Messenger RNA (mRNA) News and Research

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Stem cells used to create organoids that secrete dental enamel proteins

Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay.

14 Aug 2023

Research breaks ground on new ways of treating blood disorders with gene therapy

Research from experts at Michigan Medicine, the Children's Hospital of Philadelphia and Penn Medicine is breaking ground on new ways of treating blood disorders, such as sickle cell anemia, through gene therapy.

9 Aug 2023

Study discloses vital role of LINC00901 and its regulatory network in pancreatic cancer progression

Chemical modifications of RNA molecules, such as m6A, can critically impact gene expression, influencing various aspects of cancer development and progression.

4 Aug 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

Study identifies potential immune biomarker for pulmonary tuberculosis: a step towards early detection

Researchers have identified a potential immune biomarker associated with pulmonary TB in active patients compared to controls.

19 Jul 2023

Moderna provides an update on regulatory submissions for RSV vaccine candidate, mRNA-1345

Moderna, Inc., a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, today provided an update on regulatory submissions for mRNA-1345, a vaccine for the prevention of RSV-associated lower respiratory tract disease (RSV-LRTD) and acute respiratory disease (ARD) in adults aged 60 years or older.

10 Jul 2023

New therapy to mitigate fragile X syndrome may be on the horizon

An antisense therapy developed by Joel D. Richter, PhD, Sneha Shah, PhD, and Jonathan K. Watts, PhD, at UMass Chan Medical School and Elizabeth Berry-Kravis, MD, PhD, at RUSH University Medical Center, restores production of the protein FMRP in cell samples taken from patients with fragile X syndrome.

5 Jul 2023

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Obesity-induced neuroinflammation significantly contributes to the pathophysiology of depression and Alzheimer's disease. Targeting midlife stage for intervention is crucial to potentially prevent Alzheimer's pathology.

13 Jun 2023

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals - from fuels to fabrics and drugs - beyond the normal repertoire of microbes.

13 Jun 2023

Novel 'CLEVER' method accelerates engineering and genetic study of SARS-CoV-2 and its variants

Researchers described rapid mutagenesis and rescue of SARS-CoV-2 variants without cloning.

16 May 2023

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

A clinical trial of an experimental universal influenza vaccine developed by researchers at the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC), part of the National Institutes of Health, has begun enrolling volunteers at Duke University in Durham, North Carolina.

15 May 2023

New technology can deliver gene therapy directly to the lung

Scientists at UMass Chan Medical School have developed a technology to deliver gene therapy directly to lung tissue through intranasal administration, a development that could potentially create a new class of treatments for lung disease.

2 May 2023

Study sheds light on immune factors responsible for contrasting SARS-CoV-2 outcomes in humans and white-tailed deer

Researchers explored the response of respiratory epithelial cells in deers to SARS-CoV-2.

27 Apr 2023

Researchers uncover the molecular basis for making long-term memories

Helping your mother make pancakes when you were three…riding your bike without training wheels…your first romantic kiss: How do we retain vivid memories of long-ago events? As described in a paper published online on April 25 in Neuron, researchers at Albert Einstein College of Medicine have found the explanation.

25 Apr 2023

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

This paper discusses the use of RNA lipid nanoparticles for cancer immunotherapy, which has shown promising results in clinical use. However, only a small percentage of patients respond to existing immunotherapies, and the paper explores opportunities for improvement.

18 Apr 2023

Messenger RNA (mRNA) News and Research

Stem cells used to create organoids that secrete dental enamel proteins

Research breaks ground on new ways of treating blood disorders with gene therapy

Study discloses vital role of LINC00901 and its regulatory network in pancreatic cancer progression

Tumor-derived GDF-15 suppresses immunotherapy response

Study identifies potential immune biomarker for pulmonary tuberculosis: a step towards early detection

Moderna provides an update on regulatory submissions for RSV vaccine candidate, mRNA-1345

New therapy to mitigate fragile X syndrome may be on the horizon

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Novel 'CLEVER' method accelerates engineering and genetic study of SARS-CoV-2 and its variants

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

New technology can deliver gene therapy directly to the lung

Study sheds light on immune factors responsible for contrasting SARS-CoV-2 outcomes in humans and white-tailed deer

Researchers uncover the molecular basis for making long-term memories

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

Study uncovers a novel fold within the SARS-CoV-2 replication co-factor non-structural protein 9

Overcoming challenges in flavivirus vaccine development: Exploring modern vaccine types for Dengue, Zika, and beyond

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

New solutions to boost Africa’s vaccine production

Delayed presentation of MIS-C following COVID-19

Event guide: The 5th mRNA-Based Therapeutics Summit Europe eBook

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Industry Focus eBook - Cell biology (5th edition)

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring