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Broad neutralization of SARS-CoV-2 spike protein by an unconventional antibody fragment

A new preprint research paper posted to the bioRxiv* server examines the nature and effects of the spike mutations and identifies a vulnerable point that could help develop broad-spectrum protection against circulating variants.

21 Dec 2021

Deletion of autism-linked gene diminishes myelin in mice

Myelin, a sheath of insulation around nerves that enables electrical impulses to efficiently travel through the central nervous system, is diminished in mice that have a gene deletion associated with autism spectrum disorder, new research finds.

21 Dec 2021

FDA approval of long-acting injectable drug marks a vital expansion of HIV prevention options

Yesterday the U.S. Food and Drug Administration announced its first approval of a long-acting HIV prevention medication. Developed by ViiV Healthcare, the medicine is long-acting cabotegravir injected once every two months.

21 Dec 2021

Understanding SARS-CoV-2-induced systemic amyloidosis

A new study proposed that inflammation combined with aggregates of amyloidogenic peptides of SARS-CoV-2 S proteins might induce systemic amyloidosis.

21 Dec 2021

Research reveals the structure and function of a bifunctional protein that transports heme

Heme is an essential part of the protein hemoglobin, which colors human blood red. Heme also is crucial for cytochrome proteins, which power the cell. Humans, animals, plants and bacteria all use heme.

21 Dec 2021

Scientists develop first photo-electrochemical aptasensor to detect SARS-CoV-2 virus in saliva

Scientists at the Universidad Carlos III de Madrid (UC3M) have developed the first photo-electrochemical aptasensor that detects the SARS-CoV-2 virus in a saliva sample.

20 Dec 2021

NIH scientists highlight the urgent need for universal coronavirus vaccines

A growing body of scientific evidence, considered together with ecological reality, strongly suggest that novel coronaviruses will continue to infect bats and other animal reservoirs and potentially emerge to pose a pandemic threat to humans.

16 Dec 2021

$1.5 million award helps U-M researchers to gain new window into the inner workings of cells

The precise shapes of proteins at work inside our cells offer essential clues about the processes that drive health and disease. Structural biologists determine the forms of molecular machines, in atomic detail, to better understand how they function or what happens when they malfunction.

15 Dec 2021

First-of-its-kind gene therapy technique reverses severe hearing loss in mice

Hearing loss has been linked to mutations in at least 100 different genes, but up to 16 percent of genetic hearing loss can be traced to just one gene, STRC, the second most common genetic cause.

15 Dec 2021

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.

12 Dec 2021

Screening FDA-approved compounds shown to possess antiviral or antimicrobial activity for SARS-CoV-2 inhibition

Researchers have screened several compounds that could show the ability to inhibit SARS-CoV-2.

10 Dec 2021

Research suggests targeting fusion peptide-calcium interaction may help treat COVID-19

Researchers discovered that the entry of coronaviruses is a Ca2+-dependent process and focused their studies on the SARS-1 FP-Ca2+ interaction and its effect on membranes using electron spin resonance (ESR).

10 Dec 2021

Scientists determine structure of the molecule associated with ALS for the first time

Scientists have determined for the first time the structure of the molecule associated with amyotrophic lateral sclerosis (ALS) and multiple other neurodegenerative diseases.

9 Dec 2021

Glycans strengthen and lengthen SARS-Cov-2 spike binding to ACE2

New study results provide evidence that the binding between SARS-CoV-2 RBD and host ACE2 receptor is aided by the glycosylation on each protein.

9 Dec 2021

Study reveals how a protein in the blood is attracted to key component of Adenovirus-based vaccines

A collaborative team from the School of Medicine at the University of Cardiff, Wales and a range of US institutions used the UK's national synchrotron, Diamond Light Source, to help reveal the details of how a protein in the blood is attracted to a key component of Adenovirus based vaccines.

8 Dec 2021

Electron News and Research

Broad neutralization of SARS-CoV-2 spike protein by an unconventional antibody fragment

Deletion of autism-linked gene diminishes myelin in mice

FDA approval of long-acting injectable drug marks a vital expansion of HIV prevention options

Understanding SARS-CoV-2-induced systemic amyloidosis

Research reveals the structure and function of a bifunctional protein that transports heme

Scientists develop first photo-electrochemical aptasensor to detect SARS-CoV-2 virus in saliva

NIH scientists highlight the urgent need for universal coronavirus vaccines

$1.5 million award helps U-M researchers to gain new window into the inner workings of cells

First-of-its-kind gene therapy technique reverses severe hearing loss in mice

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

Screening FDA-approved compounds shown to possess antiviral or antimicrobial activity for SARS-CoV-2 inhibition

Research suggests targeting fusion peptide-calcium interaction may help treat COVID-19

Scientists determine structure of the molecule associated with ALS for the first time

Glycans strengthen and lengthen SARS-Cov-2 spike binding to ACE2

Study reveals how a protein in the blood is attracted to key component of Adenovirus-based vaccines

SARS-CoV-2 virus-like particles elicit potent neutralizing antibody response in variant challenge

Using soft X-ray tomography for 3D imaging of cell structures in few minutes

X-ray laser offers new insights into how radiation damage occurs in biological tissue

New insights offered into cell-to-cell propagation of SARS-CoV-2

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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