Electrophysiology News and Research

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Pregnancy complications may predict future heart disease risk

Complications during pregnancy (or adverse pregnancy outcomes), like gestational diabetes and newly developed high blood pressure, act as nature's stress test and may uncover an individual's risk for heart disease later in life, according to new research published in the JACC, the flagship journal of the American College of Cardiology.

14 Apr 2025

Scientists identify critical enzymes for astrocytic GABA production in Alzheimer’s disease

A research team at the Institute for Basic Science (IBS) has identified a previously unknown enzyme, SIRT2, that plays a key role in memory loss associated with Alzheimer's disease (AD).

14 Apr 2025

Epigenetic discovery offers hope for reducing addiction relapse

New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and thereby the formation of strong drug-related memories, which can trigger relapse in individuals with substance use disorders (SUDs).

10 Apr 2025

Handheld electro shockers may disrupt pacemakers and heart devices

Research has found that handheld electro-shockers commonly used for self defense can potentially interact with cardiac implantable electronic devices (CIEDs) such as pacemakers, putting individuals at risk.

9 Apr 2025

New neurons rebuild damaged circuits in Huntington’s disease

New research shows that the adult brain can generate new neurons that integrate into key motor circuits. The findings demonstrate that stimulating natural brain processes may help repair damaged neural networks in Huntington's and other diseases.

7 Apr 2025

Compound heatwaves linked to increased cardiac deaths

Cardiac deaths increase significantly during compound heatwaves-heatwaves where temperatures are elevated both during the day and overnight-according to a new study in JACC, the flagship journal of the American College of Cardiology.

1 Apr 2025

Atrial fibrillation elevates early-onset dementia risk in younger adults

New research presented at the EHRA 2025, a scientific congress of the European Society of Cardiology, shows that the presence of atrial fibrillation (AF) increases the risk of future dementia by 21% in patients diagnosed with AF under 70 and the risk of early-onset dementia (diagnosed before age 65 years) by 36%.

31 Mar 2025

New AI tool detects elevated heart disease risk in women using ECG

A new AI model can flag female patients who are at higher risk of heart disease based on an electrocardiogram (ECG).

25 Feb 2025

Researchers develop safer and faster approach for diagnosing cardiac conditions

Endomyocardial biopsy (EMB) is a valuable method for diagnosing a range of cardiac conditions, but there is a risk of complication due to its invasive nature. Researchers have now found a way to combine right ventricular (RV) septal EMB, exploiting the benefit of 3D curved conduction system pacing (CSP) sheaths, with subsequent cardiac implantable electronic device (CIED, devices like pacemakers or defibrillators to regulate heart rhythm) implantation, using the same sheath.

20 Feb 2025

Study finds global underuse of medications for cardiovascular disease prevention

Secondary prevention medications for cardiovascular diseases (CVD) are underused globally and additional strategies to increase their use are needed to improve CVD management and reduce premature mortality rates, according to study published today in JACC, the flagship journal of the American College of Cardiology.

4 Feb 2025

Researchers construct a detailed structural map of GABAA receptors in the human brain

Certain proteins found in the human brain have long been known to be critical to controlling how brain cells communicate with each other.

22 Jan 2025

Ozone exposure may contribute to reduced oxygen levels and arterial stiffness

Ozone (O3) exposure may reduce the availability of oxygen in the body, resulting in arterial stiffening due to the body's natural response to create more red blood cells and hemoglobin, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

22 Jan 2025

AI deciphers intracellular signals from extracellular recordings in heart cells

A team of researchers led by the University of California San Diego and Stanford University has developed a noninvasive method to monitor the electrical activity inside heart muscle cells from the outside, avoiding the need to physically penetrate the cells.

16 Jan 2025

Research identifies role of PV interneurons in pain processing

A research team led by Prof. HU Li at the Institute of Psychology of the Chinese Academy of Sciences, has revealed that parvalbumin (PV) interneurons in the primary somatosensory cortex (S1) preferentially encode pain intensity and drive nociceptive-evoked gamma oscillations (GBOs).

13 Jan 2025

Trametinib shows promise in treating severe hypertrophic cardiomyopathy in children

Trametinib, a mitogen-activated protein kinase (MEK) inhibitor, reduces mortality and morbidity in children with severe hypertrophic cardiomyopathy (HCM) caused by pathogenic variants in the RAS/MAPK pathway, according to a study published today in JACC: Basic to Translational Science.

8 Jan 2025

UC Davis surgeon pioneers dual chamber leadless pacemaker in 13-year-old patient

UC Davis Director of Pediatric Electrophysiology Dan Cortez has set another world record: He is the first to implant a dual chamber leadless pacemaker in a child.

20 Dec 2024

Early smoking causes structural and functional heart damage

Cigarette smoking from childhood into early adulthood is associated with an increased risk of premature cardiac injury, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

11 Dec 2024

Cryoablation for PFO closure in AF patients undergoing PVI

New research shows that cryoablation is a safe and effective approach to close congenital patent foramen ovale (PFO, a small hole in the heart) in patients with atrial fibrillation (AF) undergoing pulmonary vein isolation (PVI) in a single procedure.

27 Nov 2024

Researchers identify brain circuit behind sexual rejection in females

A team from the Champalimaud Foundation (CF) has pinpointed a critical neural circuit for sexual rejection, identifying a set of brain cells that play a crucial role in determining whether a female accepts or rejects mating attempts based on her reproductive cycle.

25 Nov 2024