abortion restrictions in Louisiana; aging gracefully in the Gopher State

Danish researchers provide valuable insight into basic mechanisms of stem cell differentiation

Novel drug for patients with inoperable CTEPH shows improvement in international trial

Study: E-cigarettes appear to increase virulence of drug- resistant and life-threatening bacteria

PAH risk factors identified for systemic sclerosis patients

Bioengineers develop tool that reacts to chemical changes caused by cancer cells

Ambrisentan cleared for use with phenprocoumon

ARIAD provides update on corporate developments, reports Q1 2014 financial results

New molecular "clamps" offer powerful new tool for identifying individuals with increased risk of cancer

Phosphate linked to cause high blood pressure and heart disease

Report focuses on behavioral issues linked with patients' self-management of type 2 diabetes

Noval neuroimaging technique enables detailed insights into mitochondria

Measuring tumors' oxygen levels could help doctors make decisions about treatments

Multifunctional microcapsules can be produced from tannic acid and metals

Akebia completes enrollment in ongoing 200-patient Phase 2b study of AKB-6548

Novel prediction model improves patient outcomes after paracetamol-induced acute liver failure

Study finds pharmacist-patient telephone consultations appear to reduce hospitalizations

Clinical Therapeutics features a special report on trans fat

Bayer’s Adempas now available in the UK to treat patients with CTEPH

Uppsala researchers develop nano paper filter that can remove virus particles

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