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Simultaneous mutation of two nonessential genes can cause cancer cell death

A Ludwig Cancer Research study has identified a new instance in which the simultaneous mutation of two nonessential genes - neither of which is on its own vital to cell survival - can cause cancer cell death.

28 Jul 2020

FDA approves first CAR T-cell therapy for patients with mantle cell lymphoma

The U.S. Food and Drug Administration granted accelerated approval for brexucabtagene autoleucel (TECARTUS™, formerly KTE-X19) as the first and only CAR T-cell therapy for patients with mantle cell lymphoma (MCL) relapsed or refractory to prior treatments.

28 Jul 2020

New approach reduces power requirements of neural interfaces while improving accuracy

By tuning into a subset of brain waves, University of Michigan researchers have dramatically reduced the power requirements of neural interfaces while improving their accuracy--a discovery that could lead to long-lasting brain implants that can both treat neurological diseases and enable mind-controlled prosthetics and machines.

27 Jul 2020

Ebola survivors have long-lasting severe immune dysfunction

In the 2013-2016 Ebola outbreak in West Africa, more than 28,000 people were infected, causing over 11,000 deaths.

27 Jul 2020

Low plasma vitamin D level appears to be an independent risk factor for COVID-19 infection

Vitamin D is recognized as an important co-factor in several physiological processes linked with bone and calcium metabolism, and also in diverse non-skeletal outcomes, including autoimmune diseases, cardiovascular diseases, type 2 diabetes, obesity and cognitive decline, and infections.

27 Jul 2020

Brigham to play two key roles in phase 3 trial of COVID-19 vaccine candidate

A vaccine candidate for preventing COVID-19 is advancing to a 30,000-participant phase 3 trial that begins today, and Brigham and Women's Hospital will play two key roles in the trial's next phase.

27 Jul 2020

Overweight, obesity linked with low semen quality parameters

Infertility affects between 10 and 15% of all couples of reproductive ages and can be caused by a wide variety of factors: genetic, physiological, environmental and nutritional.

27 Jul 2020

New review provides an update on management of premenopausal osteoporosis

Osteoporosis, a disease which leads to bone fragility and an increased risk of fractures, is very common among postmenopausal women, affecting around one in three over the age of 50 worldwide.

27 Jul 2020

NAU researcher is studying respiratory mechanics in adult survivors of preterm birth

JJ Duke, an assistant professor in Northern Arizona University's Department of Biological Sciences, is studying respiratory mechanics--the "how" of breathing.

27 Jul 2020

Clinical trials of hydroxychloroquine in COVID-19 outpatients reported as safe

According to new research, the use of hydroxychloroquine among outpatients in clinical trials, without high-risk factors for cardiac arrhythmia, is safe.

27 Jul 2020

Study provides new insights into the host cellular response to SARS-CoV-2 infection

The COVID-19 pandemic caused by the new coronavirus has created an unprecedented public health challenge globally. Little was known about how the infecting cells respond to the virus and how the virus hijacks the host cellular machinery.

27 Jul 2020

New approach could enable wider adoption of COVID-19 testing for diagnosis in research laboratories

Clinician-scientists at Nanyang Technological University, Singapore's (NTU Singapore) Lee Kong Chian School of Medicine (LKCMedicine) have demonstrated a way to improve the speed, handling time and cost of COVID-19 laboratory tests.

27 Jul 2020

Researchers identify anticoagulation agent that suppresses SARS-CoV-2 replication in vitro

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause acute respiratory distress syndrome, hypercoagulability, hypertension, and multiorgan dysfunction.

27 Jul 2020

Continuous survival of neurons is intrinsically programmed during development

When our neurons -- the principle cells of the brain -- die, so do we.Most neurons are created during embryonic development and have no "backup" after birth. Researchers have generally believed that their survival is determined nearly extrinsically, or by outside forces, such as the tissues and cells that neurons supply with nerve cells.

25 Jul 2020

Researcher receives Outstanding Investigator Award for groundbreaking microvascular and circulation research

Sarah Yuan, MD, PhD, professor and chair of the Department of Molecular Pharmacology and Physiology at the USF Health Morsani College of Medicine, has received a highly competitive National Heart, Lung, and Blood Institute (NHLBI) Outstanding Investigator Award to continue breaking new ground in microvascular and circulation research.

25 Jul 2020

MP Biomedicals and A*STAR jointly develop rapid antibody test kit for COVID-19

MP Biomedicals Asia Pacific Pte Ltd, a diagnostic corporation which has been operating for over 30 years focusing on various infectious disease testing development and manufacturing, today announced the successful development of a rapid antibody test kit for COVID-19, in collaboration with the Agency for Science, Technology and Research.

From MP Biomedicals, LLC 25 Jul 2020

Non-invasive urine test being offered free to the NHS to help clear bladder cancer diagnoses backlog

A HIGHLY accurate urine test which can rule out bladder cancer with a negative-predictive value of 99% using a hospital laboratory’s standard ELISA testing equipment is today being offered free to the NHS to help urologists clear the backlog of people waiting for a diagnosis and monitoring as a result of COVID-19 hospital closures.

25 Jul 2020

Laboratory News and Research

Simultaneous mutation of two nonessential genes can cause cancer cell death

FDA approves first CAR T-cell therapy for patients with mantle cell lymphoma

New approach reduces power requirements of neural interfaces while improving accuracy

Ebola survivors have long-lasting severe immune dysfunction

Low plasma vitamin D level appears to be an independent risk factor for COVID-19 infection

Brigham to play two key roles in phase 3 trial of COVID-19 vaccine candidate

Overweight, obesity linked with low semen quality parameters

New review provides an update on management of premenopausal osteoporosis

NAU researcher is studying respiratory mechanics in adult survivors of preterm birth

Clinical trials of hydroxychloroquine in COVID-19 outpatients reported as safe

Study provides new insights into the host cellular response to SARS-CoV-2 infection

New approach could enable wider adoption of COVID-19 testing for diagnosis in research laboratories

Researchers identify anticoagulation agent that suppresses SARS-CoV-2 replication in vitro

Continuous survival of neurons is intrinsically programmed during development

Researcher receives Outstanding Investigator Award for groundbreaking microvascular and circulation research

MP Biomedicals and A*STAR jointly develop rapid antibody test kit for COVID-19

Non-invasive urine test being offered free to the NHS to help clear bladder cancer diagnoses backlog

Elevated leptin levels may explain why COVID-19 is so dangerous for people with obesity

Exercise equipment in communal gyms have high levels of antibiotic-resistant bacteria

Research shows low risk for healthy travelers to acquire Candida auris

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