Immune Response News and Research

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Experimental HIV vaccine progresses in trials

A novel vaccine targeted to multiple HIV subtypes found worldwide has moved into the second phase of clinical testing, the National Institute of Allergy and Infectious Diseases (NIAID) announced today.

11 Oct 2005

New discoveries help explore the function of regulatory T cells in autoimmune disease and in cancer

More than 150 years after the discovery of Hassall's corpuscles in 1849, the function of these round blobs of cells in the human thymus gland has now been explained. The answer, in turn, ends an intense hunt for the origin of regulatory T cells that has been under way for years.

11 Oct 2005

Health campaigns to tackle river blindness

River blindness is a disease transmitted by biting flies, affecting areas such as West Africa, Nigeria, Congo, the Central African Republic and Central and South America, and causing significant health problems for at least 18 million people.

11 Oct 2005

Influenza evolution in action

On the eve of the 2005-06 flu season, scientists at The Institute for Genomic Research (TIGR) have captured influenza evolution in action. In a study published in this week's journal Nature, the researchers report the first large-scale project to sequence the influenza virus.

5 Oct 2005

Researchers "should rethink what they are doing" in creating drugs based on a fruit-fly model

The first close-up look at a pro-inflammatory signaling molecule involved in immune response in mammals suggests that researchers "should rethink what they are doing" in creating drugs based on a fruit-fly model, scientists say.

4 Oct 2005

Discovery of molecular roots of asthma, arthritis, and multiple sclerosis

The molecular roots of inflammatory and autoimmune diseases such as asthma, arthritis, and multiple sclerosis (MS) have been discovered by a team of researchers led by The University of Texas M. D. Anderson Cancer Center. They say their findings may point to ways to effectively treat these diseases - if not stop them before they start.

4 Oct 2005

Protein secreted by the dog hookworm may advance vaccine development in humans

A paper published in this week's PLoS Medicine shows that vaccination against a protein secreted by the dog hookworm can protect against blood loss and anaemia caused by the same hookworm in dogs.

4 Oct 2005

Johns Hopkins awarded $12 million to study how stem cell therapies can be used to treat hearts damaged by heart attack

Heart specialists at Johns Hopkins Heart Institute have been awarded more than $12 million from the National Heart, Lung, and Blood Institute (NHLBI) to study how stem cell therapies can be used to treat hearts damaged by heart attack or heart failure.

4 Oct 2005

Research may help create drugs to target the molecule-binding pathway, beneficial for treating arthritis and reducing inflammation

3 Oct 2005

Discovery may lead to development of more effective antibiotics

Researchers at the Georgia Institute of Technology and the John Innes Centre in the United Kingdom have uncovered a mechanism with which disease-causing bacteria may thwart the body's natural defense responses. The findings, which could ultimately lead to the development of more effective antibiotics, appear in the September 29, 2005 issue of the journal Nature.

28 Sep 2005

Pain-free needles!

Millions of fearful patients could be saved the pain of vaccinations thanks to revolutionary pain-free needles to be revealed today for the first time at the British Pharmaceutical Conference in Manchester.

28 Sep 2005

Discovered of gene mutations associated with hereditary neuralgic amyotrophy

In a significant advance toward understanding a perplexing and painful neurological disorder, an international team of researchers has discovered gene mutations associated with an inherited chronic pain and weakness syndrome known as hereditary neuralgic amyotrophy (also called HNA).

27 Sep 2005

Cancer vaccine based on the bacterium Listeria monocytogenes, can cure mice with breast tumors

A team from the University of Pennsylvania School of Medicine has shown that by using a cancer vaccine based on the bacterium Listeria monocytogenes, they can cure mice with established breast tumors. Cancer vaccines, which are more properly described as immunotherapy, work by boosting an immune response against tumor-associated antigens.

27 Sep 2005

Surprising immune system cells discovery

Immune system cells are connected to each other by an extensive network of tiny tunnels that, like a building's hidden pneumatic tube system, are used to shoot signals to distant cells.

26 Sep 2005

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.

26 Sep 2005

Researchers discover way to dramatically boost the output of immune system cells from the thymus

Mayo Clinic researchers have discovered a way to dramatically boost the output of immune system cells from the thymus, which may lead to improved cancer vaccines, as well as to ways to otherwise strengthen immune responses.

26 Sep 2005

New technique may provide a better way of monitoring response to melanoma treatment

A new study published in PLoS Medicine describes a way to measure the immune response in people treated with an experimental vaccine to melanoma.

26 Sep 2005

Next generation of effective viral-based therapies for cancer

Researchers at Columbia University Medical Center continue to make strides in their work to develop the next generation of effective viral-based therapies for cancer.

21 Sep 2005

Drug that blocks acid buildup inside cells revs up the immune response to vaccines

Reporting in the current issue of The Journal of Experimental Medicine, Vincenzo Barnaba and his team at the University of Rome show that people receiving booster shots against hepatitis B virus developed more robust immune responses if given a widely used anti-malaria drug called chloroquine.

21 Sep 2005

Research could improve clinical care, help educate women on premature birth

A March of Dimes expert panel has recommended a targeted research agenda designed improve the lives of thousands of babies by preventing premature birth. The agenda has been published in the American Journal of Obstetrics and Gynecology.

20 Sep 2005

Immune Response News and Research

Experimental HIV vaccine progresses in trials

New discoveries help explore the function of regulatory T cells in autoimmune disease and in cancer

Health campaigns to tackle river blindness

Influenza evolution in action

Researchers "should rethink what they are doing" in creating drugs based on a fruit-fly model

Discovery of molecular roots of asthma, arthritis, and multiple sclerosis

Protein secreted by the dog hookworm may advance vaccine development in humans

Johns Hopkins awarded $12 million to study how stem cell therapies can be used to treat hearts damaged by heart attack

Research may help create drugs to target the molecule-binding pathway, beneficial for treating arthritis and reducing inflammation

Discovery may lead to development of more effective antibiotics

Pain-free needles!

Discovered of gene mutations associated with hereditary neuralgic amyotrophy

Cancer vaccine based on the bacterium Listeria monocytogenes, can cure mice with breast tumors

Surprising immune system cells discovery

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Researchers discover way to dramatically boost the output of immune system cells from the thymus

New technique may provide a better way of monitoring response to melanoma treatment

Next generation of effective viral-based therapies for cancer

Drug that blocks acid buildup inside cells revs up the immune response to vaccines

Research could improve clinical care, help educate women on premature birth

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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