pH News and Research

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pH comes from the term “power of Hydrogen”, or the hydrogen ion concentration present in a given solution. It helps to measure the acidity or alkalinity of a substance.

Researchers identify histone proteins that may be key to generate induced totipotent stem cells

One major challenge in stem cell research has been to reprogram differentiated cells to a totipotent state. Researchers from RIKEN in Japan have identified a duo of histone proteins that dramatically enhance the generation of induced pluripotent stem cells (iPS cells) and may be the key to generating induced totipotent stem cells.

7 Feb 2014

Pre-capillary pulmonary hypertension common in severe heart failure

Pulmonary hypertension is common in patients with heart failure and is likely to include a pre-capillary component, research suggests.

6 Feb 2014

Chest radiography highly predictive of pulmonary hypertension

Chest radiography is very accurate for predicting pulmonary hypertension, report researchers.

3 Feb 2014

Study shows taking vitamin D2 supplements may result in higher muscle damage in athletes

Power athletes and others looking for an edge to improve their performance should avoid taking vitamin D2.

28 Jan 2014

New injectable material delivers drug therapies and sensor technology to targeted areas in human body

A new injectable material designed to deliver drug therapies and sensor technology to targeted areas within the human body is being developed by a Texas A&M University biomedical engineer who says the system can lock its payload in place and control how it is released.

23 Jan 2014

High-protein diet increases chance of developing kidney stones, other renal diseases

High-protein diets, like the popular Dr. Dukan diet, increase the long-term risk of developing kidney disease and have a negative effect on renal urinary and morphological markers. What's more, they may promote serious pathologies like nephrolithiasis (calcium kidney stones) because they drastically reduce urinary citrate (an inhibitor of calcium salt crystallization) and urinary pH, and increase urinary calcium (to compensate for the metabolic acidity caused by excess protein).

22 Jan 2014

Study: High-protein diet increases chance of developing kidney stones and other renal diseases

An experiment by scientists at the University of Granada, Spain, shows a high-protein diet increases the chance of developing kidney stones and other renal diseases.

22 Jan 2014

Clinical rule stratifies CAP patients’ cardiac risk

Researchers have generated and validated a clinical rule that accurately stratifies patients hospitalized for community acquired pneumonia according to their risk for cardiac complications.

20 Jan 2014

Erosive GERD treatments: an interview with Professor Joaquim Moraes-Filho, University of São Paulo Medical School

Gastroesophageal Reflux Disease (GERD) is a condition that develops when the reflux of stomach contents causes troublesome symptoms and/or complications.

20 Jan 2014

ARIAD Pharmaceuticals' Iclusig now commercially available to patients in the U.S.

ARIAD Pharmaceuticals, Inc. today announced the commercial availability of Iclusig (ponatinib) for adult patients with refractory chronic myeloid leukemia and Philadelphia-chromosome positive acute lymphoblastic leukemia in the United States. ARIAD has begun shipping Iclusig to Biologics, Inc., its exclusive specialty pharmacy, which is now filling prescriptions from physicians and distributing the cancer medicine to patients.

18 Jan 2014

Researchers develop "smart" hydrogel that can deliver medicine on demand

Researchers at the University of Delaware have developed a "smart" hydrogel that can deliver medicine on demand, in response to mechanical force.

16 Jan 2014

MRI method to map creatine in heart may help detect disorders earlier than traditional methods

A new MRI method to map creatine at higher resolutions in the heart may help clinicians and scientists find abnormalities and disorders earlier than traditional diagnostic methods, researchers at the Perelman School of Medicine at the University of Pennsylvania suggest in a new study published online today in Nature Medicine.

13 Jan 2014

New study gives hope for novel glioblastoma multiforme treatment

A new study is giving researchers hope that novel targeted therapies can be developed for glioblastoma multiforme, the most common and most aggressive form of brain cancer, after demonstrating for the first time that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) is a driving force behind the disease's aggressive and invasive nature.

9 Jan 2014

OxThera announces initiation of Oxabact clinical study in Primary Hyperoxaluria

OxThera AB, a Stockholm-based privately-held biopharmaceutical company, today announced that it has initiated a clinical study in Primary Hyperoxaluria. This announcement bolsters the Company's position as a leader in developing therapies for hyperoxaluria, a debilitating condition that, if untreated, leads to kidney damage and end-stage renal disease.

8 Jan 2014

Minnesota professor receives Hazelden's Dan Anderson Research Award for hybrid CBT study

Matt G. Kushner, Ph.D., professor of Psychiatry, University of Minnesota (Minneapolis) has earned the latest Dan Anderson Research Award for his study examining the effectiveness of a hybrid cognitive behavioral therapy in the treatment of individuals with co-occurring anxiety disorders and alcohol dependence.

7 Jan 2014

Women In Government announces launch of Pulmonary Hypertension Legislative Toolkit

Women In Government today announced the launch of its Pulmonary Hypertension Legislative Toolkit, designed to provide information and resources regarding Pulmonary Hypertension for women state legislators.

3 Jan 2014

Reflux disease diagnosis: an interview with Professor Peter Dettmar, Managing Director of RD Biomed Limited

Generally speaking, reflux has been a major chronic issue for probably the last 40 or 50 years. When you look at the global population, depending on which country we're talking about, around 20% to 40% of individuals have reflux disease within their populations.

23 Dec 2013

MGC Diagnostics fourth quarter revenue increases 11% to $9.1 million

MGC Diagnostics Corporation, a global medical technology company, today reported financial results for the fourth quarter and year ended October 31, 2013.

19 Dec 2013

FDA accepts Regeneron's EYLEA Injection sBLA for standard review

Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has accepted for standard review the Company's supplemental Biologics License Application for EYLEA (aflibercept) Injection for the treatment of Diabetic Macular Edema.

18 Dec 2013

FDA accepts Shield Therapeutics' IND application to begin ST10 Phase 3 pivotal study for IDA treatment

Shield Therapeutics, an independent specialty pharmaceutical company focused on the development of mineral-derived hospital pharmaceuticals, today announces that the US Food and Drug Administration has accepted its Investigational New Drug application to initiate a Phase 3 pivotal study of ST10, its novel oral iron-replacement therapy, for the treatment of iron deficiency anaemia in pre-dialysis patients with chronic kidney disease. The Company plans to initiate the Phase 3 study in the US in H1 2014 and positive data would be the cornerstone of a subsequent NDA submission.

16 Dec 2013

pH News and Research

Further Reading

Researchers identify histone proteins that may be key to generate induced totipotent stem cells

Pre-capillary pulmonary hypertension common in severe heart failure

Chest radiography highly predictive of pulmonary hypertension

Study shows taking vitamin D2 supplements may result in higher muscle damage in athletes

New injectable material delivers drug therapies and sensor technology to targeted areas in human body

High-protein diet increases chance of developing kidney stones, other renal diseases

Study: High-protein diet increases chance of developing kidney stones and other renal diseases

Clinical rule stratifies CAP patients’ cardiac risk

Erosive GERD treatments: an interview with Professor Joaquim Moraes-Filho, University of São Paulo Medical School

ARIAD Pharmaceuticals' Iclusig now commercially available to patients in the U.S.

Researchers develop "smart" hydrogel that can deliver medicine on demand

MRI method to map creatine in heart may help detect disorders earlier than traditional methods

New study gives hope for novel glioblastoma multiforme treatment

OxThera announces initiation of Oxabact clinical study in Primary Hyperoxaluria

Minnesota professor receives Hazelden's Dan Anderson Research Award for hybrid CBT study

Women In Government announces launch of Pulmonary Hypertension Legislative Toolkit

Reflux disease diagnosis: an interview with Professor Peter Dettmar, Managing Director of RD Biomed Limited

MGC Diagnostics fourth quarter revenue increases 11% to $9.1 million

FDA accepts Regeneron's EYLEA Injection sBLA for standard review

FDA accepts Shield Therapeutics' IND application to begin ST10 Phase 3 pivotal study for IDA treatment

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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