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PID1 gene increases killing effect of chemotherapy drugs on brain tumor cells

Investigators at The Saban Research Institute of Children's Hospital Los Angeles have found that the gene PID1 enhances killing of medulloblastoma and glioblastoma cells.

11 Apr 2017

Researchers use genetic manipulation to regenerate auditory hair cells in adult mice

In an apparent first, St. Jude Children's Research Hospital investigators have used genetic manipulation to regenerate auditory hair cells in adult mice. The research marks a possible advance in treatment of hearing loss in humans. The study appears today in the journal Cell Reports.

11 Apr 2017

Researchers uncover mechanism that leads to disorders in pancreatic development, infant diabetes

Researchers at the University of Helsinki, Finland, have uncovered a mechanism through which a mutation in the STAT3 gene leads to a disorder in the development of the pancreas and to infant diabetes.

11 Apr 2017

Scientists discover promising target to treat highly aggressive brain tumor in infants

Using state-of-the-art gene editing technology, scientists from Ann & Robert H. Lurie Children's Hospital of Chicago have discovered a promising target to treat atypical teratoid/rhabdoid tumor (AT/RT) – a highly aggressive and therapy resistant brain tumor that mostly occurs in infants.

11 Apr 2017

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

An antimicrobial protein caused a dramatic reduction in the creamy white lesions associated with oral thrush in a preclinical study, report microbiologists with McGovern Medical School at The University of Texas Health Science Center at Houston.

11 Apr 2017

Activation of specific protein could lead to acute lymphoblastic leukemia, study reveals

The discovery of a protein signature that is highly predictive of leukemia could lead to novel treatments of the leading childhood cancer, according to new study showing that competition among certain proteins causes an imbalance that leads to leukemia.

11 Apr 2017

Researchers design first light-activated drug for treatment of pain

A team of the Institute of Neurosciences of the University of Barcelona has participated in the design of the first light-activated drug -the JF-NP-26, for the treatment of pain, according to a research with animal models published in the journal eLife.

11 Apr 2017

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

Zika virus is a mosquito-borne infectious disease linked to certain birth defects in infants in South and Central America and the United States.

11 Apr 2017

Innovative collaboration focuses on uncovering role of extracellular matrix in heart health

Shedding light on the unknown role of the extracellular matrix in heart health and disease is the focus of an innovative collaboration between the American Heart Association, the world's leading voluntary health organization devoted to fighting cardiovascular disease, and The Paul G. Allen Frontiers Group.

10 Apr 2017

Salk Institute receives additional $3 million Glenn Foundation gift to continue aging research

The Salk Institute has received a $3 million gift from the Glenn Foundation for Medical Research for the second time in 4 years, enabling the Institute to continue investigating the biology of normal human aging and age-related diseases.

10 Apr 2017

New study finds link between neural tube defects in infants and neurodegenerative diseases

A new study has found a link between neurological birth defects in infants commonly found in pregnant women with diabetes and several neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases.

10 Apr 2017

High level of protein appears to diminish energy burning power of brown fat

Too much of a protein already associated with prostate cancer appears to also diminish the energy burning power of brown fat, scientists report.

10 Apr 2017

Researchers develop blood test to detect intracranial bleeding in infants with abusive head trauma

Researchers at Children's Hospital of Pittsburgh of UPMC and University of Pittsburgh School of Medicine have developed and refined a blood test that could help clinicians identify infants who may have had bleeding of the brain as a result of abusive head trauma, sometimes referred to as shaken baby syndrome.

10 Apr 2017

Study uncovers novel role for cortical interneurons in coding of spatial information

Researchers from King's College London have discovered a specific class of inhibitory neurons in the cerebral cortex which plays a key role in how the brain encodes spatial information. The findings are published in the journal Nature Neuroscience.

10 Apr 2017

MIT engineers develop more sensitive approach to reveal ovarian tumors

Most ovarian cancer is diagnosed at such late stages that patients' survival rates are poor. However, if the cancer is detected earlier, five-year survival rates can be greater than 90 percent.

10 Apr 2017

Study explains how genetic mutations linked to telomere capping complex contribute to cancers

Scientists at The Wistar Institute have unveiled part of the protein complex that protects telomeres - the ends of our chromosomes. The study, published online in Nature Communications, explains how a group of genetic mutations associated with this protein complex contributes to various cancers.

10 Apr 2017

New transgenic mouse could help monitor potential dangers of emerging influenza viruses

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G Protein News and Research

PID1 gene increases killing effect of chemotherapy drugs on brain tumor cells

Researchers use genetic manipulation to regenerate auditory hair cells in adult mice

Researchers uncover mechanism that leads to disorders in pancreatic development, infant diabetes

Scientists discover promising target to treat highly aggressive brain tumor in infants

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

Activation of specific protein could lead to acute lymphoblastic leukemia, study reveals

Researchers design first light-activated drug for treatment of pain

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

Innovative collaboration focuses on uncovering role of extracellular matrix in heart health

Salk Institute receives additional $3 million Glenn Foundation gift to continue aging research

New study finds link between neural tube defects in infants and neurodegenerative diseases

High level of protein appears to diminish energy burning power of brown fat

Researchers develop blood test to detect intracranial bleeding in infants with abusive head trauma

Study uncovers novel role for cortical interneurons in coding of spatial information

MIT engineers develop more sensitive approach to reveal ovarian tumors

Study explains how genetic mutations linked to telomere capping complex contribute to cancers

New transgenic mouse could help monitor potential dangers of emerging influenza viruses

Programmed proteins could lead to inexpensive malaria vaccine

Gene CRY1 variant alters circadian clock contributing to delayed sleep phase disorder, study finds

Viral trigger may underlie development of celiac disease

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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