Antibodies News and Research

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Researchers may have solved 100-year-old puzzle to safely open and close the blood-brain barrier

Cornell University researchers may have solved a 100-year puzzle: How to safely open and close the blood-brain barrier so that therapies to treat Alzheimer's disease, multiple sclerosis and cancers of the central nervous system might effectively be delivered.

14 Sep 2011

OBT, Seattle Genetics form strategic collaboration to discover novel ADCs for cancer

Seattle Genetics, Inc. and Oxford BioTherapeutics today announced that they have formed a strategic collaboration to jointly discover novel antibody-drug conjugates (ADCs) for cancer.

14 Sep 2011

Scientists successfully disrupt function of MYC cancer gene

Dana-Farber Cancer Institute scientists have successfully disrupted the function of a cancer gene involved in the formation of most human tumors by tampering with the gene's "on" switch and growth signals, rather than targeting the gene itself.

12 Sep 2011

Black children more at risk for peanut allergy: Study

U.S. researchers examined the genetic profiles of more than 1,100 urban children of different races, averaging around 3 years of age, and found that black children were more likely to have allergic antibodies to food allergens. The study also found that African ancestry was linked with levels of allergic antibodies to peanut typically associated with clinical peanut allergies.

9 Sep 2011

Landmark discovery in rapid spread of PRL-3 oncoprotein associated aggressive cancers

Scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) have made a landmark discovery in the battle against the rapid spread of aggressive cancers associated with PRL-3 oncoprotein.

9 Sep 2011

Novel solution for purifying stem cell mixtures

Stem cells show great potential to enable treatments for conditions such as spinal injuries or Lou Gehrig's disease, and also as research tools. One of the greatest problems slowing such work is that researchers have found major complications in purifying cell mixtures, for instance to remove stem cells that can cause tumors from cells developed for use in medical treatments.

9 Sep 2011

Possible link between mother's diet and risk of allergies in children

A possible link between what a mother eats during pregnancy and the risk of her child developing allergies has been identified in new research published in this month's The Journal of Physiology.

9 Sep 2011

Researchers identify bouncer protein that plays a vital role in RA prevention

Researchers at Northwestern University Feinberg School of Medicine have discovered why the immune cells of people with rheumatoid arthritis become hyperactive and attack the joints and bones. The immune cells have lost their bouncer, the burly protein that keeps them in line the same way a bouncer in a nightclub controls rowdy patrons.

8 Sep 2011

Beta-glucans can help wounds to heal quickly

Can wounds be helped to heal faster? Yes, says a Norwegian company whose product's active ingredient, beta-glucans, comes from common baker's yeast.

8 Sep 2011

IKEPLUS immunization completely eliminates TB bacteria from infected tissues

A potential vaccine against tuberculosis has been found to completely eliminate tuberculosis bacteria from infected tissues in some mice. The vaccine was created with a strain of bacteria that, due to the absence of a few genes, are unable to avoid its host's first-line immune response.

5 Sep 2011

Researchers discover group of mutations involved in T-cell acute lymphoblastic leukemia

An international team of researchers has found a group of mutations involved in T-cell acute lymphoblastic leukemia (T-ALL), and showed that a group of certain drugs, already in clinical use to treat other diseases, can eliminate the cells carrying these mutations.

5 Sep 2011

Researchers discover protein signals responsible for preserving anti-viral antibodies

Our immune system is capable of a remarkable feat: the ability to remember infections for years, even decades, after they have first been encountered and defeated. While the antibodies we make last only about a month, we retain the means of making them for a lifetime.

3 Sep 2011

Plerixafor drug shows promise against WHIM syndrome

A new study reports that a drug already approved by the Food and Drug Administration for use in patients undergoing a bone marrow transplant may also have promise for treating people who have a rare immune deficiency known as WHIM syndrome.

3 Sep 2011

New clinical data on Bristol-Myers Squibb's NULOJIX to be presented at ESOT 2011 congress

Bristol-Myers Squibb Company today announced that new data on NULOJIX (belatacept) will be presented at the European Society for Organ Transplantation (ESOT) Congress on September 4 -7, 2011 in Glasgow, Scotland, United Kingdom.

2 Sep 2011

Low-cost, portable technique can detect specific proteins in human blood

Blood tests are important diagnostic tools. They accurately tease-out vanishingly small concentrations of proteins and other molecules that help give a picture of overall health or signal the presence of specific diseases. Current testing procedures, however, are expensive and time-consuming, while sophisticated test equipment is bulky and difficult to transport.

2 Sep 2011

Symptom-based viral load testing detects HIV in MSM

Testing for HIV when flu-like symptoms develop may offer a cost-effective alternative for early detection of HIV infection in men who have sex with men (MSM), reports a study in the journal AIDS.

31 Aug 2011

ProteinSimple introduces automated Western Blot

ProteinSimple today introduced a revolutionary new system for protein analysis, Simon and the Simple Western. The Simple Western is a complete reinvention of the Western Blot, and is truly a historic breakthrough for protein research.

From ProteinSimple 30 Aug 2011

Adimab initiates independent collaborations with Biogen Idec and Novo Nordisk

Adimab, LLC, a technology leader in the discovery of fully human antibodies, today announced the initiation of two independent collaborations with Biogen Idec and Novo Nordisk. Over the past two years, Adimab has established collaborations with multiple leading pharmaceutical companies, including: Merck, Roche, Novartis, Pfizer, Eli Lilly, Genentech, Human Genome Sciences, and now Biogen Idec and Novo Nordisk.

29 Aug 2011

Zymeworks, Merck collaborate to develop novel bi-specific antibody therapeutic candidates

Zymeworks Inc. today announced a research collaboration with Merck, known as MSD outside the United States and Canada, around Zymeworks' proprietary Azymetric platform for the development of novel bi-specific antibody therapeutic candidates. Bi-specific antibodies are designed to bind to two different drug targets for broad use in clinical applications such as oncology or autoimmune disease.

29 Aug 2011

PREVENT licenses Amorfix's ProMIS to develop vaccines against misfolded prion diseases

The Pan-Provincial Vaccine Enterprise Inc. (PREVENT), a national Centre of Excellence for Commercialization and Research (CECR), has signed an exclusive license with Amorfix Life Sciences Ltd. of Missisauga, Ontario for the use of their proprietary ProMIS technology in developing vaccines (active immunotherapy) for the treatment of diseases caused by the formation of misfolded prion.

29 Aug 2011

Antibodies News and Research

Researchers may have solved 100-year-old puzzle to safely open and close the blood-brain barrier

OBT, Seattle Genetics form strategic collaboration to discover novel ADCs for cancer

Scientists successfully disrupt function of MYC cancer gene

Black children more at risk for peanut allergy: Study

Landmark discovery in rapid spread of PRL-3 oncoprotein associated aggressive cancers

Novel solution for purifying stem cell mixtures

Possible link between mother's diet and risk of allergies in children

Researchers identify bouncer protein that plays a vital role in RA prevention

Beta-glucans can help wounds to heal quickly

IKEPLUS immunization completely eliminates TB bacteria from infected tissues

Researchers discover group of mutations involved in T-cell acute lymphoblastic leukemia

Researchers discover protein signals responsible for preserving anti-viral antibodies

Plerixafor drug shows promise against WHIM syndrome

New clinical data on Bristol-Myers Squibb's NULOJIX to be presented at ESOT 2011 congress

Low-cost, portable technique can detect specific proteins in human blood

Symptom-based viral load testing detects HIV in MSM

ProteinSimple introduces automated Western Blot

Adimab initiates independent collaborations with Biogen Idec and Novo Nordisk

Zymeworks, Merck collaborate to develop novel bi-specific antibody therapeutic candidates

PREVENT licenses Amorfix's ProMIS to develop vaccines against misfolded prion diseases

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