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pH comes from the term “power of Hydrogen”, or the hydrogen ion concentration present in a given solution. It helps to measure the acidity or alkalinity of a substance.

Novartis receives FDA approval for Ph+ acute lymphoblastic leukemia

The U.S. Food and Drug Administration today approved a new use of Gleevec (imatinib) to treat children newly diagnosed with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL).

27 Jan 2013

Ractopamine can boost pork production, does not affect meat quality or taste

Animal scientists in Brazil have found that a small dose of the feed additive ractopamine can boost pork production without changing how pork looks or tastes.

25 Jan 2013

Bloodstream infections in newborns reduce significantly

Central line associated bloodstream infections (CLABSIs) in newborns were reduced by 58 percent in less than a year in hospital neonatal intensive care units (NICUs) participating in an Agency for Healthcare Research and Quality patient safety program.

25 Jan 2013

EMA adopts positive opinion for Pfizer’s bosutinib conditional approval in the EU

Pfizer Inc. announced today that the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion regarding the conditional marketing authorization of bosutinib in the European Union for the treatment of adult patients with chronic phase (CP), accelerated phase (AP), and blast phase (BP) Philadelphia chromosome positive chronic myelogenous leukemia previously treated with one or more tyrosine kinase inhibitor(s) (TKIs) and for whom imatinib, nilotinib and dasatinib are not considered appropriate treatment options.

19 Jan 2013

Merck’s resubmission of the NDA for suggammadex sodium injection accepted for review by the FDA

Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the resubmission of the New Drug Application (NDA) for sugammadex sodium injection has been accepted for review by the U.S. Food and Drug Administration (FDA). Merck expects the FDA’s review to be completed in the first half of 2013.

7 Jan 2013

Scientists discover process by which mda-9/syntenin contributes to melanoma metastasis

After recently announcing success in eliminating melanoma metastasis in laboratory experiments, scientists at Virginia Commonwealth University Massey Cancer Center have made another important discovery in understanding the process by which the gene mda-9/syntenin contributes to metastasis in melanoma (the spread of skin cancer) and possibly a variety of other cancers.

4 Jan 2013

Philippine President signs family planning bill into law

"The Philippine President has signed into law a family-planning bill that was blocked by the Catholic Church for more than a decade," Al Jazeera reports (12/28). "President Benigno Aquino III signed into a law a bill that promotes contraception and sex education in schools," the Wall Street Journal writes.

3 Jan 2013

Iclusig gets FDA approval for two rare blood and bone marrow diseases

The U.S. Food and Drug Administration today approved Iclusig (ponatinib) to treat adults with chronic myeloid leukemia and Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL), two rare blood and bone marrow diseases.

15 Dec 2012

FDA grants accelerated approval to ARIAD’s Iclusig for treatment of CML, Ph+ ALL

ARIAD Pharmaceuticals, Inc. today announced that following a priority review, the U.S. Food and Drug Administration (FDA) has granted accelerated approval of Iclusig (ponatinib) for the treatment of adult patients with chronic, accelerated or blast phase chronic myeloid leukemia (CML) that is resistant or intolerant to prior tyrosine kinase inhibitor (TKI) therapy or Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) that is resistant or intolerant to prior TKI therapy.

14 Dec 2012

University of Florida initiates enrollment in SPI-1005 Phase II trial for sensorineural hearing loss

The University of Florida (UF) has started enrolling subjects in a new study testing the oral drug developed by Sound Pharmaceuticals, Inc. (SPI-1005) to prevent hearing loss caused by loud music. Loud music or noise can induce temporary and permanent auditory threshold shifts (TTS or PTS).

6 Dec 2012

Ponatinib offers new hope in drug-resistant leukemia

An investigational tyrosine kinase inhibitor, ponatinib, has shown high levels of activity in patients with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.

5 Dec 2012

Clinical trial shows effectiveness of ponatinib in patients with leukemia and lymphoma

Huntsman Cancer Institute researchers Michael Deininger, M.D., Ph.D., and Thomas O'Hare, Ph.D., were part of a team that found a potent oral drug, ponatinib, effective in patients who have developed resistance to standard treatments for chronic myeloid leukemia and Philadelphia chromosome positive acute lymphoblastic lymphoma.

30 Nov 2012

Novartis to highlight key data from extensive oncology portfolio at SABCS and ASH meeting

Novartis will highlight more than 140 presentations on key data from its extensive oncology portfolio at the leading year-end scientific meetings devoted to hematology and breast cancer, demonstrating continued innovation in research and development efforts to advance the care of patients with cancer and rare diseases.

30 Nov 2012

Some nicotine-free snus products can increase risk of caries

It is a myth that snus (Swedish snuff) users today have fewer dental caries. On the contrary, some types of nicotine-free snus contain both carbohydrates and starch that increase the risk of cavities. Those are the findings of a thesis from Sahlgrenska Academy, University of Gothenburg, Sweden.

27 Nov 2012

Electronic device sniffs out sleep apnea syndrome

An electronic nose could be used to diagnose obstructive sleep apnea syndrome, by detecting the presence of volatile organic molecules in the breath of a patient, research suggests.

22 Nov 2012

General guidelines to understand allergic skin conditions

Winter months can bring on the itch as cold weather and indoor heat dry out the skin. It's possible, suggests Chicago allergist, Brian Rotskoff, MD of Clarity Allergy Center, that your winter itch could be caused by more than just the weather. For some people itchy, dry skin is just that, but for others it can be a symptom of atopic dermatitis (eczema), contact dermatitis, or hives (urticaria).

16 Nov 2012

Bono says spending cuts to U.S. development aid would harm global health efforts

Speaking at the World Bank on Wednesday, "Irish rock star and anti-poverty activist Bono said thousands of people could die from AIDS if the United States cuts development assistance to reduce the budget deficit," Reuters reports.

16 Nov 2012

Scientists eliminate metastasis in laboratory experiments

In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin. More than 1 million cases of skin cancer are diagnosed each year in the U.S., and melanoma is the deadliest form.

15 Nov 2012

Atpif1 gene regulates heme synthesis in red blood cell formation

Scientists at the University of Georgia, Harvard Medical School and the University of Utah have discovered a new gene that regulates heme synthesis in red blood cell formation. Heme is the deep-red, iron-containing component of hemoglobin, the protein in red blood cells responsible for transporting oxygen in the blood.

14 Nov 2012

Scientists develop measures to prevent health problems associated with biogenic amines in wine

Biogenic amines may be one of the factors responsible for symptoms such as headaches, gastro-intestinal disorders, shortness of breath, fall in blood pressure, and even unconsciousness and cardiac arrhythmia in severe cases. Histamine, one of the best known members of this group, can cause serious physical problems. Biogenic amines can be produced in the body by natural metabolic activities but are also ingested in larger quantities with food.

8 Nov 2012

pH News and Research

Further Reading

Novartis receives FDA approval for Ph+ acute lymphoblastic leukemia

Ractopamine can boost pork production, does not affect meat quality or taste

Bloodstream infections in newborns reduce significantly

EMA adopts positive opinion for Pfizer’s bosutinib conditional approval in the EU

Merck’s resubmission of the NDA for suggammadex sodium injection accepted for review by the FDA

Scientists discover process by which mda-9/syntenin contributes to melanoma metastasis

Philippine President signs family planning bill into law

Iclusig gets FDA approval for two rare blood and bone marrow diseases

FDA grants accelerated approval to ARIAD’s Iclusig for treatment of CML, Ph+ ALL

University of Florida initiates enrollment in SPI-1005 Phase II trial for sensorineural hearing loss

Ponatinib offers new hope in drug-resistant leukemia

Clinical trial shows effectiveness of ponatinib in patients with leukemia and lymphoma

Novartis to highlight key data from extensive oncology portfolio at SABCS and ASH meeting

Some nicotine-free snus products can increase risk of caries

Electronic device sniffs out sleep apnea syndrome

General guidelines to understand allergic skin conditions

Bono says spending cuts to U.S. development aid would harm global health efforts

Scientists eliminate metastasis in laboratory experiments

Atpif1 gene regulates heme synthesis in red blood cell formation

Scientists develop measures to prevent health problems associated with biogenic amines in wine

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