Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

New oral drug shows promise for chronic heart failure treatment

An early clinical study shows that a new oral drug is safe and well-tolerated in patients with chronic heart failure.

24 Jun 2026

Study links COVID-19 to higher sleep apnea risk years after infection

Researchers analyzed more than 910,000 adults and found that SARS-CoV-2 infection was associated with a higher adjusted risk of new-onset obstructive sleep apnea up to 4.5 years later. The association appeared in both hospitalized and non-hospitalized COVID-19 patients, supporting targeted screening in higher-risk post-COVID groups while highlighting the need for objective sleep testing.

24 Jun 2026

Heart failure treatments protect heart function during cancer therapy

The cardioprotective effects of heart failure treatments in patients with cancer were demonstrated today in a presentation at ESC Cardio-Oncology 2026, the annual conference of the European Society of Cardiology's Council of Cardio-Oncology.

19 Jun 2026

Novel gene therapy appears to be safe for Friedreich ataxia cardiomyopathy

A new gene therapy appears to be safe in patients diagnosed with Friedreich ataxia cardiomyopathy, a progressive and fatal inherited cardiac disease, according to a phase 1 clinical trial led by Weill Cornell Medicine researchers.

17 Jun 2026

Resistance training reduces major heart disease risk for active women

Women who lift weights may have a lower risk of major heart disease, especially when combined with aerobic exercise, according to a new study published today in JACC, the flagship journal of the American College of Cardiology.

17 Jun 2026

Smartphone apps and wearables help heart disease patients stay active

Smartphone apps, fitness trackers and wearable devices help people with heart disease get more physical activity in their daily lives, according to an analysis of previous research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

17 Jun 2026

Losing smell and taste may profoundly affect wellbeing

University of East Anglia research reveals that smell loss can affect quality of life as severely as conditions including diabetes, stroke, Parkinson's, and kidney failure.

16 Jun 2026

Lysosomal protein stabilizes mitochondria to prevent severe heart failure

A new study published in Engineering has uncovered a regulatory mechanism linking lysosomal function to mitochondrial stability in pathological cardiac hypertrophy, identifying transient receptor potential mucolipin 1 (TRPML1) as a key protective factor against the progression to heart failure.

16 Jun 2026

American Heart Association launches platform for earlier heart failure risk identification

Nearly 7 million people in the United States are living with heart failure, and that number is expected to grow in the years ahead.

15 Jun 2026

Blood-based indicator assesses organ age to predict disease risk

The candles on your birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others.

15 Jun 2026

Physical activity declines after starting GLP-1 obesity treatments

Adults with obesity losing weight with glucagon-like peptide-1 (GLP-1) receptor agonist medications significantly decreased their physical activity, which is essential to protect muscle, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

AI model could improve screening for primary aldosteronism

A study of a new AI model examining 30 years of routine electronic health records (EHR) data could improve screening for primary aldosteronism, a leading cause of high blood pressure that is often unrecognized but increases patients' risk of cardiovascular complications, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

Intravenous statins during heart attack reduce cardiac muscle damage

Reducing the damage sustained by the heart during a myocardial infarction remains one of the major challenges in cardiology, even when the blocked coronary artery is reopened in a timely manner.

11 Jun 2026

Running a marathon triggers measurable heart changes

Acute cardiac responses to marathon running include biomarker spikes and structural changes, though their long-term impact on heart health needs further study.

11 Jun 2026

Novel report uses two-eyed seeing to bridge Indigenous health knowledge

A novel study among Indigenous communities in Canada utilizing sharing circles as the primary method of qualitative data collection shows that heart health is shaped by emotional, spiritual, social, and systemic factors, with trauma strongly influencing how care is accessed and trusted.

11 Jun 2026

Low blood pressure shows strongest link to Alzheimer's disease

Numerous types of cardiovascular disease and CVD risk factors were linked to a higher risk of Alzheimer's disease, with low blood pressure showing the strongest connection, according to a new analysis published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

10 Jun 2026

Review explores impact of extreme endurance running on heart health

Changes to the heart linked to marathon running vary by age, sex, and training level, finds a synthesis of the available data, published in the open access journal BMJ Open Sport & Exercise Medicine.

10 Jun 2026

Excess weight identified as key driver for cardiovascular-kidney-metabolic syndrome

The first-ever clinical guideline for cardiovascular-kidney-metabolic syndrome, or CKM syndrome, identifies excess weight, especially in the abdomen, as a key driver for the syndrome. T

9 Jun 2026

New clinical guidelines target interconnected heart, kidney and metabolic risks

The American Heart Association and the American College of Cardiology, along with two other leading medical organizations have developed the first-ever guideline aimed at preventing and managing cardiovascular-kidney-metabolic (CKM) syndrome, an interconnected set of health conditions that significantly increase the risk of multiorgan complications and negative cardiovascular outcomes.

9 Jun 2026

Moderate air pollution associated with advanced coronary artery disease

In one of the largest studies to date, researchers examined the relationship between long-term air pollution exposure and coronary atherosclerosis and found that even at moderate levels, long-term exposure to air pollution is associated with more advanced coronary artery disease.

9 Jun 2026